A5046528178- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Reproductive System and Pregnancy
- Advanced Vision and Imaging
- Histone Deacetylase Inhibitors Research
- Immune cells in cancer
- Assisted Reproductive Technology and Twin Pregnancy
- Methane Hydrates and Related Phenomena
- Computer Graphics and Visualization Techniques
- Flavonoids in Medical Research
- Cancer-related molecular mechanisms research
- Advanced Image Processing Techniques
- CCD and CMOS Imaging Sensors
- Neurobiology and Insect Physiology Research
- Ovarian function and disorders
- Advanced Fluorescence Microscopy Techniques
- Circular RNAs in diseases
- Hydrocarbon exploration and reservoir analysis
- Cancer Mechanisms and Therapy
- Remote Sensing in Agriculture
- Endometriosis Research and Treatment
- CO2 Sequestration and Geologic Interactions
- Phagocytosis and Immune Regulation
- interferon and immune responses
- Gene Regulatory Network Analysis
China University of Geosciences (Beijing)
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2019-2024
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2024
Shanghai University of Traditional Chinese Medicine
2024
Xi'an Jiaotong University
2021-2022
East China Normal University
2021
Nanjing Drum Tower Hospital
2017-2020
Institut de Médecine de la Reproduction
2019
Nanjing University
2019
Zhejiang University
2019
Extensive electrophysiology studies have shown that many V1 simple cells nonlinear response properties to stimuli within their classical receptive field (CRF) and receive contextual influence from outside the CRF modulating cell's response. Models seeking explain these non-classical (nCRF) effects in terms of circuit mechanisms, input-output descriptions, or individual visual tasks provide limited insight into functional significance properties, because they do not connect full range nCRF...
Background and Aims: Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic under inflammation, play crucial role in liver fibrosis progression. The spleen serves as an extra monocyte reservoir inflammatory conditions; however, the precise mechanisms involvement pathogenesis remain unclear. Approach Results: By splenectomy splenocyte transfusion, it was observed that splenic CD11b + cells accumulated intrahepatically Ly6C lo MoMFs to exacerbate CCl 4 ‐induced fibrosis....
Sparse approximation is a hypothesized coding strategy where population of sensory neurons (e.g. V1) encodes stimulus using as few active possible. We present the Spiking LCA (locally competitive algorithm), rate encoded Neural Network (SNN) integrate and fire that calculate sparse approximations. The designed to be equivalent nonspiking LCA, an analog dynamical system converges on ℓ 1 -norm approximations exponentially. show firing same solution with error inversely proportional sampling...
Natural gas hydrates (shortened as hydrates) are expected to be a prospective alternative traditional fossil energies. The main strategy of exploring is achieved by dissociating solid into and water with the depressurization method. However, we have little knowledge on changes in heat energy, which implicit essences compared explicit temperature. Thus, this study for first time investigates evolutionary patterns energy during hydrate dissociation, fully coupled...
There is still much unknown regarding the computational role of inhibitory cells in sensory cortex. While modeling studies could potentially shed light on critical played by inhibition cortical computation, there a gap between simplicity many models coding and biological complexity subpopulation. In particular, do not respect that must be implemented separate subpopulation, with those interneurons having diversity tuning properties characteristic E/I cell ratios. this study we demonstrate...
Abstract Accumulating findings reveal that long noncoding RNAs (lncRNAs) as crucial regulatory molecules serve vital functions in the progression of hepatocellular carcinoma (HCC). This study aims to investigate biological roles and mechanisms lncRNA HOXD cluster antisense RNA 1 (HOXD‐AS1) HCC cells based on transcriptome analysis. The Cancer Genome Atlas data analysis experimental validation showed HOXD‐AS1 was increased tissues/cell lines positively relevant histologic grade. subcellular...
Hepatocellular carcinoma (HCC) is the most common type of hepatic malignancies with high mortality and poor prognosis. Baicalein, one major bioactive flavonoids isolated from Scutellaria baicalensis Georgi, which reported to have anti-proliferation effect in varying cancers, including HCC, whose underlying molecular mechanism still largely unknown. In this study, we found that baicalein significantly inhibited proliferation colony formation, blocked cell cycle, promoted apoptosis HCC cells...
Natural gas hydrates (shorted as hydrates) are expected to be a prospective alternative for traditional fossil energies in the future. The main strategy of exploring is achieved by dissociating solid into and water situ with depressurization method. Many studies have been conducted understand process hydrate dissociation porous media from perspectives temperature, fluid flow, mechanical deformation saturation. However, we few deeper analyses on evolutions heat energy, which implicit essences...
Abstract Homeobox A10 (HOXA10) is a characterized marker of endometrial receptivity. The mechanism by which hCG intrauterine infusion promotes embryo implantation still unclear. This study seeks to investigate whether improves receptivity increasing expression HOXA10. HOXA10 with human chorionic gonadotropin stimulation was analyzed in vitro and vivo. Our results demonstrate that decreased the endometria recurrent failure patients compared healthy control fertile group, also we observed...
