A5076644180- Occupational and environmental lung diseases
- Pleural and Pulmonary Diseases
- Medical Imaging and Pathology Studies
- Cancer Research and Treatments
- Cancer Immunotherapy and Biomarkers
- Bee Products Chemical Analysis
- Metalloenzymes and iron-sulfur proteins
- Advanced battery technologies research
- Biochemical effects in animals
- Coenzyme Q10 studies and effects
- Electrocatalysts for Energy Conversion
- Innovation and Knowledge Management
Harbin Institute of Technology
2010-2024
Swiss Cancer Center Léman
2024
École Polytechnique Fédérale de Lausanne
2024
University of Lausanne
2024
<div>Abstract<p>Pleural mesothelioma is a fatal disease with limited treatment options. Recently, pleural management has improved the development of immune checkpoint inhibitors (ICI). In first-line therapy, dual PD-1 and CTLA-4 blockade enhances tumor control patient survival compared chemotherapy. Unfortunately, only fraction patients responsive to immunotherapy, approaches reshape microenvironment make ICIs more effective are urgently required. this study, we evaluated effect...
<p>Supplementary Figure S5: Impact of HITOC on tumor-infiltrating T cells.</p>
<p>Supplementary Figure S3: Representative flow cytometry histograms.</p>
<p>Supplementary Figure S4: Effect of HITOC on CD4 T cell infiltration in tumors.</p>
<p>Supplementary Figure S1: Evaluation of the impact heat adjunct on cisplatin cytotoxicity.</p>
<p>Supplementary Figure S6: Effect of HITOC on PD-1 and CTLA-4 expression by CD4 T cells.</p>
<p>Supplementary Figure S2: Flow cytometry gating.</p>
Abstract Pleural mesothelioma is a fatal disease with limited treatment options. Recently, pleural management has improved the development of immune checkpoint inhibitors (ICI). In first-line therapy, dual PD-1 and CTLA-4 blockade enhances tumor control patient survival compared chemotherapy. Unfortunately, only fraction patients responsive to immunotherapy, approaches reshape microenvironment make ICIs more effective are urgently required. this study, we evaluated effect hyperthermic...
Abstract Neurodegenerative disorders are chronic, progressive neurological diseases characterized by damage to neuron cells. Oxidative stress and neuroinflammation play crucial roles in inducing these disorders. Caffeic acid phenethyl ester (CAPE) its sulfone derivatives have demonstrated antioxidant anti‐inflammatory effects, suggesting their potential as neuroprotective agents. In this study, 8 were designed synthesized explore the importance of catechol structure–activity relationship...
Hydrogen has the potential to serve as a new energy resource, reducing greenhouse gas emissions that contribute climate change. Natural hydrogenases exhibit impressive catalytic abilities for hydrogen production, but they often lack oxygen tolerance. Oxygen-tolerant can work under by reacting with form inactive states, which be reactivated states atom removal. Herein, we synthesized three NiFeSe complexes: (NiSe(CH3)FeCp, NiSe(CH3)FeCp* and NiSe(PhNMe2)FeCp) features of active sites...
Globalization leads to the movement of companies towards international cooperation in manufacturing. Manufacturing strategy (MS) is one most important issues for manufacturing secure sustainable advantage. It imperative understand their cooperators ensure success. In last decades, more and Sino-German cooperative has been occurred. China differs from Germany a number aspects such as economy, institution social culture. Based on an empirical study, this paper compares strategies relation...