- Foot and Ankle Surgery
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Orthopedic Surgery and Rehabilitation
- Pressure Ulcer Prevention and Management
- Mesenchymal stem cell research
- Gestational Diabetes Research and Management
- Tendon Structure and Treatment
- COVID-19 Impact on Reproduction
- Multiple Sclerosis Research Studies
- Spinal Cord Injury Research
- Bone fractures and treatments
- Diagnosis and Treatment of Venous Diseases
- Aortic aneurysm repair treatments
- Peripheral Neuropathies and Disorders
- Forensic Entomology and Diptera Studies
- Cardiac Valve Diseases and Treatments
- Sports injuries and prevention
- Systemic Lupus Erythematosus Research
- Botulinum Toxin and Related Neurological Disorders
- Pain Mechanisms and Treatments
- Aortic Disease and Treatment Approaches
American Orthopaedic Foot and Ankle Society
2024
Sovah Health Martinsville
2017-2018
Professional Education and Research Institute
2013-2016
Brigham and Women's Hospital
2016
Salem VA Medical Center
2013
Southern Arizona VA Health Care System
2012
Mayo Clinic
2008
Westmead Hospital
1994
Background: Allogeneic grafts derived from amnion/chorion are known to be efficacious in healing chronic diabetic foot ulcerations (DFUs). The goal of this study was compare aseptically processed dehydrated human amnion and chorion allograft (dHACA) versus standard care (SOC) facilitating wound closure nonhealing DFUs. Methods: Patients with DFUs treated SOC (off-loading, appropriate debridement, moist care) after a 2-week screening period were randomized either or wound-size-specific dHACA...
Amnion and chorion allografts have shown great promise in healing diabetic foot ulcers (DFUs). Results from an interim analysis of 40 patients demonstrated the accelerated ability a novel aseptically processed, dehydrated human amnion allograft (dHACA). The goal this study was to report on full trial results 80 where dHACA compared with standard care (SOC) achieving wound closure non-healing DFUs. After 2-week screening period, during which DFUs were unsuccessfully treated SOC, randomised...
Abstract We report the first clinical evaluation of a new enzymatic wound debridement product containing tarumase in venous leg ulcer patients. As first‐in‐human study, this was prospective, open‐label, multi‐centre, dose escalation study across five cohorts and involving total 43 patients treated three times weekly for up to 4 weeks (12 applications). The primary secondary endpoints were assess systemic safety, local tolerability, early proof concept both healing. Results indicated that...
Acute thoracic aortic dissection has a high mortality if untreated, so the diagnosis must be rapidly made is to lowered significantly. Multiple imaging techniques are often used. This retrospective study from 1988 1993 assesses usefulness in of chest X-rays, computed tomography (CT) scanning, aortography, magnetic resonance (MRI), trans-thoracic (TTE) and trans-oesophageal (TOE) echocardiography. Forty-two patients with final clinical were studied. The was confirmed 16 (13 at surgery three...