Lan Liang

ORCID: 0009-0006-1004-5714
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About
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Research Areas
  • Healthcare Policy and Management
  • Smoking Behavior and Cessation
  • Obesity, Physical Activity, Diet
  • Health disparities and outcomes
  • Obesity and Health Practices
  • Global Health Workforce Issues
  • Primary Care and Health Outcomes
  • Global Health Care Issues
  • Cancer-related molecular mechanisms research
  • Medical Malpractice and Liability Issues
  • Food Security and Health in Diverse Populations
  • Emergency and Acute Care Studies
  • Healthcare cost, quality, practices
  • Consumer Market Behavior and Pricing
  • Cancer therapeutics and mechanisms
  • Economics of Agriculture and Food Markets
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Drug Transport and Resistance Mechanisms
  • Legal Education and Practice Innovations
  • Regulation and Compliance Studies
  • Respiratory viral infections research
  • Occupational and Professional Licensing Regulation
  • Influenza Virus Research Studies
  • Reading and Literacy Development
  • Lung Cancer Treatments and Mutations

Henan Normal University
2020-2025

Agency for Healthcare Research and Quality
2008-2024

Shaanxi University of Chinese Medicine
2022-2024

Shaanxi Polytechnic Institute
2024

The People's Hospital of Guangxi Zhuang Autonomous Region
2018-2023

Army Medical University
2019-2022

The Affiliated Yongchuan Hospital of Chongqing Medical University
2022

Chongqing Medical University
2022

Southwest Hospital
2019-2021

University of Electronic Science and Technology of China
2020

We projected future prevalence and BMI distribution based on national survey data (National Health Nutrition Examination Study) collected between 1970s 2004. Future obesity‐related health‐care costs for adults were estimated using prevalence, Census population projections, published estimates of per capita excess obesity/overweight. The objective was to illustrate potential burden obesity overweight in the United States that would occur if current trends continue. Overweight have increased...

10.1038/oby.2008.351 article EN Obesity 2008-08-19

Coronavirus disease 2019 (COVID-19) has spread worldwide. To date, no specific drug for COVID-19 been developed. Thus, this randomized, open-label, controlled clinical trial (ChiCTR2000029853) was performed in China. A total of 20 mild and common patients were enrolled randomly assigned to receive azvudine symptomatic treatment (FNC group), or standard antiviral (control group). The mean times the first nucleic acid negative conversion (NANC) ten FNC group control are 2.60 (SD 0.97; range...

10.1002/advs.202001435 article EN cc-by Advanced Science 2020-07-14

We explored the association between community racial/ethnic composition and obesity risk.

10.2105/ajph.2011.300452 article EN American Journal of Public Health 2012-06-14

Ionic aluminum (Al) in acidic soils, comprising approximately 50% of arable land globally, is highly toxic to most plant species. Populus grow naturally soils and tolerate high concentrations Al. Multidrug compound extrusion (MATE) family genes plants are involved responses Al tolerance. To date, however, the functional roles MATE remain unclear. In present study, 71 putative transporters were predicted genome trichocarpa. The chromosome distribution, phylogenetic relationships, expression...

10.1093/jxb/erx370 article EN cc-by Journal of Experimental Botany 2017-09-01

In preclinical and phase I II clinical studies, 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) displays a potent long-lasting inhibition of HIV-1 infection. To investigate its mechanism action, we compared it with the well-documented lamivudine (3TC). Pharmacokinetic studies revealed that intracellular retention FNC triphosphate in peripheral blood mononuclear cells was markedly longer than 3TC triphosphate. selectively enters is retained HIV target cells, where exerts prevention addition to...

10.1021/acs.jmedchem.0c00940 article EN Journal of Medicinal Chemistry 2020-07-17

Experts have recommended the adoption of health literacy universal precautions, whereby care providers make all information easier to understand, confirm everyone's comprehension, and reduce difficulty health-related tasks. The U.S. Department Health Human Services selected three literate practices track progress in precautions.

10.3928/24748307-20170929-01 article EN cc-by-nc HLRP Health Literacy Research and Practice 2017-10-01

Few studies have examined parent-child resemblance in body weight status using nationally representative data for the US.We analyzed Body Mass Index (BMI), status, and related correlates 4,846 boys, 4,725 girls, their parents based on US from 2006 2007 Medical Expenditure Panel Survey (MEPS). Pearson partial correlation coefficients, percent agreement, weighted kappa binary multinomial logistic regression were used to examine resemblance, adjusted complex sampling design.Pearson coefficients...

10.1371/journal.pone.0065361 article EN cc-by PLoS ONE 2013-06-10

<h3>Importance</h3> Rural hospitals are increasingly merging with other hospitals. The associations of hospital mergers quality care need further investigation. <h3>Objectives</h3> To examine changes in for patients at rural that merged compared those remained independent. <h3>Design, Setting, and Participants</h3> In this case-control study, community nonrehabilitation Federal Office Health Policy–eligible zip codes during 2009 to 2016 32 states were identified from Irving Levin Associates...

10.1001/jamanetworkopen.2021.24662 article EN cc-by-nc-nd JAMA Network Open 2021-09-20

A novel 2′-α-fluoro-2′-β-C-(fluoromethyl) purine nucleoside phosphoramidate prodrug 15 has been designed and synthesized to treat SARS-CoV-2 infection. The central replication transcription complex (C-RTC, nsp12-nsp7-nsp82) catalyzed in vitro RNA synthesis was effectively inhibited by the corresponding bioactive triphosphate (13-TP). cryo-electron microscopy structure of C-RTC:13-TP also determined. Compound exhibited potent antiviral activity against 20SF107 strain (EC50 = 0.56 ± 0.06 μM)...

