A5000229835- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Genomics and Phylogenetic Studies
- Adipose Tissue and Metabolism
- Heavy Metal Exposure and Toxicity
- Erythropoietin and Anemia Treatment
- Erythrocyte Function and Pathophysiology
- Genetic diversity and population structure
- Robot Manipulation and Learning
- Mechanisms of cancer metastasis
- RNA and protein synthesis mechanisms
- Machine Learning in Bioinformatics
- Cancer Cells and Metastasis
- Insect Resistance and Genetics
- Manufacturing Process and Optimization
- Plant and Fungal Interactions Research
- Plant Taxonomy and Phylogenetics
- Flexible and Reconfigurable Manufacturing Systems
- Cancer Research and Treatments
Czech Technical University in Prague
2023
Czech Academy of Sciences, Institute of Physiology
2011
Swiss Integrative Center for Human Health
2011
University Medical Center Freiburg
2011
University of Zurich
2011
Genomics (United Kingdom)
2011
Harvard University Press
2005
Harvard University
2000-2002
Fukushima Medical University
2000
Brigham and Women's Hospital
2000
We have sequenced the genome of a second Drosophila species, pseudoobscura , and compared this to sequence melanogaster primary model organism. Throughout evolution vast majority genes remained on same chromosome arm, but within each arm gene order has been extensively reshuffled, leading minimum 921 syntenic blocks shared between species. A repetitive is found in D. at many junctions adjacent blocks. Analysis novel element family suggests that recombination offset elements may given rise...
Abstract Rampant activity of the hypoxia-inducible factor (HIF)-1 in cancer is frequently associated with malignant progression into a harder-to-treat, increasingly aggressive phenotype. Clearly, anti-HIF strategies cells are considerable clinical interest. One way to fine-tune, or inhibit, HIF's transcriptional outflow independently hydroxylase activities could be through competing transcription factors. A CACGTG-binding human hepatoma was previously found restrict access hypoxia response...
Robotic cells in industrial automation use different programming and description languages, which are typically almost hard-wired the program solutions do not allow a goal product to be changed easily. Using unification language allows focusing on solution itself. An independent of capabilities intentions offers way for changing also distributing process locations. Moreover, based description, knowledge model can created check if exists defined resource capabilities. If is implemented...
<div>Abstract<p>Rampant activity of the hypoxia-inducible factor (HIF)-1 in cancer is frequently associated with malignant progression into a harder-to-treat, increasingly aggressive phenotype. Clearly, anti-HIF strategies cells are considerable clinical interest. One way to fine-tune, or inhibit, HIF's transcriptional outflow independently hydroxylase activities could be through competing transcription factors. A CACGTG-binding human hepatoma was previously found restrict access...
<div>Abstract<p>Rampant activity of the hypoxia-inducible factor (HIF)-1 in cancer is frequently associated with malignant progression into a harder-to-treat, increasingly aggressive phenotype. Clearly, anti-HIF strategies cells are considerable clinical interest. One way to fine-tune, or inhibit, HIF's transcriptional outflow independently hydroxylase activities could be through competing transcription factors. A CACGTG-binding human hepatoma was previously found restrict access...