- Research on Leishmaniasis Studies
- Photodynamic Therapy Research Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Synthesis and biological activity
- thermodynamics and calorimetric analyses
- Laser Applications in Dentistry and Medicine
- CRISPR and Genetic Engineering
- Pluripotent Stem Cells Research
- Inflammasome and immune disorders
- Burkholderia infections and melioidosis
- Fish biology, ecology, and behavior
- Bioactive Compounds and Antitumor Agents
- bioluminescence and chemiluminescence research
- Clostridium difficile and Clostridium perfringens research
- Venomous Animal Envenomation and Studies
- Healthcare during COVID-19 Pandemic
- Marine and fisheries research
- Viral gastroenteritis research and epidemiology
- Public Health in Brazil
- Healthcare and Venom Research
- Rural Development and Agriculture
- Connexins and lens biology
- Antimicrobial Peptides and Activities
- Electrochemical Analysis and Applications
- Phytochemical compounds biological activities
Universidade Vila Velha
2020
Universidade Federal de Santa Catarina
1998-2018
Universidade do Vale do Paraíba
2007-2015
State University of Norte Fluminense
2001-2004
Objective: The objective of this work was to investigate the anti-inflammatory effects low-level laser therapy, applied at different wavelengths (660 and 684 nm), on cytokine mRNA expression after carrageenan-induced acute inflammation in rat paw. Background Data: Low-level therapy (LLLT) has been observed reduce pain inflammatory disorders. However, little is known about mechanisms behind effect or whether it wavelength-specific. Materials Methods: test sample consisted 32 rats divided into...
A leishmaniose é uma doença infecciosa, não-contagiosa de caráter zoonótico, causada por vários tipos protozoários do gênero Leishmania, podendo apresentar a infecção no organismo vivo diferentes maneiras, sendo as mais conhecidas forma tegumentar e visceral. Calcula-se que prevalência mundial esteja em torno 12 milhões, acometendo 80 países com estimativa 400.000 casos novos da ano. O objetivo desta pesquisa foi o analisar através retrospectiva, abordagem descritiva quantitativa situação...
Cutaneous leishmaniasis is an infectious disease caused by protozoans of the genus Leishmania, which transmitted through bite hematophagous insects Lutzomyia. This study aimed at testing in vitro phototoxic effect aluminum phthalocyanine tetrasulfonate (AlPcS4) on viability Leishmania major and braziliensis. Stationary phase promastigote forms were treated with AlPcS4 1.0 µM 10.0 incubated for one hour. Then 659 nm laser was applied 5 10 J/cm². Parasite determined differential count using...
In this study, phthalocianato[bis(dimethylaminoethanoxy)] silicon (NzPC) was loaded onto gelatin nanoparticles functionalized with polyelectrolytes (polystyrene sulfonate/polyallylamine hydrochloride) by layer-by-layer (LbL) assembly for photodynamic therapy (PDT) application in promastigote form of Leishmania amazonensis treatment. The process yield, and encapsulation efficiency were 80.0% ± 1.8 EE = 87.0% 1.1, respectively. polyelectrolytic (PGN) had a mean diameter 437.4 72.85 nm, narrow...
We studied the karyotypes of three hybrid clones mouse embryonic stem cells and murine splenocytes (two having near diploid one tetraploid chromosome numbers) characteristics their differentiation during formation embryoid bodies. The X originating from may be lost in hybrids with a number reprogramming "somatic" occur. morphological data we obtained using light electron microscopy revealed correlation between karyotype constitution At beginning development, bodies derived already showed an...
Snake venoms are toxic to a variety of cell types. However, the intracellular damages and death fate induced by venom unclear. In present work, action South American rattlesnake Crotalus durissus terrificus on CHO-K1 line was analyzed. The cells were incubated with C. d. (10, 50 100g/ml) for 1 24 hours, structural alterations actin filaments, endoplasmic reticulum nucleus assessed using specific fluorescent probes agarose gel electrophoresis DNA fragmentation. Significant changes observed in...
American cutaneous leishmaniasis (ACL) is an infectious disease caused by protozoans of the genus Leishmania. The treatment may consist pentavalent antimonials or pentamidine and amphotericin. However, these treatments are extremely aggressive. Photodynamic antimicrobial chemotherapy (PACT) involves same mechanism photodynamic therapy which associates a photosensitizer with oxygen light source generating photochemical reaction leading to cell death. aim this study was verify potential use...
A total of 1257 caprellids, mostly females, were collected, from Februruy to