A5082374395- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Cancer Genomics and Diagnostics
- Reproductive tract infections research
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Epigenetics and DNA Methylation
- Molecular Biology Techniques and Applications
- Genetic Associations and Epidemiology
- Colorectal Cancer Treatments and Studies
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Glioma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
Chinese University of Hong Kong
2018-2024
University of Hong Kong
2023-2024
Norwegian Womens Public Health Association
2020
Abstract BACKGROUND A recent study has reported that the microbiota in endometrial fluid of patients receiving vitro fertilization and embryo transfer (IVF-ET) may predict implantation pregnancy rates. However, studies are lacking simultaneously compare between tissue samples. Whether composition reflects remains unclear. METHODS We systematically profiled samples IVF-ET using massively parallel sequencing. The bacterial 16S ribosomal RNA gene (V4 region) was PCR-amplified. Sequencing reads...
The genetic bases of many common diseases have been identified through genome-wide association studies in the past decade. However, application this approach on public healthcare planning has not well established. Using Macau with population around 650,000 as a basis, we conducted pilot study to evaluate feasibility genomic research and its potential health decisions. By performing SNP genotyping over thousand individuals, evaluated risk profiles 47 non-communicable traits, two traits...
(Abstracted from Fertil Steril 2019;112:707–717) Chronic endometriosis (CE), a state of chronic inflammation in the endometrial lining, has been associated with reproductive failure and is diagnosed based on presence CD138+ plasma cells. There wide variance CE among infertile women (ranging 2.8% to 57%) lack consensus diagnostic criteria.
e15174 Background: Large population-based comprehensive tumor genomic profiling using next-generation sequencing (NGS) technology offers insight into the detection of copy number variation (CNV) in advanced/metastatic solid cancers. However, significance and role CNV advanced-stage non-small cell lung cancer (NSCLC) is limited. In this analysis, we investigated incidence impact on patient outcomes. Methods: Patients were recruited as part an ongoing real-world multicentre prospective NSCLC...
8019 Background: Recent studies on the perioperative treatment of Non-Small Cell Lung Cancer (NSCLC) have often excluded patients with stage IA. To address this issue and bridge knowledge gap, we aim to investigate impact PD-L1 EGFR status survival in IA NSCLC. Methods: Our study aimed determine expression overall (OS) resectable IA-IIIB NSCLC who underwent curative resection between May 2010 April 2020. We analyzed clinicopathological data categorized based tumor proportion score (TPS). TPS...
Abstract BACKGROUND Glioblastoma (GB), the most aggressive form of brain tumor, presents a significant clinical challenge with devastating prognosis. Globally, median overall survival (OS) for GB is typically 12-15 months, largely due to its inherent resistance chemotherapy and radiotherapy. However, some patients exhibit prolonged survival, their specific demographic genomic characteristics remain poorly defined. Understanding profile these exceptional responders holds great promise...