10.1021/acs.jmedchem.4c02769 article EN Journal of Medicinal Chemistry 2025-01-13

Objectives: Data from the 1992, 1993, and 1994 Monitoring Future Surveys were used to investigate differential effects of cigarette price on intensity youth smoking Methods: Respondents classified into non-smokers; individuals who smoked less than one per day; five cigarettes one-half pack a or more day. A Threshold Change Model was estimated with information prices as main explanatory variables. Results: Dummy variables indicating medium high found have varying different levels intensity,...

10.1080/14622200110103188 article EN Nicotine & Tobacco Research 2002-02-01

This study describes the dimensionality and continuum of Spanish phonological awareness (PA) skills in 3- to 6-year-old children. A 3 × 4 factorial design crossed word structure test items (word, syllable, phoneme) with task (blending multiple-choice, blending free-response, elision free-response) assess 12 PA skills. Over 1,200 speakers were assessed at 2 points time. Confirmatory factor analyses found that a 2nd-order unifying ability along 1st-order factors well explained children's...

10.1037/a0025024 article EN Journal of Educational Psychology 2011-08-22

Importance COVID-19 pandemic-related disruptions to the health care system may have resulted in increased mortality for patients with time-sensitive conditions. Objective To examine whether in-hospital hospitalizations not related (non–COVID-19 stays) conditions changed during pandemic and how it varied by hospital urban vs rural location. Design, Setting, Participants This cohort study was an interrupted time-series analysis assess (March 8, 2020, December 31, 2021) compared prepandemic...

10.1001/jamanetworkopen.2024.1838 article EN cc-by-nc-nd JAMA Network Open 2024-03-12

Examine the rate of screening for adolescent overweight and obesity by pediatric health care professionals provision advice on healthy eating physical activity.Our sample contains adolescents 11 to 17 years old (6911 girls 6970 boys) from 2001-2007 Medical Expenditure Panel Survey who reported having at least 1 provider visit in previous 12 months. Using logistic regression, we investigated factors associated with whether parents that their children were weighed measured they or received...

10.1542/peds.2011-0596 article EN PEDIATRICS 2012-06-05

// Yan-Rong Liu 1, * , Lan Liang 3, Jian Min Zhao 4, Yang Zhang 5, 2 Wei-Long Zhong Qiang Jun-Jie Wei Meng Li Jie Yuan Shuang Chen 1 Shu-Min Zong Hui-Juan Jing Qin Bo Sun Hong-Gang Zhou Tao and Cheng Tianjin Key Laboratory of Molecular Drug Research, International Joint Academy Biomedicine, Tianjin, China State Medicinal Chemical Biology College Pharmacy, Nankai University, 3 GoalGen Biotechnology Co., Ltd., 4 Pathology Department, Shun Yi District Hospital, Beijing, 5 Department...

10.18632/oncotarget.17548 article EN Oncotarget 2017-05-02

Despite rural hospitals' central role in their communities, they are increasingly financial distress and may merge with other hospitals or health systems, potentially reducing service lines that less profitable duplicative of services the acquirer also offers. Using hospital discharge data from thirty-two Healthcare Cost Utilization Project State Inpatient Databases period 2007–18, we examined influence mergers on changes to inpatient at within catchment areas. We found merged were more...

10.1377/hlthaff.2021.00160 article EN Health Affairs 2021-10-01

Abstract Zero tolerance laws make it illegal per se for anyone under age 21 to drive with any measurable amount of blood alcohol. Although a link has been established between zero and lower motor vehicle fatalities, research not produced strong evidence on how influence individual alcohol use drinking driving behaviors. Using unique data set difference‐in‐difference‐in‐difference‐type design, we are able analyze number pathways through which can work among an important underage population,...

10.1002/hec.1321 article EN Health Economics 2008-01-25

ABSTRACT Aims Little is known about smoking during the transition to college. The current study examined trajectories of among college freshmen, how predicted later and social context smoking. Design Weekly assessments daily were collected via web first year for a large cohort with previous history Participants setting A total 193 freshmen from public university who smoked frequently enough be included in trajectory analysis. Measurements Measures weekly reports smoking, family perceived...

10.1111/j.1360-0443.2008.02280.x article EN Addiction 2008-08-07

Fluctuations in patient volume during the COVID-19 pandemic may have been particularly concerning for rural hospitals. We examined hospital discharge data from Healthcare Cost and Utilization Project State Inpatient Databases to compare period (March 8, 2020–December 31, 2021) with prepandemic (January 1, 2017–March 7, 2020). Changes average daily medical at hospitals showed a dose-response relationship community burden, ranging 13.2 percent decrease periods of low transmission 16.5 increase...

10.1377/hlthaff.2023.00678 article EN Health Affairs 2024-05-01

<h3>Importance</h3> The increase in rural hospital closures has strained access to inpatient care communities. It is important understand the association between system affiliation and these communities inform policy on this issue. <h3>Objective</h3> To examine closure. <h3>Design, Setting, Participants</h3> This cohort study used survival models with a time-dependent variable for vs independent status assess risk of closure among national US hospitals from January 2007 through December...

10.1001/jamahealthforum.2022.1835 article EN cc-by-nc-nd JAMA Health Forum 2022-07-01

Although many studies have recently investigated how the product quality impacts on economic and environment performance under remanufacturing, all of them assume that remanufacturing operations are undertaken by original equipment manufacturers (OEMs) or independent remanufacturers (IRs). However, OEMs such as Lexmark, Canon, Epson filed lawsuits with those IRs without licensing, but outsourced to several contracted (CRs). We therefore extend prior research investigate environmental...

10.3390/su12030874 article EN Sustainability 2020-01-24
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