A5101495027- Aluminum Alloys Composites Properties
- Plant-Microbe Interactions and Immunity
- Plant Disease Resistance and Genetics
- Monoclonal and Polyclonal Antibodies Research
- Plant Pathogenic Bacteria Studies
- Antifungal resistance and susceptibility
- Systemic Lupus Erythematosus Research
- Magnesium Alloys: Properties and Applications
- Fungal Infections and Studies
- Renal Diseases and Glomerulopathies
- Aquaculture disease management and microbiota
- interferon and immune responses
- Inflammasome and immune disorders
- Color perception and design
- Inflammatory Myopathies and Dermatomyositis
- Skin and Cellular Biology Research
- Autoimmune and Inflammatory Disorders Research
- Syphilis Diagnosis and Treatment
- Aluminum Alloy Microstructure Properties
- Graphene research and applications
- Cytomegalovirus and herpesvirus research
- T-cell and B-cell Immunology
- Ocular Infections and Treatments
- vaccines and immunoinformatics approaches
- Face and Expression Recognition
Central South University
2021-2025
Xiangya Hospital Central South University
2021-2025
Harbin Institute of Technology
2024-2025
Zhejiang Hospital
2024
Shandong First Medical University
2024
First Affiliated Hospital of Xinjiang Medical University
2023
Xinjiang Medical University
2023
Southwest University
2020-2023
Education Department of Hunan Province
2023
Peking Union Medical College Hospital
2016
Dominant-negative somatic mutations of p53 has been identified in the synovium patients with rheumatoid arthritis (RA), which interleukin (IL)-6 established as a pivotal inflammatory cytokine. The aim this study was to clarify significance longstanding inflammation RA by modulating IL-6.We adjuvant-induced (AIA) Lewis rats and treated them activator, then analyzed histopathology IL-6 expression. Human fibroblast-like synoviocytes (FLS) were cultured transfected p53-siRNA or transduced...
Grain refinement is of very important significance for improving the microstructure and mechanical properties Mg alloys. This work investigated how addition various amounts Y element affected Mg-9Al-1Zn alloy. It was found that grain size alloy decreases as content increases. When 1.2 wt.% added, could be reduced from 334.2 μm to 134.6 μm, efficiency 60% achieved. HRTEM analysis demonstrated a good orientation relationship between Al2Y phase interface, therefore, it determined can used...
Aim This study was carried out to investigate the effects of dietary sodium butyrate supplementation on growth performance, carcass traits and intestinal growing-finishing pigs. Methods Results Thirty pigs (27·4 ± 0·4 kg) were randomly assigned receive one three diets: basal diet (negative control group), + 40 ppm zinc bacitracin (positive group) 0·2% (sodium respectively. The experiment lasted for 69 days, including 3 days housing condition adaptation. On day 70, five piglets from each...
Bacterial keratitis is a serious ocular infection that can impair vision or even cause blindness. The clinical use of antibiotics limited due to their low bioavailability and drug resistance. Hence, there need develop novel delivery system for this infectious disease. In study, erythromycin (EM) was encapsulated into bifunctional polyhedral oligomeric silsesquioxane (BPOSS) with the backbone poly-PEG/PPG urethane (BPEP) hydrogel aim improving efficiency in treating bacterial keratitis. A...
Traditional human shape classification usually adopted some key measurements, leading several problems to product ergonomic design. Multivariate analysis is able supplement the disadvantages of traditional method. Among methods multivariate analysis, Principal component (PCA) and Factor (FA) have enjoyed widespread popularity. Though both them are reduce dimensions variances in sample, there differences between PCA FA worth further investigation. The purpose paper demonstrate by analyzing...
Abstract Defects causing concomitant loss of CD25 expression in regulatory T cells (Tregs) have been identified systemic lupus erythematosus (SLE). However, the cause this deficiency is not fully understood. Carcinoembryonic antigen related cell adhesion molecule 1 (CEACAM1), an immune co‐receptor, contributes to general T‐cell function and activation. Our previous study revealed that CEACAM1 was upregulated peripheral blood mononuclear (PBMCs) from patients with SLE. its role remains...
Brucellosis has become a global zoonotic disease, seriously endangering the health of people all over world. Vaccination is an effective strategy for protection against Brucella infection in livestock developed countries. However, current vaccines are pathogenic to humans and pregnant animals, which limits their use. Therefore, it very important improve safety immune vaccine. In this study, different bioinformatics approaches were carried out predict physicochemical properties, T/B epitope,...
Although previous studies on the genotypic diversity and antifungal susceptibility of Cryptococcus neoformans species complex (CNSC) isolates from China revealed ST5 genotype being dominant, information about CNSC Chinese HIV-infected patients is limited. In this study, 171 in Chongqing region Southwest were genotyped using International Society for Human Animal Mycology-multilocus sequence typing consensus scheme, their drug susceptibilities determined following CLSI M27-A3 guidelines....
Abstract The fungus Cryptococcus neoformans is considered the leading cause of death in immunocompromised patients. Despite numerous investigations concerning its molecular epidemiology, there are only a few studies addressing impacts varying factors on genotype-phenotype correlations. It remains largely unknown whether genetic and environmental variabilities among isolates from different sources may have dramatic consequences virulence. In this study, we analyzed 105 Chinese C. isolates,...