A5104669023- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Reproductive biology and impacts on aquatic species
- Eating Disorders and Behaviors
- Selenium in Biological Systems
- Reproductive Physiology in Livestock
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Cord Injury Research
- Traumatic Brain Injury Research
- Restless Legs Syndrome Research
- Housing Market and Economics
- Material Properties and Processing
- Computational Drug Discovery Methods
- Freezing and Crystallization Processes
- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Genetic and phenotypic traits in livestock
- Nerve injury and regeneration
- Pharmacogenetics and Drug Metabolism
- Pharmacology and Obesity Treatment
- Ruminant Nutrition and Digestive Physiology
- Innovative Microfluidic and Catalytic Techniques Innovation
Anhui Agricultural University
2023-2024
Lam Research (United States)
2012
South China University of Technology
2009
Cytochrome P450 (CYP) is one of the most important drug-metabolizing enzyme families, which participates in biotransformation many endogenous and exogenous compounds. Quantitative analysis CYP expression levels when studying efficacy new drug molecules assessing drug-drug interactions development. At present, chemical probe-based assay widely used approach for evaluation activity although there are cross-reactions between isoforms with high sequence homologies. Therefore, quantification each...
Traumatic spinal cord injury (SCI) causes marked neuropathological changes in the cord, resulting limited functional recovery. Currently, there are no effective treatments, and mechanisms underlying these not completely understood. In this study, two-dimensional gel electrophoresis coupled with mass spectrometry was used to investigate injury-related abundance (SYPRO Ruby stain) phosphorylation (Pro-Q Diamond of proteins from soluble fraction lesion epicenter at 24 h following SCI. Over 1500...
Abstract To investigate the effect of Y-27632 on low-temperature metabolism sheep sperm, different concentrations were added to semen at 4 °C in this experiment detect indicators such as sperm motility, plasma membrane, acrosome, antioxidant performance, mitochondrial membrane potential (MMP), and metabolomics. The results showed that addition 20 µM significantly increased integrity rate, acrosome capacity, MMP level, adenosine triphosphate (ATP) total cholesterol content, reduced Ca2+...
Y-27632, as a cytoskeleton protector, is commonly used for low-temperature preservation of cells. Goat sperm are prone to damage the under conditions, leading loss vitality. However, Y-27632 small molecule has not yet been in research on goat semen. This study aims address issue low temperature-induced motility goats by using and explore regulation metabolism. At temperature 4 °C, different concentrations were added diluent. The quality temperature-preserved semen was evaluated detecting...
Objective: The purpose of this study was to explore the effect sodium salicylate (SS) on semen preservation and metabolic regulation in goats.Methods: Under condition low temperature, SS added goat diluent detect sperm motility, plasma membrane, acrosome, antioxidant capacity, mitochondrial membrane potential (MMP) metabonomics.Results: results show that at 8th day low-temperature storage, motility 20 μM group 66.64%, integrity rates acrosome were both above 60%, significantly higher than...
Probiotics have been proven to improve the growth performance of livestock and poultry. The aim this experiment was investigate effects probiotic supplementation on performance; rumen intestinal microbiota; fluid, serum, urine metabolism; epithelial cell transcriptomics fattening meat sheep. Twelve Hu sheep were selected randomly divided into two groups. They fed a basal diet (CON) or supplemented with 1.5 × 108 CFU/g probiotics (PRB). results show that average daily weight gain, volatile...
The aim of this study was to investigate the effects sodium salicylate (SS) on preservation and metabolic regulation sheep sperm. Under 4 °C low-temperature conditions, SS (at 10 µM, 20 30 50 µM) added semen diluent detect sperm motility, plasma membrane, acrosome integrity. Based selected optimal concentration (20 µM), µM sperms’ antioxidant capacity mitochondrial membrane potential (MMP) were evaluated, metabolomics analysis conducted. results showed that 20th day storage, motility group...