A5103960085- Ion channel regulation and function
- Venomous Animal Envenomation and Studies
- Plant-Microbe Interactions and Immunity
- Systemic Lupus Erythematosus Research
- Plant Molecular Biology Research
- Osteoarthritis Treatment and Mechanisms
- Geochemistry and Elemental Analysis
- Plant Pathogenic Bacteria Studies
- interferon and immune responses
- Immune cells in cancer
- RNA regulation and disease
- Cytomegalovirus and herpesvirus research
- Chronic Lymphocytic Leukemia Research
- Gut microbiota and health
- Plant Gene Expression Analysis
- Biochemical and Structural Characterization
- Inflammasome and immune disorders
- Lipid Membrane Structure and Behavior
- Light effects on plants
- Nematode management and characterization studies
- Bacillus and Francisella bacterial research
- Rheumatoid Arthritis Research and Therapies
- Spectroscopy and Quantum Chemical Studies
- Research on Leishmaniasis Studies
- Cancer, Hypoxia, and Metabolism
Nanjing Agricultural University
2023-2024
China Geological Survey
2024
Chinese Academy of Sciences
2016-2024
Southwest Medical University
2023-2024
Hefei Institutes of Physical Science
2024
Beijing Jishuitan Hospital
2021-2023
Peking University
2021-2023
Anhui University
2020
Institute of Biophysics
1997-2016
Thomas Jefferson University
1993
For a long time Asian scorpion Buthus martensi Karsch (BmK) has been used in Chinese traditional medicine to cure many diseases of nervous system. Here we report the purification and characterization pharmacologically active neurotoxin from BmK. This toxin had little toxicity mice insects but was found have an anti‐epilepsy effect rats, is thus named as BmK peptide (BmK AEP). Its amino‐acid sequence determined by lysylendopeptidase digestion, Edman degradation mass spectrographic analysis....
Remote assessment and diagnosis of functional impairment caused by osteoarthritis (OA) the knee can achieve early intervention patients' impairment, prevent deterioration OA knee, provide remote screening for patients with OA. This study introduced an inertial measurement unit (IMU) sensor-based system to assess lower extremity function perform gait analysis. Then, we compared its accuracy gold-standard motion capture systems.Nine adults were selected participate in a comparative outcomes...
Activation of immune responses leads to an enrichment beneficial microbes in rice panicle. We therefore selected the enriched operational taxonomy units (OTUs) exhibiting direct suppression effects on fungal pathogens, and established a simplified synthetic community (SynCom) which consists three microbes. Application this SynCom exhibits protective effect against pathogen infection rice. Beneficial exhibit positive health not only plants but also animals humans [1-3], give possibility their...
Abstract Objectives To investigate whether machine learning, which is widely used in disease prediction and diagnosis based on demographic data serological markers, can predict herpes occurrence patients with systemic lupus erythematosus (SLE). Methods A total of 286 SLE were included this study, including 200 without 86 herpes. randomly divided into a training group test group, 18 characteristics indicators compared between the two groups. Results We selected basophil, monocyte, white blood...
Summary Rice false smut disease, caused by the fungal pathogen Ustilaginoidea virens , significantly restricts both production and quality of rice grains. However, molecular mechanism underlying resistance against U. remain largely elusive. Transcriptome analysis panicles infected with revealing crucial role genes involved in sakuranetin biosynthesis conferring to pathogen. In vitro assays demonstrated that was most effective at inhibiting mycelial growth, spore germination, host infection ....
Abstract Objectives: Osteoarthritis (OA) is a chronic joint degenerative disease and has become an important health problem for the elderly. However, there still lack of effective drugs treatment OA. Our research combines bioinformatics experimental strategies to determine target resveratrol OA treatment. Methods: First, differentially expressed genes (DEGs) tissues were obtained from related microarray gene expression data. Second, resveratrol, natural polyphenol compound, was used screen...
This study advances our understanding of the Jiangnan Orogenic Belt by integrating high-precision geochronological data with interpretations sedimentary and tectonic environments. Specifically, it addresses controversy over geological significance, origins, significance Shengong Unconfomity: at base Luojiamen Formation. paper shows that formation developed four stages primary source detritus lying in a volcanic arc to south. The also reassesses “unconformity” between Formation Heshangzhen...