- Thyroid Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Photoacoustic and Ultrasonic Imaging
- Vascular Tumors and Angiosarcomas
- Thyroid and Parathyroid Surgery
- Advanced X-ray and CT Imaging
- Breast Lesions and Carcinomas
- Viral-associated cancers and disorders
- Uterine Myomas and Treatments
- Oral and Maxillofacial Pathology
- Endometrial and Cervical Cancer Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Sarcoma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Kruppel-like factors research
- Diabetes Treatment and Management
- Head and Neck Anomalies
- Salivary Gland Tumors Diagnosis and Treatment
- Underwater Vehicles and Communication Systems
- Head and Neck Surgical Oncology
- Medicinal Plant Pharmacodynamics Research
- Infrared Thermography in Medicine
- Pituitary Gland Disorders and Treatments
- Advanced MRI Techniques and Applications
Army Medical University
2025
Dalian Polytechnic University
2024
Union Hospital
2023
Jilin University
2023
University of Chinese Academy of Sciences
2021-2022
Shaoxing People's Hospital
2009-2021
Zhejiang University
2019-2021
Boehringer Ingelheim (United States)
2021
Mindray (China)
2021
Zunyi Medical University
2020
Rationale & ObjectiveBenefits of sodium-glucose cotransporter 2 inhibitors on kidney outcomes have been demonstrated in clinical trials. Among patients with type diabetes and established cardiovascular (CV) disease enrolled the EMPA-REG OUTCOME study (ClinicalTrials.gov identifier NCT01131676), empagliflozin added to standard care (SOC) reduced risk incident or worsening nephropathy compared SOC alone. This analysis evaluated cost-effectiveness versus alone subpopulation diabetic (DKD) from...
Rationale: The irreversible damage of renal fibrosis has been widely recognized as a critical factor in the progression chronic kidney disease (CKD) to end-stage failure. This necessitates investigation into its precise mechanisms. Dual-specificity phosphatase 1 (DUSP1), regulator mitogen-activated protein kinase (MAPK) pathways, is linked diseases such cancer and immune disorders, but role unclear. study aimed clarify DUSP1 fibrosis, identify intrinsic mechanisms involved, provide...
Synopsis for table of contents An exceptional number synchronous MTC/PTC in the same thyroid gland is presented. This may be most numerous case series reported literature. Synchronous PTC/MTC were classified into 4 subtypes and clinical pathological aspects as well results are Background objectives The occurrence multiple neoplastic processes unusual. We investigated clinicopathological features 30 medullary carcinomas (MTC) association with papillary (PTC). Method Retrospective analysis...
We conduct a study in developing and validating four MRI-based radiomics models to preoperatively predict the risk classification of gastrointestinal stromal tumors (GISTs). Forty-one patients (low-risk = 17, intermediate-risk 13, high-risk 11) underwent MRI before surgery between September 2013 March 2019 this retrospective study. The Kruskal-Wallis test with Bonferonni correction variance threshold was used select appropriate features, Random Forest model (three model) features among...
Olfactory neuroblastoma (ONB) is an ectodermal malignant tumor originating from the olfactory nerve epithelium of nasal cavity and paranasal sinus. a rare cancer, with estimated incidence 0.4 per million. often occurs in top or near lateral wall middle turbinate, which accounts for approximately 3% to 5% sinus tumors. primarily nasopharynx tends be misdiagnosed as nasopharyngeal carcinoma. Herein, we presented case ONB recurrent by lymph node metastasis both sides neck 14 months after...
Abstract Background As thyroid fine needle aspiration (FNA) shows a certain limitation in the diagnosis of conventional smears, novel approaches like liquid-based cytology (LBC) have been gradually applied recently. Studies shown difference between smears (CSs) and on (FNAC) diagnosis, but impacts different preparation (LBP) methods, including membrane-based sedimentation, are still not clear. In this study, effects prepared by methods cytological interpretation were studied. Methods A total...
