- Interconnection Networks and Systems
- Parallel Computing and Optimization Techniques
- Embedded Systems Design Techniques
- RNA Interference and Gene Delivery
- Virus-based gene therapy research
- Gene expression and cancer classification
- Cell Adhesion Molecules Research
- Neural Networks and Applications
- Bioinformatics and Genomic Networks
- Gene Regulatory Network Analysis
- Advanced biosensing and bioanalysis techniques
- Platelet Disorders and Treatments
- Arsenic contamination and mitigation
- Intensive Care Unit Cognitive Disorders
- Pluripotent Stem Cells Research
- Distributed and Parallel Computing Systems
- Real-Time Systems Scheduling
- Carcinogens and Genotoxicity Assessment
- Scientific Computing and Data Management
- Nosocomial Infections in ICU
- Animal Genetics and Reproduction
- Monoclonal and Polyclonal Antibodies Research
- CRISPR and Genetic Engineering
- Face and Expression Recognition
- Sepsis Diagnosis and Treatment
Soochow University
2023
Indiana University – Purdue University Indianapolis
1996-2012
University of Indianapolis
2007-2009
Indiana University
2007
Indiana University School of Medicine
1996-1998
Riley Hospital for Children
1996-1998
Howard Hughes Medical Institute
1996
Amgen (United States)
1996
Fibronectin (FN), an extracellular matrix protein, is involved in the adhesion and migration of hematopoietic cells has been shown to enhance retroviral gene transfer into primitive by co-localization target retrovirus when used as a substrate vitro. We have previously found that mouse stem could be transduced on FN fragment included recognition sequence Arg-Gly-Asp (RGD), suggesting may express integrin very late antigen (VLA)-5. To address this, we investigated binding human recombinant...
Gene clustering, the process of grouping related genes in same cluster, is at foundation different genomic studies that aim analyzing function genes. Microarray technologies have made it possible to measure gene expression levels for thousand simultaneously. For knowledge be extracted from datasets generated by these technologies, presented a scientist meaningful way. clustering methods serve this purpose. In paper, hybrid approach based on self-organizing maps and particle swarm...
Abstract Sepsis is a dysregulated host response to infection that can lead life‐threatening organ failure. Circulating bacterial toxins, termed pathogen‐associated molecular patterns (PAMPs), and excess cytokines produced by the immune system play key role in progress into Yet, no therapy available effectively remove these PAMPs from circulation or block their action. Macrophage membrane coatings possess natural blood compatibility, ideal for coating of adsorbent surfaces extracorporeal...
Gene clustering, the process of grouping related genes in same cluster, is at foundation different genomic studies that aim analyzing function genes. Microarray technologies have made it possible to measure gene expression levels for thousands simultaneously. For knowledge be extracted from datasets generated by these technologies, presented a scientist meaningful way. clustering methods serve this purpose. In paper, hybrid approach based on self-organizing maps and particle swarm...
Due to rapid technology advance, multiprocessor system-on-chips (MPSoCs) are likely become commodity computing platforms for embedded applications. In the future, it is possible that an MPSoC equipped with a large number of processing elements as well on-chip resources. The management these faces many challenges, among which deadlock one most crucial issues. This paper presents novel hardware-oriented detection algorithm suitable current and future MPSoCs. Unlike previously published methods...
This article describes a novel parallel multi-unit resource deadlock detection algorithm (MDDA) and its hardware implementation (MDDU). The contributions are (i) the first O(1) detection, (ii) reduced O(min(m, n)) preparation, where m n number of processes resources, respectively, (iii) support for resources. n)), previously O(mtimesn), is achieved by performing all searches sink nodes each every in over two matrices representing allocations as well other auxiliary matrices. MDDU provides...
Given the projected dramatic increase in number of processors and resources a system-on-a-chip, quadratic likelihood deadlock is predicted due to complex system behavior. To deal with this issue, we here present novel parallel hardware-oriented detection algorithm O(1) O(min(m,n)) preparation, where m n are numbers processes resources, respectively. Our contributions (i) first hardware implementation (ii) new algorithmic method achieving overall run-time complexity. We implement our Verilog...
This paper introduces a novel O(1) parallel deadlock detection approach for multi-unit resource system-on-a-chips (SoCs), inspired by Kimpsilas method in as well Shiupsilas processing. Our contributions are (i) the first hardware and (ii) O(min(m, n)) preparation, both systems, where m n number of processes resources, respectively. n)), previously O(m times n), is achieved performing all searches sink nodes each every over matrix representing allocations other auxiliary matrices. experiments...
Building a high-quality bioinformatics workflow needs not only good biology knowledge, but also extensive knowledge of existing online services. To facilitate this task, we present novel approach automatic composition in SIBIOS system. Our regards the task as planning problem, and uses Graphplan solution planner. We extended to allow users specify particular services that they want use workflow, well order those are used. Automatically generated workflows used baseline for researchers, be...
In this article, a brand new method of determining deadlock is presented. Most previous detection methods are algorithmic in the sense that they usually leverage some forms Resource Allocation Graph (RAG) representations and then algorithms devised to manipulate such order detect using information contained graph. Different from all methods, proposed actualizes RAG with digital circuit uses it as token-transmitting network. By supplying special input signals (tokens) network observing output...
This article proposes a novel parallel, hardware-oriented deadlock detection algorithm for multiprocessor system-on-chips. The proposed takes full advantage of hardware parallelism in computation and maintains information needed by through classifying all resource allocation events performing class specific operations, which together make the overall run-time complexity new method O(1). We implement Verilog HDL demonstrate simulation that each invocation at most four clock cycles hardware.