K Onishi

ORCID: 0009-0005-2807-2916
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Function and Risk Factors
  • Parathyroid Disorders and Treatments
  • Magnesium in Health and Disease
  • Mental Health Research Topics
  • Digital Mental Health Interventions
  • Congenital Heart Disease Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac Ischemia and Reperfusion
  • Pulmonary Hypertension Research and Treatments
  • Cardiac pacing and defibrillation studies
  • Blood groups and transfusion
  • Speech Recognition and Synthesis
  • Complement system in diseases
  • Receptor Mechanisms and Signaling
  • Aortic Disease and Treatment Approaches
  • Linguistics, Language Diversity, and Identity
  • Potassium and Related Disorders
  • Family Caregiving in Mental Illness
  • Heart Failure Treatment and Management
  • Cardiovascular Issues in Pregnancy
  • Circadian rhythm and melatonin
  • Heart Rate Variability and Autonomic Control

Kindai University
2024

Nara Institute of Science and Technology
2023-2024

Kindai University Hospital
2023-2024

Mie University
1996-2013

<h3>Objective:</h3> To assess whether circulating levels of intact parathyroid hormone (intact PTH) in outpatients predict hospitalisation for heart failure (HF). <h3>Methods:</h3> Eighty-eight consecutive with HF were enrolled the study. The independent association between PTH and was assessed using Cox regression analysis. <h3>Results:</h3> Mean (SD) serum significantly increased as New York Heart Association classes (I: 40 (21), II: 55 (24), III: 76 (46), IV: 131 (45) pg/ml). receiver...

10.1136/hrt.2008.147652 article EN Heart 2008-07-24

Background. Abnormal myocardial loading can contribute to left ventricular (LV) mechanical dyssynchrony in patients with end-stage renal disease (ESRD). The aims of this study were characterize and quantify LV function ESRD, elucidate the impact haemodialytic (HD) therapy on these parameters by speckle-tracking strain imaging. Methods. Twenty-three ESRD (63 ± 11 years) before (pre-dialysis group) after HD (post-dialysis 28 normal subjects (control group; 60 10 examined echocardiography....

10.1093/ndt/gfq590 article EN Nephrology Dialysis Transplantation 2010-09-23

<h3>Objective</h3> To assess the impact of serum intact parathyroid hormone (PTH) levels on haemodynamic state and their relations by comparing plasma B-type natriuretic peptide (BNP) levels. <h3>Design</h3> Cross-sectional study in molecular epidemiology. <h3>Setting</h3> Mie University Hospital, Tsu, Japan. <h3>Patients</h3> Consecutive 105 patients with chronic heart failure (CHF). <h3>Main outcome measures</h3> Serum PTH BNP were assessed simultaneously right catheterisation....

10.1136/heartjnl-2012-302779 article EN Heart 2012-11-26

We investigated the effects of MCI-154, a positive inotropic agent that increases myofilament response to Ca++, on Ca++ transients, left ventricular (LV) function and phosphodiesterase (PDE) III activity guinea pig heart, compared them with pimobendan milrinone. In Langendorff hearts loaded fluorescent probe indo-1, LV pressure transient were measured simultaneously. MCI-154 (10(-10)-10(-6) M) increased developed pressure, +dP/dt -dP/dt reduction end-diastolic although it did not affect...

10.1016/s0022-3565(25)12292-1 article EN Journal of Pharmacology and Experimental Therapeutics 1996-02-01

Cognitive behavioral therapy (CBT) is a valuable treatment for mood disorders and anxiety. CBT methods, such as cognitive restructuring, are employed to change automatic negative thoughts more realistic ones.

10.2196/55234 article EN cc-by JMIR Formative Research 2024-08-14

Abstract Background East Asians have smaller aortic valve complexes than individuals from Western countries, and few studies reported transcatheter replacement (TAVR) outcomes in Asian patients with a large annulus. Purpose We aimed to compare the acute long-term of TAVR using balloon-expandable valves (BEVs) self-expandable (SEVs) Methods retrospectively analyzed data Optimized transCathEter vAlvular interveNtion Transcatheter Aortic Valve Implantation (OCEAN-TAVI) registry. A annulus was...

10.1093/eurheartj/ehae666.2442 article EN European Heart Journal 2024-10-01

Abstract Background Coronary microvascular dysfunction (CMD) after percutaneous coronary intervention (PCI) has been reported to be associated not only with periprocedural myocardial infarction, but also poor prognosis. While index of microcirculatory resistance using pressure wire (invasive IMR) conventionally used evaluate CMD, angio-derived IMR (angio-IMR) recently emerged as a noninvasive method and shown good correlation invasive IMR. Previous investigations have already that the...

