A5047216447- GDF15 and Related Biomarkers
- Renal and related cancers
- Immunotherapy and Immune Responses
- Endoplasmic Reticulum Stress and Disease
- Glioma Diagnosis and Treatment
- Extracellular vesicles in disease
- Macrophage Migration Inhibitory Factor
- Immune cells in cancer
- T-cell and B-cell Immunology
- Ferroptosis and cancer prognosis
- CAR-T cell therapy research
- Circular RNAs in diseases
University of Chinese Academy of Sciences
2023
Shanghai Institute of Nutrition and Health
2023
Air Force Medical University
2022
Effective immunotherapies for patients with glioblastoma (GBM) are urgently needed. Chitinase-3 like-protein-1 (CHI3L1) play important roles in the development of gliomas. However, its role glioma-related immune responses remains unclear. We aimed to comprehensively investigate biological features and clinical value glioma, especially GBM. Transcriptome, proteome single-cell RNA-sequencing databases were enrolled study. Immunostaining immunoblotting performed validation. CHI3L1 was highly...
Background: Calcium signaling is implicated in multiple processes including immune response that important tumor progression. Kidney renal clear cell carcinoma (KIRC) the most frequent histological type of with up to a third cases develop metastases. As result lack in-depth understanding mechanisms underlying KIRC, treatment options have been limited. Here, we aim comprehensively investigate landscape Ca 2+ channels, pumps and exchangers KIRC patients. Methods: The mRNA expression profiles...