- Leptospirosis research and findings
- Veterinary medicine and infectious diseases
- Viral Infections and Vectors
- Humic Substances and Bio-Organic Studies
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Dermatological diseases and infestations
- Neutropenia and Cancer Infections
- Yersinia bacterium, plague, ectoparasites research
- Carcinogens and Genotoxicity Assessment
- Mycobacterium research and diagnosis
- Systemic Sclerosis and Related Diseases
- Rabies epidemiology and control
- Diagnosis and Treatment of Venous Diseases
Agri Food and Biosciences Institute
2012-2023
Government of Northern Ireland
2004
Emory University
1997
The University of Texas System
1982
Anderson Hospital
1982
Infections with fluconazole-resistant Candida albicans isolate have rarely been described in clinical settings other than oropharyngeal candidiasis patients late-stage AIDS. We report on two leukemia who developed fungemia caused by C. after receiving fluconazole prophylaxis (400 mg/day) and empiric amphotericin B therapy (0.5 mg/kg of body weight per day). The MICs for the isolates were > or = 64 micrograms/ml, resistant to azoles had membrane sterol changes consistent a mutation delta...
In disseminated candidiasis, various organs frequently become involved, usually as a consequence of hematogenous spread the organism. However, involvement joints is rare even with dissemination. Nineteen cases joint have previously been reported in adults and 21 children. The most commonly involved has knee; such cases, amphotericin B effective controlling infection. Five patients cancer developed septic arthritis due to Candida species at M. C. Anderson Hospital Tumor Institute past five...
A total of 855 sera from dogs in Greece were tested for antibodies to strains belonging the Pomona, Grippotyphosa and Australis serogroups Leptospira assess exposure levels these serogroups, possible associations with clinical disease evaluate whether findings support inclusion additional serovars dog vaccines. Antibodies detected 110 (12·9%) dogs. The highest seroprevalence (4·9%) was proposed novel serovar Altodouro Pomona serogroup. This also showed a statistically significant association...
The greater white-toothed shrew (Crocidura russula) is an invasive mammalian species that was first recorded in Ireland 2007. It currently occupies area of approximately 7,600 km2 on the island. C. russula normally distributed Northern Africa and Western Europe, previously absent from British Isles. Whilst can have dramatic rapid impacts faunal floral communities, they may also be carriers pathogens facilitating disease transmission potentially naive populations. Pathogenic leptospires are...
A total of 474 serum samples from client owned Irish dogs were tested for the presence antibodies to serovars Canicola, Icterohaemorrhagiae, Bratislava, Autumnalis, Pomona, Altodouro, Grippotyphosa, Mozdok, Hardjobovis and Ballum. Six per cent presented veterinary practitioners problems unrelated leptospirosis showed evidence prior exposure leptospiral belonging serogropus Ballum, Australis, Pomona Sejroe. One unvaccinated dog suspected have seroconversion serogroup Icterohaemorrhagiae....
Current typing of Leptospira strains requires a combination both serological and molecular methods. Study the epidemiology within Pomona serogroup has proved problematic due to limitations This is particularly true two main complexes this group, namely Pomona, Monjakov, Kennewicki cluster in interrogans species Mozdok, Tsaratsovo, Kunming, Altodouro kirschneri Strains from south England have been shown previously belong L serovar which are maintained by small rodents western Europe. While...
Strains of Leptospira interrogans belonging to two very closely related serovars, Icterohaemorrhagiae and Copenhageni, have been associated with disease in mammalian species are the most frequently reported agents human leptospirosis. They considered pathogenic serovars represent more than half leptospires encountered severe infections.Nineteen such isolates from United Kingdom - human, domestic wildlife were typed using three monoclonal antibodies (F12 C3, F70 C14 C24) an attempt elucidate...