A5103042773- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- HER2/EGFR in Cancer Research
- Neurological disorders and treatments
- Child Nutrition and Feeding Issues
- Cancer-related Molecular Pathways
- Cytokine Signaling Pathways and Interactions
- Pluripotent Stem Cells Research
- Dysphagia Assessment and Management
- Neurological diseases and metabolism
Ajou University
2024
Kyung Hee University
2020
CHA University
2012-2019
This study aims to identify distinct microbial and functional biomarkers characteristic of body-first or brain-first subtypes Parkinson's disease (PD). could illuminate the unique pathogenic mechanisms within these subtypes.
Aberrant activation of signal transducer and activator transcription 3 (STAT3) has been documented in various malignancies including triple-negative breast cancers (TNBCs). The STAT3 factor can regulate the different important hallmarks tumor cells, thus, targeting it be a potential strategy for treating TNBC, which only limited therapeutic options are available. In this study, we analyzed possible effect (-)-galiellalactone its novel analogues, SG-1709 SG-1721, determined whether these...
Abstract Parkinson's disease, a complex neurodegenerative disorder characterized by the degeneration of dopamine-producing neurons and presence alpha-synuclein aggregates in Lewy bodies, exhibits clinical diversity prompting proposed classification into two subtypes: body-first, originating peripheral nervous system, brain-first, initiating central system. Recent evidence links gut microbiome dysbiosis to aggregation gut, comprehensive study utilizing shotgun metagenomics explore roles these...