A5093098092- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Cancer Genomics and Diagnostics
- Cancer Treatment and Pharmacology
- Cancer Cells and Metastasis
- Tumors and Oncological Cases
- Ovarian cancer diagnosis and treatment
- Cancer Immunotherapy and Biomarkers
- Colorectal and Anal Carcinomas
- Breast Cancer Treatment Studies
- Lymphoma Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Genetic factors in colorectal cancer
- Lung Cancer Treatments and Mutations
- Cytomegalovirus and herpesvirus research
- Immune Cell Function and Interaction
- Head and Neck Cancer Studies
Institut Claudius Regaud
2023-2025
Institut universitaire du cancer de Toulouse Oncopole
2024
Abstract Salivary carcinomas of minor salivary glands are very infrequent tumors. When located in the tongue, therapeutic strategy may comprise upfront surgery, which be debilitating, and/or (chemo‐)radiotherapy. The aim this study was to identify prognostic factors tongue a population‐based cohort. This retrospective multicentric study, based on “Réseau d'Expertise Français sur les Cancers ORL Rares” (REFCOR), included all patients with carcinoma diagnosed between January 2009 and December...
Salivary carcinomas of the tongue represent a therapeutic challenge as their radical excision is particularly mutilating. We aimed to study oncologic and functional outcomes advanced stages salivary tongue. This retrospective multicentric study, based on French national network rare head neck cancers (REFCOR), included all patients with T3-T4 carcinoma tongue, diagnosed between January 2009 December 2018. In total, 47 were included, which 44.7 % underwent surgery. Histologies mostly adenoid...
<h3>Introduction/Background</h3> Homologous recombination deficiency (HRD) exhibit distinct immune characteristics compared to HR Proficient (HRP) ovarian cancers. Tumor infiltrating lymphocytes (TILs) are enriched in HRD tumors, both through innate and adaptive mechanisms. However, there mechanisms for evading recognition the group, is a subset of HRP tumors with enhanced CD8 T cell response better survival. It likely that infiltration alone may not be sufficient characterize tumor...
Abstract Objective To elucidate the prognostic implications of mucosal and deep margin distances in oral tongue squamous cell carcinoma (OTSCC), to assess a different cut‐off value T1‐T2 versus T3‐T4 tumors. Methods This single‐center retrospective study included 223 patients who received surgery for primary OTSCC between January 2017 December 2021. Results Multivariable analysis showed that distance ≥3 mm tumors ≥5 was significantly associated with better RFS OS. Mucosal were globally...