As the feature size of semiconductor process is scaling down to 10nm and below, it possible assemble systems with high performance processors that can theoretically provide computational power up tens PLOPS. However, consumption these also rocketing millions watts, actual only around 60% theoretical performance. Today, efficiency sustained have become main foci processor designers. Traditional computing architecture such as superscalar GPGPU are proven be inefficient, there a big gap between...
In this paper, we propose an interpolation-based method for simulating rigid needles in B-mode ultrasound images real time. We parameterize the needle image as a function of position and orientation. collect under various spatial configurations water-tank using guidance robot. Then use multidimensional tensor-product interpolation to simulate with arbitrary poses positions collected images. After further processing, interpolated seed are superimposed on top phantom or tissue backgrounds. The...
Objective: Myeloid-derived suppressor cells (MDSCs) have been described as important immunosuppressive for maternal immune tolerance. The aim of this study was to detect whether there any association between the peripheral blood MDSCs level and in vitro fertilization (IVF) treatment outcomes. Methods: This prospective observational randomly recruited 85 women who underwent IVF from May 2016 June 2016. levels granulocytic MDSC (G-MDSC), monocytic (M-MDSC) their relations outcomes were...
Advances in circulating tumor DNA (ctDNA) analysis for diffuse large B-cell lymphoma (DLBCL) have prompted the evaluation of its utility other non-Hodgkin lymphomas (NHLs), leading to significant insights into potential applications.
Background & Aims: The species diversity of canopy trees is important for the function and service natural forest ecosystems.To be able to formulate reasonable biodiversity conservation strategies, it understand patterns through time.However, development high-precision monitoring at a regional scale slow due limitation in information collection methods.A lot may substantially change climate human disturbance.However, updating these changes cannot done timely manner.In recent years,...
It is still uncertain whether surgical evacuation adversely affects subsequent embryo transfer. The present study aims to assess the influence of on pregnancy outcomes transfer cycle following first trimester miscarriage in an initial vitro fertilization and (IVF-ET) cycle.A total 645 patients who underwent their IVF between January 2013 May 2016 Nanjing Drum Tower Hospital were enrolled. Surgical was performed when products conception retained more than 8 h after medical evacuation....
This study was conducted to evaluate the effects of in ovo feeding (IOF) L-lysine (Lys) on hatchability and development pigeon neonates. At day 13 incubation, fertile eggs were injected with 200 μL sterilized saline (0.75%, SC group), 1% Conc. Lys solution (Lys group, 2.11 mg dissolved saline), controls not (NC group). The results showed that IOF decreased (P < 0.05) compared other groups, whereas hatching time affected among groups. On 14 post-hatch (D14), body weight (BW) squabs received...
While many neural coding models have been proposed for V1, it remains an open question as to which model best describes the diversity of observed response properties. For instance, canonical linear-nonlinear (LN) partially explains some fundamental mechanistic and phenomenological properties but is unable explain nonlinear that are likely associated with keys efficient robust human vision. example, surround suppression one such property in visual stimuli extending beyond classical receptive...
Non-classical receptive field (nCRF) effects include several response properties in V1 neurons not explained by a linear-nonlinear (LN) model, but instead requiring significant interactions between neurons. Using sparse coding model [1,2] and bar grating stimuli, simulated physiology experiments were carried out that replicated nCRF phenomena reported previously neurophysiology experiments. These include: end-stopping [3] (Fig. (Fig.1),1), contrast invariance of orientation tuning [4]...
Liver metastasis is the main cause of cancer-related mortality. During process, circulating carcinoma cells hardly pass through narrow capillaries, leading to nuclear deformation. However, effects deformation and its underlying mechanisms on need further study. Here, it shown that mechanical force-induced exacerbates liver by activating cGAS-STING pathway, which promotes splenocyte infiltration in liver. Mechanical force results rupture envelope with inevitable DNA leakage. Cytoplasmic...
Neurons in the primary visual cortex exhibit a baffling array of tuning properties, often unaccountable by classical linear feedforward model. Specifically, excitatory neurons display number nonlinear effects collectively known as non-classical receptive field (nCRF) [1], and inhibitory have diverse orientation properties [2]. Furthermore, cells outnumber ratio 9:1 [3], yet drives are balanced. Efficient coding models early vision been shown to be able explain key features filtering [4] some...
The training of ultrasound guided interventional procedures could benefit from simulators that synthesize realistic-looking B-mode images tissue and tools, such as the needle. For a prostate brachytherapy simulator in particular, both needle seed need to be synthesized. In this thesis, we propose an interpolation-based method for simulating real time. We parametrize or image function its position orientation. collect under various spatial configurations water-tank using guidance robot. Then...
Abstract Lung cancer represents a significant public health concern worldwide. typically receives diagnosis at late stage, leading to generally unfavourable prognosis. Additionally, traditional treatments frequently fail in cases of metastatic lung cancer. However, targeted therapy has advanced considerably the management cancer, and overcoming drug resistance emerged as hurdle achieving optimal treatment outcomes. As result, there been new trend toward precision for based on changes...