- Genomics and Phylogenetic Studies
- Aquaculture disease management and microbiota
- Cephalopods and Marine Biology
- Gut microbiota and health
- Molecular Biology Techniques and Applications
- Marine Bivalve and Aquaculture Studies
- Identification and Quantification in Food
- Parkinson's Disease Mechanisms and Treatments
- Probiotics and Fermented Foods
- Microbial Community Ecology and Physiology
- Microbial Metabolism and Applications
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Bacteriophages and microbial interactions
- Dysphagia Assessment and Management
- Immune Cell Function and Interaction
- Diet and metabolism studies
- Bacterial Identification and Susceptibility Testing
- Neuroendocrine regulation and behavior
- Mosquito-borne diseases and control
- Myxozoan Parasites in Aquatic Species
- Malaria Research and Control
- Microscopic Colitis
- Viral Infections and Vectors
- Environmental DNA in Biodiversity Studies
Bioscience (China)
2024
Gyeongsang National University
2024
Kyung Hee University
2015-2023
Jiangsu Institute of Parasitic Diseases
1995
Although several studies have identified a distinct gut microbial composition in Parkinson's disease (PD), few investigated the oral microbiome or functional alteration of PD. We aimed to investigate connection between and changes PD-specific using shotgun metagenomic sequencing. The taxonomic was significantly different PD patients healthy controls (P = 0.003 0.001, respectively). Oral Lactobacillus more abundant associated with opportunistic pathogens (FDR-adjusted P < 0.038). Functional...
Invertebrates are a very attractive subject for studying host-microbe interactions because of their simple gut microbial community and host diversity. Studying the composition invertebrate microbiota determining factors is essential understanding symbiotic mechanism. Cephalopods invertebrates that have similar biological properties to vertebrates such as closed circulation system, an advanced nervous well-differentiated digestive system. However, it not currently known whether microbiomes...
This study aims to identify distinct microbial and functional biomarkers characteristic of body-first or brain-first subtypes Parkinson's disease (PD). could illuminate the unique pathogenic mechanisms within these subtypes.
ABSTRACT Abnormalities in the human microbiota are associated with etiology of allergic diseases. Although disease site-specific may be pathophysiology, role nasal is unclear. We sought to characterize site rhinitis, inferior turbinate, subjects rhinitis ( n = 20) and healthy controls 12) examine relationship mucosal occurrence, sensitized allergen number, allergen-specific total IgE levels. Microbial dysbiosis correlated significantly levels representing combined responses but not number...
Two strains, VM2412T and VR2415T, were isolated from the feces of an Andean condor (Vultur gryphus) living in Seoul Grand Park, Gyeonggi-do, South Korea. Cells both strains observed to be Gram-stain positive, non-motile, aerobic, catalase positive oxidase negative. Growth was found occur at 10-30°C, showing optimum growth 30°C. The could tolerate up 15% (w/v) NaCl concentration grow pH 6-9. shared 99.3% 16S rRNA gene sequence similarity each other but identified as two distinct species based...
A novel coccus-shaped, Gram-stain-positive, non-motile and facultative aerobic bacterium, designated strain D7T301T, was isolated from the small intestine of a marten, Martes flavigula, which killed on road in Pocheon-si, Gyeonggi-do, Republic Korea. Grown tryptic soy yeast agar plate, colonies had creamy colour irregular form. The new isolate formed monophyletic clade with Vagococcus penaei CD276T phylogenetic consensus tree based 16S rRNA gene sequence. grew optimally at 37 °C pH 7...
Neonatal calf diarrhea is a common disease leading to major economic loss for cattle producers worldwide. Several infectious and noninfectious factors are implicated in diarrhea, but control remains problematic because of the multifactorial etiology disease. Here, we conducted diagnostic multiplex PCR assay meta-omics analysis (16S rRNA gene-based metataxonomics untargeted transcriptional profiling) rectal content normal diarrheic beef calves (
The SoUth Korean study to PrEvent cognitive impaiRment and protect BRAIN health through lifestyle intervention in at-risk elderly people (SUPERBRAIN) is a part of the World-Wide Finnish Geriatric Intervention Study Prevent Cognitive Impairment Disability (WW-FINGERS) network. This aimed demonstrate effects SUPERBRAIN-based multidomain with nutritional supplements amyloid positive emission tomography (PET) proven early symptomatic Alzheimer's disease patients.Forty-six participants who were...
A strictly anaerobic, Gram-stain-positive, non-motile and coccoid- or oval-shaped bacterium, designated strain KB1T, was isolated from a faecal sample of patient with diverticulitis in South Korea. Degeneracies the 16S rRNA gene sequence KB1T were resolved by cloning, which yielded five different sequences heterogeneity. Phylogenetic analysis based on showed that formed monophyletic branch species genus Blautia, highest similarity to type Blautia producta (97.7-98.9 %), followed coccoides...
Cultivation and isolation of gut bacteria are necessary for understanding their role in the intestinal ecosystem. We isolated a novel bacterium, designated strain BG01T, from faeces patient with Crohn's disease. Strain BG01T was strictly anaerobic, rod-shaped, Gram-variable endospore-forming bacterium. possessed C12 : 0, C18 0 dimethyl aldehyde (DMA) 1 ω9c DMA as predominant cellular fatty acids meso-diaminopimelic acid diagnostic diamino acid. grew at 15-45 °C (optimum, 37 °C), 0-4 % (w/v)...
A novel Gram-stain-negative, non-spore-forming, obligate aerobic, motile, rod-shaped, and flagellated bacterium, designated S11R28T, was isolated from the intestinal tract of a Korean shiner, Coreoleuciscus splendidus. Based on 16S rRNA gene sequences, strain S11R28T identified as member genus Undibacterium in class Betaproteobacteria, closely related to parvum DSM 23061T (98.49 %). The isolate grew at 4-25 °C, pH 6-9, with 0 % (w/v) NaCl, optimally 20 8, absence NaCl. main cellular fatty...