10.1093/eurheartj/ehae666.1378 article EN European Heart Journal 2024-10-01

Predicting the timing of utterances in dyadic conversations is essential for achieving natural interactions between humans and virtual agents. Since former often use non-verbal cues to adjust order their speech, this study proposes a multimodal model incorporating features using Transformer-based voice activity prediction model. First, line with previous research, we reproduced baseline that utilized audio (audio waveform, frame, history) as inputs. To model, added features: gaze direction,...

10.1145/3623809.3623837 article EN 2023-12-03

We investigated the effect of a new Ca++ sensitizer, MCI-154, which is known to increase myofibrillar sensitivity and maximal Ca(++)-activated force, on transients left ventricular (LV) function in indo-1-loaded Langendorff guinea plg hearts subjected reduction coronary perfusion pressure from 80 40 mm Hg. During low-flow ischemia, LV contractility decreased by 50%, whereas systolic diastolic indo-1 fluorescence ratios increased 10%. The treatment with MCI-154 (10(-10) 10(-6) M) 15 min after...

10.1016/s0022-3565(25)20935-1 article EN Journal of Pharmacology and Experimental Therapeutics 1996-10-01

Ca2+ sensitization of contractile machinery could theoretically enhance the mechanoenergetics heart. We studied effects alkalosis with on within framework relationships left ventricular pressure-volume area (PVA; a measure total mechanical energy), myocardial oxygen consumption per beat (VO2), and contractility index [E(max) (slope end-systolic relation)] in 10 excised, cross-circulated canine hearts. Alkalosis was stably maintained without hypoxia (mean pH 7.66). increased E(max) changing...

10.1152/ajpheart.1996.270.6.h1905 article EN AJP Heart and Circulatory Physiology 1996-06-01

We investigated the effects of EMD-53998 and digoxin on Ca2+ transients left ventricular (LV) function in indo 1-loaded Langendorff guinea pig hearts. (10(-9) to 10(-5) M) (10(-10) 10(-6) increased +dP/dt normal The relative increase by was similar digoxin. At M, LV end-diastolic pressure. Low-flow ischemia decreased 50%, while 1 ratio 10-25%. effectively restored depressed with little effect ratio, but at it markedly elevated pressure beneficial contractile dysfunction disappeared. Digoxin...

10.1152/ajpheart.1996.271.1.h311 article EN AJP Heart and Circulatory Physiology 1996-07-01

The following images are from a 62-year-old woman with uncorrected tetralogy of Fallot and pulmonary atresia. Her presenting symptom was ascites. clinical examination remarkable for cachexia, cyanosis clubbing the fingers. resting pulse 71 b.p.m. irregular. baseline blood pressure 112/40 mmHg, her arterial oxygen saturation 81%. On auscultation, …

10.1093/ehjci/jet122 article EN European Heart Journal - Cardiovascular Imaging 2013-07-03

Abstract Background The vulnerable plaque are called high-risk plaques (HRPs), and coronary computed tomography angiography (CCTA) studies have revealed the following characteristics: (1) lesion density on CT≦30HU (2) positive remodeling, (3) presence of spotty calcification, (4) ΔFractional Flow Reserve derived from CCTA (FFRCT) or Δ Quantitative (QFR)≧0.06 has been cited as a feature these lesions. Therefore, identification HRPs in non-culprit is important to reduce future cardiovascular...

10.1093/eurheartj/ehad655.1463 article EN European Heart Journal 2023-11-01

<sec> <title>BACKGROUND</title> Cognitive behavioral therapy (CBT) is a valuable treatment for mood disorders and anxiety. CBT methods, such as cognitive restructuring, are employed to change automatic negative thoughts more realistic ones. </sec> <title>OBJECTIVE</title> This study extends on previous research conducted by the authors, focused process of correcting ones reducing distress anxiety via with virtual agent. It was aimed investigate whether previously applied agent would achieve...

10.2196/preprints.55234 preprint EN 2023-12-06

Objectives: We sought to assess the diagnostic performance of visual and quantitative analysis stress perfusion CT (CTP) imaging with 320-slice CT, when added coronary computed tomographic angiography (CCTA), against invasively determined fractional flow reserve (FFR) in presence a high calcium score. Background: Cardiac examination integrating CCTA CTP allows for comprehensive assessment arterial stenosis myocardial ischemia. However, further clinical validation is required high-risk...

10.1093/eurheartj/eht309.p2924 article EN European Heart Journal 2013-08-02

Purpose: Secondary hyperparathyroidism develops as a compensatory response to both heart and renal failure. We aimed determine the relation between mortality, function, serum intact parathyroid hormone (PTH) levels in acute failure (AHF) patients. Methods: During 4 year period, we enrolled 269 consecutive patients (age 78±12years, male gender 47%,prior episodes of 41%, body mass index 22±4 kg/m2, initial systolic blood pressure 152±35mmHg) admitted for AHF without coronary...

10.1093/eurheartj/eht310.p5075 article EN European Heart Journal 2013-08-02
Coming Soon ...