A5061204883- HIV/AIDS drug development and treatment
- Click Chemistry and Applications
- DNA and Nucleic Acid Chemistry
- Chemical synthesis and alkaloids
- 14-3-3 protein interactions
- Sulfur Compounds in Biology
- Cholinesterase and Neurodegenerative Diseases
- Eicosanoids and Hypertension Pharmacology
- Adenosine and Purinergic Signaling
University of Pisa
2024
University of Cagliari
2021
Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari
2021
Current therapeutic protocols for the treatment of HIV infection consist combination diverse anti-retroviral drugs in order to reduce selection resistant mutants and allow use lower doses each single agent toxicity. However, avoiding interactions patient compliance are issues not fully accomplished so far. Pursuing on our investigation potential anti multi-target agents we have designed synthesized a small library biphenylhydrazo 4-arylthiazoles derivatives evaluated investigate ability new...
Current therapeutic protocols for the treatment of HIV infection consist combination diverse anti-retroviral drugs in order to reduce selection resistant mutants and allow use lower doses each single agent toxicity. However, avoiding interactions patient compliance are issues not fully accomplished so far. In this respect identification agents with multitarget potential might represent ideal solution. Accordingly, a small library biphenylhydrazo 4-arylthiazoles derivatives has been...