Dialogue summarization extracts useful information from a dialogue. It helps people quickly capture the highlights of dialogue without going through long and sometimes twisted utterances. For customer service, it saves human resources currently required to write summaries. A main challenge is design mechanism ensure logic, integrity, correctness In this paper, we introduce auxiliary key point sequences solve problem. sequence describes logic summary. our training procedure, acts as an label....

The Golgi apparatus lies at the heart of secretory pathway where it is required for trafficking and cargo modification. Disruption architecture function has been widely observed in neurodegenerative disease, but whether dysfunction causal with regard to process, or simply a manifestation neuronal death, remains unclear. Here we report that targeted loss golgin GM130 leads profound neurological phenotype mice. Global KO mouse results developmental delay, severe ataxia, postnatal death. We...

Abstract The rechargeable aqueous metal‐ion battery (RAMB) has attracted considerable attention due to its safety, low costs, and environmental friendliness. Yet the poor‐performance electrode materials lead a feasibility of practical application. A hybrid (HAB) built from with selective cation channels could increase applicability thus enlarge application RAMB. Herein, we construct high‐voltage K–Na HAB based on K 2 FeFe(CN) 6 cathode carbon‐coated NaTi (PO 4 ) 3 (NTP/C) anode. Due unique...

Abstract Globozoospermia is a common reproductive disorder that causes male infertility in humans, and the malformation or loss of acrosomes prominent feature this disease. Although acrosome thought to be derived from Golgi apparatus, detailed molecular mechanisms remain unclear. GM130 cis -side localized matrix protein,whereas physiological functions protein elusive. Here we showed inactivation GM130-caused mouse model. The primary defects were absence acrosomes, round sperm heads, aberrant...

Abstract B cells are the center of humoral immunity and produce Abs to protect against foreign Ags. cell defects lead diseases such as leukemia lymphomas. Histone arginine methylation is important for regulating gene activation silencing in cells. Although process commonly exists mammalian cells, its roles unknown. To explore effects aberrant histone on we generated mice with a cell–specific knockout PRMT7, member methyltransferases that mediate histones. In this article, showed loss PRMT7...

Abstract Aqueous potassium‐ion batteries have demonstrated huge potential in the field of energy storage, owing to their low cost, environmental friendliness, and high safety, yet with poor cycling stability rate capability. Here, potassium Prussian white analogues (K‐PW) different gradients crystallinity size been synthesized by controlling acidity hydrothermal environment. The as‐synthesized K 1.93 Fe[Fe(CN) 6 ] 0.97 ⋅ 1.82H 2 O nanoparticles deliver considerable reversible capacities 142...

Abstract During germ cell development, epigenetic modifications undergo extensive remodeling. Abnormal usually result in loss and reproductive defect. Prmt5 (Protein arginine methyltransferase 5) encodes a protein which has been demonstrated to play important roles development during embryonic stages. In the present study, we found that was also abundantly expressed male cells after birth. Inactivation of this gene by crossing with Stra8-Cre transgenic mice resulted spermatogenesis. Further...

Abstract Ion conduction refers to a conductive process consisting of the directional motion ions driven by an electric field, which is one most important issues for further improvement batteries in current and foreseeable future. In order better understand phenomena alkali metal‐ion (Li + /Na /K ) (AMIBs) achieve technological breakthroughs, recent studies on ion diffusion electrode materials electrolytes AMIBs are investigated. Three aspects factors that affecting mainly listed: (i) crystal...

Femtosecond and nanosecond laser ablation was studied for the analysis of alloy samples by inductively coupled plasma mass spectrometry (ICP-MS). Two series standards from National Institute Standards Technologies (NIST) were used to establish calibration graphs (NIST 625-629 NIST 1737-1741). The quality (correlation coefficient, sensitivity confidence intervals) compared with 266 nm wavelength each laser. Accuracy precision established these determining lead (208Pb) concentration when two...

NAND-based solid-state disks (SSDs) are known for their superior random read/write performance due to the high degrees of multi-chip parallelism they exhibit. Currently, as chip density increases dramatically, fewer 3D NAND chips needed build an SSD compared previous generation chips. As a result, SSDs can be made more compact. However, this decrease in number also results reduced overall throughput, and prevents from being widely-adopted. We analyzed 600 storage workloads, our analysis...

A photocatalytic synthesis of difluoromethylated selenides from selenosulfonates is described here. Bench-stable difluoromethyl phosphonium salt [Ph3PCF2H]Br reacts smoothly with to give a series functionalized in moderate good yields via radical process. This protocol free stoichiometric base and reductant, has tolerance functional groups, successful late-stage modification bioactive molecules, which provides facile access molecules pharmaceutical relevance.

This letter proposes a new approach to making network selection simple yet effective. Under consideration is heterogeneous environment where mobile user roams within two-tier architecture over different radio access technologies. Allowing for multiple determinants, we design scheme equipment deduce whether handoff imminent by fusing several metrics-received signal strength, data rate, and latency. Our method harnesses strengths of fuzzy logic while maintaining lower computational complexity...

Due to the rapid growth of event-based social networks (EBSNs), event recommendation which helps users find their preferred events has become a popular topic. Different from movies or books in conventional problem, usually have lifetimes and almost all be recommended are upcoming, brings severe cold start problem. To achieve better performance, we formulates multiple interactions among users, events, groups locations into an unified framework propose collective pairwise matrix factorization...

The adoption of 3D NAND has significantly increased the SSD density; however, density-increasing techniques, such as extensive stacking cell layers, can amplify read disturbances and shorten lifetime. From our lifetime-impact characterization on 8 state-of-the-art SSDs, we observe that TLC/QLC SSDs be worn-out by low read-only workloads within their warranty period since a huge amount disturbance-induced rewrites are performed in background. To understand alternative disturbance mitigation...

Due to its several attractive benefits such as shock resistance, energy efficiency, and space-efficient form factor, flash memory is now applied a wide range of electronics. Typically, since write requests are harmful the health memory, some flash-based storage devices tend be deployed for read-intensive applications recently. However, technology node keeps going, read disturbance becomes worsening problem in memory. Even under pure workload, often needs refresh disturbed data, which brings...

This paper proposes a novel design for highly area efficient FPGA-based TDC (time to digital converter) IP (intelligent property) with resolution less than 30 ps. To avoid the unpredictable internal place and route (P&R) delay, modified ring oscillator is presented. By integrating gates delay P&R by combining schematic VHDL codes, can generate predictable stable module built in Xilinx FPGA

In mammals, germ cells undergo massive epigenetic remodeling during fetal development. However, the physiological functions of modification in cell development remain unclear. this study, we found that protein arginine methyltransferase 5 (Prmt5) was abundantly expressed both male and female gonads. Deletion Prmt5 by crossing with Tnap-Cre mice resulted depletion adult mice. Germ loss first observed between Embryonic Days 12.5 13.5 (E12.5 E13.5), very few these remained at birth. Oct4, Sox2,...