Abstract Chalcogen-containing compounds have received considerable attention because of their manifold applications in agrochemicals, pharmaceuticals, and material science. While many classical methods been developed for preparing organic sulfides, most them exploited the transition-metal-catalyzed cross-couplings aryl halides or pseudo with thiols disulfides, harsh reaction conditions usually being required. Herein, we present a user-friendly, nickel-catalyzed reductive thiolation...

A novel and efficient approach for the selenium functionalization of indoles was developed with powder as source, catalyzed by 2,2,6,6-tetramethylpiperidinooxy (TEMPO) employing O2 green oxidant. This protocol provides a practical route synthesis 3-selenylindole derivatives has advantages readily available starting materials, mild reaction conditions, wide scope substrates. Electron spin-resonance (ESR) studies reveal that involves formation nitrogen-centered radicals via oxidation in situ...

A facile and novel method for the synthesis of functionalized 1,2,4-selenadiazoles through aerobic radical-cascade cyclization isocyanides, selenium imidamides is established.

An efficient method for the construction of 2-aminobenzo[<italic>d</italic>][1,3]selenazines under metal-free conditions was established.

A regioselective rhodium-catalyzed thiolation of N-tosyl acrylamides with readily available disulfides has been developed. Through N-tosylamide-assisted activation the alkenyl C(sp2)–H bond, a series (Z)-alkenyl sulfides were constructed in moderate to excellent yields good tolerance functional groups. Turnover numbers (TONs) up 7100 obtained utilizing 0.01 mol % RhIII catalyst. In addition, diphenyl diselenide was also successfully applied this reaction for construction (Z)-β-alkenyl...

The simple inorganic rhodium salt RhCl3·3H2O was used as a catalyst to achieve the thiolation of acrylic acids, with series (Z)-alkenyl sulfides being obtained exclusively. It is noteworthy that [Cp*RhCl2]2 not efficient in this strategy. Furthermore, products could be transformed conveniently into biologically and pharmacologically useful thioflavones.

A photocatalytic synthesis of difluoromethylated selenides from selenosulfonates is described here. Bench-stable difluoromethyl phosphonium salt [Ph3PCF2H]Br reacts smoothly with to give a series functionalized in moderate good yields via radical process. This protocol free stoichiometric base and reductant, has tolerance functional groups, successful late-stage modification bioactive molecules, which provides facile access molecules pharmaceutical relevance.

Abstract Polyethersulfone (PES) membranes using different evaporation periods were fabricated by the phase‐inversion method. Pervaporation experiments conducted for chloroform/water mixtures to determine selectivity of PES membranes. It was found that chloroform could be concentrated in permeate from binary feed prepared longer periods, and pervaporation reversed shorter periods. This study also showed adding surface‐modifying macromolecules (SMM) up 1 wt % into casting solution, enrichment...

A new and facile approach toward highly functionalized carbamimidoseleknoates was developed through the copper(I)-catalyzed ligand-promoted four-component reaction of isocyanides, selenium, amines, aryl iodides. The constructed a range organoselenium compounds containing an isoselenourea skeleton with potential bioactivity directly from selenium powder. simplicity method broad diversity substrates also highlight this work.

To improve the alkaline stability of anion exchange membranes (AEMs) based on conventional poly(ether ketone/sulfone) backbones, two novel poly(phenylene-<italic>co</italic>-arylene ether ketone) (PPAEK) ionomers with a quaternary ammonium (QA-) or imidazolium (IM-) group were prepared.

A facile synthesis of secondary selenocarbamates through metal-free multicomponent reactions isocyanides, selenosulfonates and water is reported here. The reaction easy to handle proceeds smoothly under mild conditions.

New practical synthesis of 2-amino-1,3-selenazole with transition metal-free multicomponent reaction is reported here. A series derivatives were afforded by the nucleophilic addition amines to isoselenocyanate formed in situ, followed Michael and aromatization. The products isolated from moderate excellent yields.

The aim of the work was to determine interactions a set anti-cancer compounds with bovine serum albumin (BSA) using ProteOn XPR36 array biosensor and molecular docking studies. results revealed that total six compounds: gallic acid, doxorubicin, acteoside, salvianolic acid B, echinacoside, vincristine were able reversibly bind immobilized BSA. sensorgrams these globally fit Langmuir 1:1 interaction model for binding kinetics analysis. There significant differences in their affinity BSA,...

Abstract A systematic investigation has been conducted to demonstrate applicability of reverse osmosis (RO) fractionation organic liquid mixtures by laboratory‐prepared cellulose acetate butyrate (CAB) and aromatic polyamid (PA) membranes. The determination preferential sorption was also using chromatography technique. It found that applicable the mixtures. component binary mixture is enriched in membrane permeate can be predicted considering Stokes' radius for each constituent feed mixtre.

A facile synthesis of N-(carboselenoate) benzimidazolones through metal-free reactions ortho-diisocyanoarenes with selenosulfonates is reported here. The desired products are obtained in moderate to good yields functional group compatibility. applied the construction 2-benzimidazolone derivatives for first time.

A new efficient approach for the I₂ promoted selenium functionalization of <italic>in situ</italic> generated imidazoheterocycles utilizing aliphatic selenosulfonate as source under transition metal-free conditions is developed.

We assessed the role of protein-coding gene chaperonin-containing TCP1 subunit 6A (CCT6A) in osteosarcoma, as this is currently unknown. Using data from R2 online genomic analysis and visualization application, we found that CCT6A messenger ribonucleic acid (RNA) expression increased osteosarcoma tissue cells. Transfection small interfering RNA into cultured cells revealed knockdown attenuates cell growth, viability, survival, induced apoptosis cycle progression at G0/G1 phases. Moreover,...

Protonation of [RCnRuH(L)(L‘)]+ (RCn = 1,4,7-triazacyclononane and 1,4,7-trimethyl-1,4,7-triazacyclononane; L,L‘ (PPh3)2, dppe, CO,PPh3) produced the corresponding dicationic dihydrogen complexes [RCnRu(H2)(L)(L‘)]2+. TpRuH(dppe) (Tp hydrotris(pyrazolyl)borato) yielded new monocationic complex [TpRu(H2)(dppe)]+. The acidity [RCnRu(H2)(L)(L‘)]2+ [TpRu(H2)(L)(L‘)]+ (L,L‘ CH3CN,PPh3, has been studied. It was found that are more acidic than their Tp Cp counterparts. [MeCnRu(H2)(CO)(PPh3)]2+ to...

d-Pantolactone is a key chiral intermediate for the synthesis of d-pantothenic acid and its derivatives. Biocatalytic kinetic resolution d,l-pantoyl lactone using d-lactonase an efficient route to synthesize d-pantolactone. In this study, we report expression novel TSDL in Escherichia coli host. The recombinant exhibited high hydrolysis activity enantioselectivity toward reaction conditions TSDL-catalyzed d,l-pantolactone was systematically investigated by whole cell biocatalysis. addition,...