Yiyun Chiang

ORCID: 0009-0006-1781-2824
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About
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Research Areas
  • Nutrition and Health in Aging
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • SARS-CoV-2 and COVID-19 Research
  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • COVID-19 Clinical Research Studies
  • Colorectal Cancer Screening and Detection
  • Metabolomics and Mass Spectrometry Studies
  • Global Cancer Incidence and Screening
  • Economic and Financial Impacts of Cancer
  • HIV-related health complications and treatments
  • Cardiovascular Health and Risk Factors
  • Retinal and Optic Conditions
  • Metabolism and Genetic Disorders

Emory University
2021-2024

Acumen (United States)
2023-2024

Roche (China)
2021

Importance In January 2023, the US Centers for Disease Control and Prevention Food Drug Administration noted a safety concern ischemic stroke among adults aged 65 years or older who received Pfizer-BioNTech BNT162b2; WT/OMI BA.4/BA.5 COVID-19 bivalent vaccine. Objective To evaluate risk after administration of (1) either brand vaccine, (2) plus high-dose adjuvanted influenza vaccine on same day (concomitant administration), (3) Design, Setting, Participants Self-controlled case series...

10.1001/jama.2024.1059 article EN JAMA 2024-03-19

Genome-wide association studies (GWAS) of circulating metabolites have revealed the role genetic regulation on human metabolome. Most previous investigations focused European ancestry, and few been conducted among populations African descent living in Africa, where infectious disease burden is high (e.g., immunodeficiency virus (HIV)). It important to understand associations metabolome diverse at-risk including people with HIV (PWH) Africa. After a thorough literature review, reported...

10.3390/metabo12070624 article EN cc-by Metabolites 2022-07-06

ABSTRACT In January 2023, the United States Food and Drug Administration Centers for Disease Control Prevention noted a safety concern ischemic stroke in adults ≥65 years receiving BNT162b2; WT/OMI BA.4/BA.5 COVID-19 bivalent vaccine. This self-controlled case series analysis evaluated risk among Medicare fee-for-service beneficiaries aged receiving: 1) Pfizer-BioNTech (BNT162b2; BA.4/BA.5) or Moderna (mRNA-1273.222) vaccine, 2) high-dose/adjuvanted influenza vaccines, 3) concomitant...

10.1101/2023.10.10.23296624 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2023-10-15

Background Heart failure (HF) is a serious condition with increasing prevalence, high morbidity, and increased mortality. Obesity an established risk factor for HF. Fluctuation in body mass index (BMI) has shown higher of cardiovascular outcomes. We investigated the association between BMI variability incident Methods Results In UK Biobank, we prospective cohort after excluding participants prevalent HF or cancer at enrollment. A total 99 368 White ≥3 measures during >2 years preceding...

10.1161/jaha.123.031861 article EN cc-by-nc-nd Journal of the American Heart Association 2024-04-30

Introduction: Heart failure (HF) is a disease with high morbidity and mortality, affects an estimated total of 6.2 million HF patients in the US. Obesity established risk factor for HF, fluctuation body mass index (BMI) has shown negative effect health. Hypothesis: We assessed hypothesis that BMI variability associated incident HF. Methods: This study used data from UK Biobank, which prospective cohort median follow-up 12.5 years. After excluding prevalent or cancer at enrollment, 99,368...

10.1161/circ.147.suppl_1.p581 article EN Circulation 2023-02-28

Abstract Background Heart failure (HF) is a serious condition with increasing prevalence, high morbidity, and increased mortality. Obesity an established risk factor for cardiovascular diseases, including HF. Fluctuation in body mass index (BMI) has shown higher of outcomes. We investigated the association between BMI variability incident Methods In UK Biobank, we prospective cohort after excluding participants prevalent HF or cancer at enrollment. A total 99,368 White (British, Irish, any...

10.1101/2023.03.30.23287990 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2023-03-31
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