A5009721225- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Pregnancy and preeclampsia studies
- Reproductive Biology and Fertility
- Ectopic Pregnancy Diagnosis and Management
- Gynecological conditions and treatments
- Prenatal Screening and Diagnostics
- Neuroinflammation and Neurodegeneration Mechanisms
- Single-cell and spatial transcriptomics
- Uterine Myomas and Treatments
- Pregnancy and Medication Impact
- Endometrial and Cervical Cancer Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Reproductive Physiology in Livestock
- Nutritional Studies and Diet
- Computational Drug Discovery Methods
- Reproductive tract infections research
- Autism Spectrum Disorder Research
- Medicinal Plant Pharmacodynamics Research
- Cell Adhesion Molecules Research
- Pressure Ulcer Prevention and Management
- Climate Change and Health Impacts
- Pain Mechanisms and Treatments
- Molecular Biology Techniques and Applications
Maternal and Child Health Care Hospital of Bao'an
2025
Jinan University
2022-2025
Chinese University of Hong Kong
2015-2025
Chinese Academy of Sciences
2024-2025
Chengdu University of Traditional Chinese Medicine
2025
Dalian National Laboratory for Clean Energy
2025
Dalian Institute of Chemical Physics
2025
Chinese University of Hong Kong, Shenzhen
2025
Shenzhen Institutes of Advanced Technology
2025
Krembil Research Institute
2022-2024
Metformin, a widely used hypoglycemic drug, reduces stroke incidence and alleviates chronic inflammation in clinical trials. However, the effect of metformin ischemic is unclear. Here, we investigated on mice further explored possible underlying mechanisms.Ninety-eight adult male CD-1 underwent 90-minute transient middle cerebral artery occlusion (tMCAO). Metformin (200 mg/kg) was administrated for up to 14 days. Neurobehavioral outcomes, brain infarct volume, inflammatory factors,...
Accumulating evidence indicates a significant increase in CD56 + endometrial NK cells women with reproductive failure. However, alone inadequately captures the phenotypic and functional heterogeneity of these cells. This study aims to compare density various subsets between failure healthy controls, as well evaluate their diagnostic performance. included three groups: recurrent miscarriage (RM), repeated implantation (RIF), 56 each group. Endometrial biopsy was performed precisely 7 days...
The endometrium becomes receptive to the embryo only in mid-luteal phase, but not other stages of menstrual cycle. Endometrial factors play an important role implantation. Women with recurrent miscarriage and implantation failure have both been reported altered expression receptivity markers during window We aimed compare gene profiles among women unexplained failures (RIF) miscarriages (RM) by RNA sequencing (RNA-Seq). In total 20 patients (9 RIF 11 RM) were recruited. addition 4 fertile...
The brain is spatially organized and contains unique cell types, each performing diverse functions exhibiting differential susceptibility to neurodegeneration. This exemplified in Parkinson's disease with the preferential loss of dopaminergic neurons substantia nigra pars compacta. Using a transgenic model, we conducted single-cell spatial transcriptomic neuron translatomic analysis young old mouse brains. Through high resolving capacity transcriptomics, provide deep characterization...
Abstract BACKGROUND A recent study has reported that the microbiota in endometrial fluid of patients receiving vitro fertilization and embryo transfer (IVF-ET) may predict implantation pregnancy rates. However, studies are lacking simultaneously compare between tissue samples. Whether composition reflects remains unclear. METHODS We systematically profiled samples IVF-ET using massively parallel sequencing. The bacterial 16S ribosomal RNA gene (V4 region) was PCR-amplified. Sequencing reads...
Abstract Despite increasing preventive efforts, pressure injury still occurs in intensive care patients. This study was aimed to describe prevalence, risk factors, and prevention practices adult a multi‐centre, one‐day, prospective point prevalence which total of 198 units from 21 provinces China participated. Overall ICU‐acquired patients were 12.26% 4.31%, respectively. Consistent with earlier reports, almost half the injuries at stage I, one‐fourth 2, most common body sites for sacral...
Importance China carries a heavy burden of postherpetic neuralgia, with an unmet need for novel drugs greater efficacy and less prominent neurotoxic effects than existing calcium channel ligands. Objective To investigate the safety crisugabalin, oral α2δ-1 subunit ligand, neuralgia. Design, Setting, Participants This randomized clinical trial, carried out between November 9, 2021, January 5, 2023, at 48 tertiary care centers across had 2 parts. Part 1 was phase 3, multicenter, randomized,...
Vitamin D deficiency is associated with numerous public health issues. Limited data are available for children in southern China, a region that receives abundant sunlight. We aimed to estimate the 25-hydroxyvitamin (25(OH)D) levels area, and determine seasonal variations serum 25(OH)D levels. A total of 16,755 aged 0 6 years, who visited Guangdong Women Children's Hospital examination between January 2016 May 2017, were included present study. The ranged from 10.5 307.4 nmol/L (mean ±...
Social isolation (ISO) is associated with an increased risk and poor outcomes of ischemic stroke. However, the roles mechanisms ISO in stroke-associated pneumonia (SAP) remain unclear. Adult male mice were single- or pair-housed ovariectomized female mouse then subjected to transient middle cerebral artery occlusion. Isolated treated natriuretic peptide receptor A antagonist A71915 anti-gamma-delta (γδ) TCR monoclonal antibody, whereas recombinant human atrial (rhANP). Subdiaphragmatic...