Abstract Background To investigate value of the quantitative perfusion parameters dynamic triple-phase enhanced CT in differential diagnosis pulmonary lesions, and explore correlation between lung cancer with microvessel density (MVD) vascular endothelial growth factor (VEGF). Methods 73 consecutive patients lesions who successfully underwent pre-operative examination received a final by postoperative pathology or clinical follow-up. The cases were divided into malignant benign groups...
A good predictive model requires patient participation in prognostic counseling and subsequent clinical follow-up. We aimed to construct validate a nomogram for predicting overall survival (OS) patients with follicular thyroid cancer (FTC) after thyroidectomy.This was retrospective observational study. screened 802 initially diagnosed FTC from the Surveillance Epidemiology End Results (SEER) database between 2010 2015. Then were all divided into training set validation randomly at ratio of...
Abstract Background To explore if the quantitative perfusion histogram parameters of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) correlates with expression PTEN, P-Akt and m-TOR protein in lung cancer. Methods Thirty‐three patients 33 lesions who had been diagnosed cancer were enrolled this study. They divided into three groups: squamous cell carcinoma (SCC, 15 cases), adenocarcinoma (AC, 12 cases) small (SCLC, 6 cases). Preoperative (conventional DCE-MRI) was performed on...
A good predictive model requires patients to attend consultations for prognosis and subsequent clinical follow up. The aim of the present study was build a nomogram chart with independent prognostic factors thyroid cancer (TC) total thyroidectomy.This retrospective, observational study. Data were collected from Surveillance, Epidemiology, End Results (SEER) database approved by institutional review board our institution. In total, 11,614 TC after thyroidectomy selected 2010 2015. We divided...
Objective The patient monitors were used to explore the alarm actuality in a ICU and NICU investigate awareness reaction of medical staff alarms. Methods A series surveys interviews taken acquire clinicians' feelings attitudes monitoring researchers scheduled track alarms with annotations, collect data using central system. Results total 235 387 67 783 occurred respectively. average rate was about 142 alarms/patient-day 96 NICU. Conclusions There remains fatigue NICU, main reason is large...
In the traditional grinding process, brittle materials such as glass-ceramics have great problems of outlet stress concentration and edge collapse. order to solve problem collapse at hard in process axial hole machining, a simulation model ultrasonic-assisted machining was established by finite element method, influence geometric parameters wall thickness, fillet chamfer on is analyzed, optimized tool are obtained. The experiments were carried out five-axis center with tool, size observed....
Background: Identification of the Aortic dissection (AD) at baseline plays a crucial role in clinical practice. Non-contrast CT scans are widely available, convenient, and easy to perform. However, detection AD on non-contrast by radiologists is lack sensitivity suboptimal present. Methods: A total 452 patients underwent aortic angiography (CTA) were enrolled retrospectively from two medical centers China form an internal cohort (341 patients, 139 AD, 202 non-AD) external testing (111 46 65...
Objective: To explore the efficacy of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) histogram molecular index, apparent diffusion coefficient (ADC) in different types lung cancer and their correlation with Ki-67. Methods: A total 33 cases patients confirmed by pathology Shaoxing People's Hospital from March 2017 to 2018 were collected, 28 males 5 females aged 50-85 years old, including 15 squamous cell carcinoma, 12 adenocarcinoma, 6 small carcinoma. All performed DCE-MRI...
Currently, the curative effects of polypeptide drugs are often restricted due to short
:To explore the value of quantitative perfusion histogram parameters dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in pathological classification uterine leiomyoma and its correlation with Ki-67 protein expression. Thirty five patients confirmed by operation pathology at Shaoxing People's Hospital from October 2015 to September 2017 were analyzed retrospectively,including 15 cases ordinary type,8 cellular type 12 degenerative type. All examined pelvic DCE-MRI before...
Objective To explore the role of bisphenol A in ovarian cancer cell migration and its molecular mechanism. Methods The human OVCAR-3 line was chosen as research materials this study. The 8 μm pore size Boyden chambers QMC Chemotaxis Cell Migration Assay were adopted for analysis. molecules involved measured by real-time fluorescent quantitative PCR, western blot SensoLyte 490 kits. mechanism induced studied inhibition ERK1/2 PI3K using their corresponding...