B. N. Liu

ORCID: 0009-0005-9305-6787
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About
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Research Areas
  • Analytical Chemistry and Chromatography
  • Natural product bioactivities and synthesis
  • Ubiquitin and proteasome pathways
  • Synthesis and Reactions of Organic Compounds
  • Advanced Chemical Sensor Technologies
  • Fatty Acid Research and Health
  • Magnetic confinement fusion research
  • Superconducting Materials and Applications
  • Eicosanoids and Hypertension Pharmacology
  • Neurogenesis and neuroplasticity mechanisms
  • Pesticide Residue Analysis and Safety
  • Phytochemicals and Antioxidant Activities
  • Food Quality and Safety Studies
  • Biopolymer Synthesis and Applications
  • Histone Deacetylase Inhibitors Research
  • Safety and Risk Management
  • Fusion materials and technologies
  • Structural and Chemical Analysis of Organic and Inorganic Compounds
  • Protein Degradation and Inhibitors
  • Biochemical effects in animals
  • Plant biochemistry and biosynthesis
  • PARP inhibition in cancer therapy
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cancer-related gene regulation
  • Essential Oils and Antimicrobial Activity

Shanghai Institute of Materia Medica
1988-2025

University of Chinese Academy of Sciences
2025

Chinese Academy of Sciences
1988-2024

Southern Medical University
2024

Nanchang University
2024

Institute of Plasma Physics
2023

University of Science and Technology of China
2023

Long-chain unsaturated fatty acids (UFA) can easily be converted on a microgram scale to the corresponding 2-alkenyl-4,4-dimethyloxazolines by condensation with 2-amino-2-methylpropanol (AMP). These modified molecules 'hidden' carboxyl group have been proved class of useful derivatives for gas chromatography/mass spectrometry (GC/MS) UFA mixtures. While possessing very good GC characteristics, title compounds show regular, well-recognizable diagnostic ion peaks double bond position in chain....

10.1002/bms.1200150106 article EN Biomedical & environmental mass spectrometry 1988-01-01

Abstract 2‐Substituted 4,4‐dimethyloxazolines (DMOX) have been found to be a useful alternative the commonly used methyl esters for localization of unsaturated bounds and other substituents in fatty chain by mass spectrometry. The powerful directed fragmentation coupled with good gas chromatographic ability enables structure elucidation modified acids complex mixtures. Continuing our previous study, 76 out total 86 obtained from preen gland wax shanghai duck now identified...

10.1007/bf02536225 article EN Lipids 1988-08-01

Abstract A new approach to the derivatization and analysis of long chain polyunsaturated fatty acids is described. The method based on formation 2‐alkenyl‐4,4‐dimethyloxazolines by condensation starting material with 2‐amino‐2‐methylpropanol. rapid, efficient specific respect feature parent acids. Volatility, comparable that corresponding simple esters, improved gas chromatographic separation are achieved without difficulty. derivatives exhibit clear regular fragmentation patterns allow easy...

10.1007/bf02535269 article EN Lipids 1989-01-01

Abstract Location of triple bond in long‐chain fatty acids has been effected by mass spectrometry or gas chromatography‐mass their 4,4‐dimethyloxazoline (DMOX) derivatives. The position acetylenic linkage, either isolated conjugated with olefinic bond(s) is indicated a clear separation 10 atomic units between the highest peaks two neighboring fragment clusters. acid components kernel oil Pyrularia edulis were found to be 17:1(8a), 18:1(9a), 18:2(9a,11), 18:2(9a,17) and 18:3(9a,11,17).

10.1007/bf02546071 article EN Journal of the American Oil Chemists Society 1989-02-01

Abstract The structures of cyclopentenyl fatty acids in the seed oils Hydnocarpus anthelmintica Pierre et Laness., H. alphina Wight, hainanensis (Merr.) and Taraktogenos merrilliana C.Y. Wu, all belonging to family Flacourtiaceae, have been identified by GC‐MS mixed 2‐substituted 4,4‐dimethyloxazoline (DMOX) derivatives. These variations are characterized presence key fragments at (M‐43), (M‐55) (M‐67), while location a double bond chain is indicated 12‐mass interval between highest peaks...

10.1007/bf02546068 article EN Journal of the American Oil Chemists Society 1989-02-01

Adult hippocampal neurogenesis (AHN) is crucial to various brain functions. Neurodegeneration, neuroinflammation and stress can impair AHN, contributing the development of neurological psychiatric disorders. Stress known extensively affect both peripheral immune system. However, cellular molecular mechanisms underlying stress-induced impairments in AHN remain unclear. In this study, we found that, unlike neuroinflammatory conditions, significantly inhibited independently microglial...

10.14336/ad.2024.0835 article EN cc-by Aging and Disease 2024-01-01

Vertical instability (VI) is one of the main challenges for fusion energy realization through advanced tokamak. The disruption caused by VI known as vertical displacement event (VDE). VDE not only causes serious thermal load to plasma-facing components but also generates huge mechanical first wall. growth rate a crucial parameter identification active control displacement. In this work, multilayer perceptron (MLP) model employed estimate plasma ( <inline-formula...

10.1109/tps.2023.3321377 article EN IEEE Transactions on Plasma Science 2023-10-01
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