- Traditional Chinese Medicine Studies
- Angiogenesis and VEGF in Cancer
- Extracellular vesicles in disease
- Traditional Chinese Medicine Analysis
- Biological Activity of Diterpenoids and Biflavonoids
- Immune cells in cancer
- Metabolomics and Mass Spectrometry Studies
- Toxin Mechanisms and Immunotoxins
- Immunotherapy and Immune Responses
- Nanoplatforms for cancer theranostics
- Cytokine Signaling Pathways and Interactions
- Natural product bioactivities and synthesis
Guangzhou Eighth People's Hospital
2024
Guangzhou Medical University
2024
Fujian Medical University
2022-2024
Education Department of Fujian Province
2024
Fujian Provincial Cancer Hospital
2023
Abstract Cancer immunotherapy offers significant clinical benefits for patients with advanced or metastatic tumors. However, immunotherapeutic efficacy is often hindered by the tumor microenvironment's high redox levels, leading to variable patient outcomes. Herein, a therapeutic liposomal gold nanocage (MGL) innovatively developed based on photo‐triggered hyperthermia and releasable strategy combining glutathione (GSH) depletion remodel immune microenvironment, fostering more robust...
Background. Lymphatic metastasis is a common phenomenon of cervical cancer. Tumor necrosis factor-α (TNF-α) was found to be closely associated with lymphatic cancer metastasis. However, the mechanism through which TNF-α regulates in remains unclear. Methods. In this study, cells were cultured Dulbecco’s modified Eagle’s medium (DMEM) or without for 48 h, and then corresponding conditional (CM-TNF-α CM) collected. The level vascular endothelial growth factor (VEGFC) CM detected using an...
Selaginella doederleinii Hieron is a traditional Chinese medicinal herb widely used to treat different cancers. Previously, we showed that the total bioflavonoid extract of S. (TBESD) exhibits anti-carcinogenic activities both in vitro and vivo. However, plasma protein binding pharmacokinetics parameters TBESD remain unclear. To investigate binding, tissue distribution, excretion TBESD, rats were administered single dose (600 mg/kg) intragastrically distribution components determined by...
Yupingfeng powder (YPF) is a classic traditional Chinese medicine prescription with long history of clinical application. However, there consensus on the efficacy YPF in prevention and treatment influenza, underlying pharmacological mechanisms functional substances have not been thoroughly investigated.