A5004787370- Epigenetics and DNA Methylation
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Cancer-related gene regulation
- Folate and B Vitamins Research
- Medical Image Segmentation Techniques
- Retinal Imaging and Analysis
- Gestational Diabetes Research and Management
- Corneal Surgery and Treatments
- Advanced SAR Imaging Techniques
- Cannabis and Cannabinoid Research
- Gastric Cancer Management and Outcomes
- Autophagy in Disease and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
- Sirtuins and Resveratrol in Medicine
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Microwave Imaging and Scattering Analysis
- Corrosion Behavior and Inhibition
- Hypothalamic control of reproductive hormones
- Cardiovascular Health and Disease Prevention
- Hormonal and reproductive studies
- Bone and Joint Diseases
- Mesenchymal stem cell research
- Botulinum Toxin and Related Neurological Disorders
China Science and Technology Publishing & Media
2022-2025
Beijing Biocytogen (China)
2023-2024
Nanjing Agricultural University
2023-2024
Howard University
2019-2024
Georgetown University
2023
Georgetown University Medical Center
2023
Beijing Anding Hospital
2014-2022
China Medical University
2018
Baylor University
2017
The First People's Hospital of Guiyang
2016
Objective: Stem cell therapy has emerged as a pioneering front in the biomedical domain, characterized by its rapid strides innovation and progress. Such advancements hold profound implications for public health. Notably, Europe, United States, Japan, China have all crafted comprehensive regulatory frameworks to expedite fruition of stem therapy. This article meticulously scrutinizes evaluates progression clinical trials across major global jurisdictions. It delineates trajectory evolution...
Abstract Culex pipiens is a major carrier of the West Nile Virus, leading cause mosquito-borne disease in continental United States. Cx. survive overwinter through diapause which an important survival strategy that under control insulin signaling and Foxo by regulating energy metabolism. Three homologous candidate genes, glycogen synthase ( glys ), atp-binding cassette transporter atp ) , low-density lipoprotein receptor chaperone ldlr are regulation transcription factor were identified . To...
Abstract Background The objective of this study was to examine and analyze differential methylation profiles in order investigate the influence hyper-methioninemia (HM) on development diabetic nephropathy (DN). Male Wistar rats, aged eight weeks weighing 250–300 g, were randomly assigned into four groups: a control group (Healthy, n = 8), streptozocin-induced rats (STZ group, HM + STZ ( Tangshen Formula (TSF) treatment (TSF 8). Blood glucose levels other metabolic indicators monitored before...
Mycobacteria possess a multi-layered cell wall that requires extensive remodelling during division. We investigated the role of an amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase, peptidoglycan enzyme implicated in demonstrated deletion MSMEG_6281 (Ami1) Mycobacterium smegmatis resulted formation cellular chains, illustrative cells were unable to complete Suprisingly, viability Δami1 mutant was maintained through atypical lateral branching, products which proceeded form viable...
Registration of retinal images taken at different times, from perspectives, or with modalities is a critical prerequisite for the diagnoses and treatments various eye diseases. This problem can be formulated as registration two sets sparse feature points extracted given images, it typically solved by first creating set putative correspondences then removing false matches well estimating spatial transformation between image pairs correspondence jointly involving an iteration process. However,...
Femoral head necrosis (FHN) is a common leg disease in broilers, resulting economic losses the poultry industry. The occurrence of FHN closely related to decrease number bone marrow mesenchymal stem cells (BMSCs) and change differentiation direction. This study aimed investigate function BMSCs development FHN. We isolated cultured from spontaneous FHN-affected broilers normal assessed ability into three lineages by multiple staining methods, found that demonstrated enhanced lipogenic...
Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious infections by multidrug-resistant Gram-positive pathogens. Its mode action considered to be multifaceted, encompassing targeting and depolarization bacterial cell membranes, alongside inhibition wall biosynthesis. To characterize daptomycin action, 15N cross-polarization at magic-angle spinning NMR measurements were performed on intact whole cells Staphylococcus aureus grown in presence sub-inhibitory...
BACKGROUND:This study aimed to investigate the role of miR-184 in proliferation and apoptosis keratinocyte (HaCaT cells). MATERIAL AND METHODS:HaCaT cells were cultured a growth medium. The was transfected with siRNA, then cell viability assayed by MTT flow cytometry, respectively. colony-forming efficacy HaCaT detected as well. mRNA expressions basic fibroblast factor (bFGF) transforming (TGF)-β1 measured RT-PCR. apoptosis-related proteins caspase-3 Bcl-x determined Western blot....
Polygonum cuspidatum</i> (PC), a widely used Chinese herbal medicine (CHM), plays an important role in treating various diseases including osteoarthritis (OA). Yet, the multicomponent and multitarget characteristics of PC make deciphering pharmacological mechanisms difficult.The purpose this study is to identify core molecular against OA.The Traditional Medicine Systems Pharmacology (TCMSP) database was search for active ingredients PC. GeneCards then screened establish relevant databases...
Understanding the dynamics of biofilm formation and its elemental composition is crucial for developing effective strategies against biofilm-associated infections. In this study, we employed scanning electron microscopy (SEM) energy-dispersive X-ray spectroscopy (EDS) to investigate morphological changes compositions Staphylococcus aureus biofilms. SEM images revealed distinct stages development, from initial aggregation mature aged EDS analysis consistently showed elevated levels sodium...
Objective: A meta-analysis was performed to evaluate the safety and efficacy of albumin-bound paclitaxel (Nab-PTX) versus solvent-based (Sb-PTX) for breast cancer. Methods: In this systematic review network meta-analysis, we searched databases including PubMed, Embase, Cochrane-Library, randomized controlled trials on Nab-PTX Sb-PTX Pathologic complete response (pCR), objective rate (ORR), adverse events (AEs) were collated analyzed using meta-package in R language. Results: total 13 studies...
Objective To provide the microanatomy for surgical operation spastic torticollis.Methods Through anatomy research of adult embalmed cadaver (8 cases,16 sides) to description layer、course、beginning and ending points muscle ramification course、distribution diameter spinal nerve dorsal rami nerve.Results Neck back muscles can be divided into four layers.The first layer are trapezius sternocleidomastoid; The second splenius capitis muscle、splenius cervicis levator scapulae muscle; third...
Abstract This study aimed to investigate the impact of hyper-methionine (HM) feeding on diabetic nephropathy (DN) pathogenesis by examining and analyzing differential methylation profiles. Eight-week-old male Wistar rats (250–300g) were randomly divided into four groups: control group (healthy, n = 8), streptozocin (STZ) induced DN (STZ group, STZ-induced fed with HM + Tangshen Formula (TSF) treatment for STZ (TSF 8). Blood glucose other metabolic indicators monitored before at four-week...
Blood blister like aneurysms is very easy to rupture, especially during and after surgery. Once found, it should be treated promptly. Treatment includes direct clipping, suture artery reconstruction, aneurysm wrapping, internal carotid occlusion endovascular treatment. In this article, we investigate the characteristics, clinical outcome treatment strategy of blood supraclinoid artery. Key words: Blood aneurysms; Supraclinoid; Review