B S Sim

ORCID: 0009-0005-8301-150X
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About
Contact & Profiles
Research Areas
  • Head and Neck Surgical Oncology
  • Vascular Malformations Diagnosis and Treatment
  • Intracranial Aneurysms: Treatment and Complications
  • Hydrogels: synthesis, properties, applications
  • Neurosurgical Procedures and Complications
  • Neuroblastoma Research and Treatments
  • Meningioma and schwannoma management
  • Cerebrospinal fluid and hydrocephalus
  • Spinal Fractures and Fixation Techniques
  • Polymer Surface Interaction Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Neurofibromatosis and Schwannoma Cases
  • Spinal Hematomas and Complications
  • Spine and Intervertebral Disc Pathology
  • Salivary Gland Disorders and Functions
  • Veterinary Orthopedics and Neurology
  • Sinusitis and nasal conditions
  • Corneal Surgery and Treatments
  • Orthopaedic implants and arthroplasty
  • Cervical and Thoracic Myelopathy
  • Sarcoma Diagnosis and Treatment
  • History of Medical Practice
  • Fibroblast Growth Factor Research
  • Advanced Materials and Mechanics
  • Nerve Injury and Rehabilitation

Institute of Materials Research and Engineering
2023-2025

Agency for Science, Technology and Research
2023-2025

Nanyang Technological University
2023-2025

University of Nottingham
2001

University College London
1994

Thermogels are a class of supramolecular hydrogels that exhibit reversible sol–gel phase transitions upon temperature changes and whose unique properties critically dependent on their constituent polymers' hydrophilic–hydrophobic balance. To date, the overwhelming majority thermogelling polymers employ poly(ethylene glycol) (PEG) as archetypical hydrophilic segment, with usage other such polyethylenimine (PEI) virtually unknown. Herein, we expand possibilities in thermogel polymer design...

10.1021/acs.macromol.3c01600 article EN Macromolecules 2023-11-22

Diabetes when left untreated can lead to various complications in the eye – at its most severe, leading vision loss. Injectable thermogels provide a minimally-invasive platform that facilitates treatment and recovery of these patients.

10.1039/d3lp00136a article EN cc-by-nc RSC Applied Polymers 2023-01-01

Injectable thermoresponsive hydrogels (thermogels), valued for their conformability and minimal invasiveness, are increasingly used as in situ forming implants drug delivery regenerative scaffolds. These gels exhibit sol-to-gel phase transitions at body temperature. As localized depots scaffolds, these determine the chemical mechanical environments could dramatically influence release kinetics of drugs or fate cells. Current synthetic approaches thermogels, however, often limit ability to...

10.1021/acsami.4c15889 article EN ACS Applied Materials & Interfaces 2024-11-19

10.1097/00006123-197907010-00014 article EN Neurosurgery 1979-07-01
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