A novel Gram-stain-negative, aerobic, motile and rod-shaped bacterium, designated strain RSG39T, was isolated from the gut of a Korean rockfish, Sebastes schlegelii. The 16S rRNA gene sequence analysis revealed that RSG39T belonged to genus Simplicispira in class Betaproteobacteria its highest similarity shared with S. psychrophila (98.4 %). isolate grew optimally at 20 °C, pH 7 0 % (w/v) NaCl. main respiratory quinone ubiquinone Q-8. major cellular fatty acids were C16 : 0, summed feature 3...
A novel Gram-negative, obligately aerobic, rod-shaped and non-motile bacterium, designated strain K13M18T, was isolated from the intestinal tract of a Korean indigenous fish, oily bitterling (Acheilognathus koreensis). Strain K13M18T formed creamy-pink colonies on marine agar plate. Results phylogenetic analysis based 16S rRNA gene sequence similarity indicated that most closely related to Tabrizicola sediminis DRYC-M-16T, sharing 97.62 % with strain. belonged genus Tabrizicola, which...
A novel Gram-stain-negative, obligately aerobic, non-motile and coccus-shaped bacterium, designated strain CN1T, was isolated from the intestine of a Korean rockfish, Sebastes schlegelii. The optimum growth condition for CN1T 25 °C, pH 7 0-1 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequences showed that in genus Comamonas nearest type koreensis YH12T with 98.65 sequence similarity. primary cellular fatty acids were summed feature 3 (comprised C16 : 1ω7c and/or 1ω6c), 0 8...
A Gram-stain-positive, facultatively aerobic, spore-forming, oxidase-positive, catalase- and DNase-negative, rod-shaped motile bacterial strain, AR23208T, was isolated from the gut of a cinereous vulture (Aegypius monachus), collected at Seoul Grand Park Zoo (Republic Korea). Strain AR23208T grew optimally 25-30 °C, pH 7 in absence NaCl. Phylogenetic analysis revealed that strain shared 98.2 97.1 % 16S rRNA gene sequence similarity with Tumebacillus algifaecis THMBR28T...
A novel Gram-stain-negative, motile, aerobic and rod-shaped alphaproteobacterium, designated strain KHS03T, was isolated from the intestinal tract of a Japanese flying squid, Todarodes pacificus, which collected East Sea, Korea. The new isolate shared 97.4 % 16S rRNA gene sequence similarity with Sedimentitalea nanhaiensis NH52FT. grew optimally at 25 °C pH 7 in presence 1-2 (w/v) NaCl, had an absolute requirement sodium ions for growth. major cellular fatty acid C18 : 1ω7c. primary...
Kushneria konosiri X49T is a member of the Halomonadaceae family within order Oceanospirillales and can be isolated from salt-fermented larval gizzard shad. The genome K. reported here provides genetic basis for its halophilic character. Diverse genes were involved in salt-in -out strategies enabling adaptation to hypersaline environments. Due resistance high salt concentrations, research will contribute improvement environmental biotechnological usage by enhancing understanding osmotic...
A novel Gram-stain-negative, aerobic, rod-shaped, reddish-orange-coloured, gliding bacterial strain, designated L12M1T, was isolated from the gut of Korean scallop, Patinopecten yessoensis. Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain L12M1T formed a monophyletic clade with strains in genus Flammeovirga and showed highest similarity to kamogawensis YS10T (98.66 %). The major cellular fatty acids were iso-C15 : 0 C20 4ω6,9,12,15c. predominant isoprenoid quinone...
A novel, Gram-stain-positive, non-spore-forming, facultatively anaerobic bacterium, designated strain H21T32 T , was isolated from the faeces of an Oriental stork, Ciconia boyciana . Cells formed cocci grouped in pairs, tetrads or conglomerates, and colonies on solid medium were pale yellow. Strain belonged to genus Jeotgalibaca family Carnobacteriaceae order Lactobacillales class Bacilli The 16S rRNA gene sequences showed 97.06–97.34, 96.17–96.31 95.93–96.07 % similarity type strains...
ABSTRACTBackground The prevalence of Parkinson's disease (PD) has increased steadily with the increase elderly population. PD may influence dietary intake and quality, gut microbiome composition. present study examined differences in quality between patients controls according to sex. In addition, we assessed composition.Methods This cross-sectional was conducted at A Medical Center, Seoul, South Korea. severity, swallowing function, olfactory constipation status were by a skilled nurse....
A novel Gram-stain-positive, non-motile, non-spore-forming, coccobacillus-shaped, strictly aerobic bacterium, designated strain H23T48T, was isolated from the faecal sample of an oriental stork collected Seoul Grand Park Zoo in Seoul, Republic Korea. Optimal growth H23T48T observed at 30-37 °C, pH 8 and with 3 % (w/v) NaCl. 16S rRNA gene sequence-based phylogenetic analysis revealed that closely related to genus Flaviflexus, 97.0 96.7 sequence similarities Flaviflexus salsibiostraticola...
A novel coccus-shaped, Gram-stain-positive, non-motile and aerobic bacterium, designated strain NSG39T, was isolated from the intestine of a Korean rockfish, Sebastes schlegelii. Phylogenetic analysis based on 16S rRNA gene sequences indicated that newly NSG39T closely related to Tessaracoccus flavus RP1T (98.0 %). The isolate grew at 15-37 °C, pH 7-9 0-4 % (w/v) salinity, with optimal growth 30 8 0 salinity. cell wall organism contained ll-diaminopimelic acid as diagnostic diamino acid,...