Yan Zhao

ORCID: 0009-0006-3453-4897
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About
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Research Areas
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Catalysis for Biomass Conversion
  • Coastal wetland ecosystem dynamics
  • Subcritical and Supercritical Water Processes
  • Thermochemical Biomass Conversion Processes
  • Electrospun Nanofibers in Biomedical Applications
  • Catalytic Processes in Materials Science
  • Advanced Photocatalysis Techniques
  • Coastal and Marine Dynamics
  • TiO2 Photocatalysis and Solar Cells
  • Supramolecular Self-Assembly in Materials
  • Amino Acid Enzymes and Metabolism
  • biodegradable polymer synthesis and properties
  • Natural product bioactivities and synthesis
  • Protist diversity and phylogeny
  • Peatlands and Wetlands Ecology
  • Ginseng Biological Effects and Applications
  • Diatoms and Algae Research
  • Virus-based gene therapy research
  • Landfill Environmental Impact Studies
  • Coal and Its By-products
  • Microbial bioremediation and biosurfactants
  • Electrochemical Analysis and Applications
  • Chemokine receptors and signaling

Ocean University of China
2025

Tsinghua University
2007-2024

Center for Life Sciences
2024

Jilin Agricultural University
2024

Peking University
2023

University Town of Shenzhen
2018

Wenzhou Medical University
2015

China Jiliang University
2015

Beijing University of Technology
2009

Tianjin Tanggu Women and Child Health
2008

A new route to synthesize V-doped and V−N codoped titania nanocatalysts using a novel two-phase hydrothermal method applied in hazardous PCP−Na decomposition was reported. The physicochemical properties were characterized, indicating that the crystallite surface area increased after both first (FH) V impregnation second (SH) N implantation, whereas mesoporous framework shrinkage enlargement resulted from FH SH, respectively. ICP EPR demonstrated SH did not alter content, but rather it...

10.1021/jp110814b article EN The Journal of Physical Chemistry C 2011-03-03

Currently, the clinical application of protein/peptide therapeutics is mainly limited to modulation diseases in extracellular spaces. Intracellular targets are hardly accessed, owing largely endosomal entrapment internalized proteins/peptides. Here, we report a strategy design and construct peptides that enable endosome-to-cytosol delivery based on an extension "histidine switch" principle. By substituting Arg/Lys residues cationic cell-penetrating (CPPs) with histidine, obtained...

10.1002/anie.202304692 article EN Angewandte Chemie International Edition 2023-06-07

Intracellular delivery of biologicals such as peptides, proteins, and nucleic acids presents a great opportunity for innovative therapeutics. However, the endosome entrapment remains major bottleneck in intracellular biomacromolecules, largely limiting their therapeutic potential. Here, we converted cell-penetrating peptide (CPP), low molecular weight protamine (LMWP), to endosomal escape peptides (EEPs) by masking LMWP with pH-responsive counter-ionic peptide. The resulting masked CPPs...

10.1016/j.apsb.2024.06.022 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2024-06-26

A combined supercritical and subcritical process for pretreatment hydrolysis of lignocellulosic waste has been proposed. Batch experiments kinetic analysis were performed to investigate the secondary cellulose in water as well feasibility combining whole process. 60 mg amount microcrystalline 2.5 mL deionized mixed each reactor reacted at 380 °C 16 s primary hydrolysis, followed by different conditions hydrolysis. The products analyzed HPLC, which showed that produced 28.1% oligosaccharides...

10.1021/es803122f article EN Environmental Science & Technology 2009-02-04

The digestibility of sorted municipal solid waste (MSW) is often limited by the high content structured green waste. objectives this study are to investigate effect alkaline hydrothermal pretreatment on anaerobic digestion and analyze biogas production different parts was hydrothermally pretreated in a dilute alkali solution. hydrolysis product then incubated 500 mL saline bottle determine biochemical methane potential (BMP) under mesophilic conditions. optimum condition 170°C at 4 g NaOH/...

10.1016/s1007-0214(09)70054-9 article EN Tsinghua Science & Technology 2009-05-29

Herein, we genetically encode an esterified glutamic acid analogue (BnE) into proteins, and demonstrate that BnE can be applied in different types of site-specific protein modifications.

10.1039/d1sc01882e article EN cc-by-nc Chemical Science 2021-01-01

Abstract Diatoms synthesize silica cell walls (frustules) with genetically encoded morphologies, ranging from nanopatterns to micropatterns, that far exceed current synthetic chemistry. Silaffins, a family of phosphoproteins undergoing complex post-translational modifications, have been isolated frustules and shown facilitate regulate biosilica formation in vitro long-chain polyamines. However, their particular role frustule morphogenesis functionality remains unclear. In this study,...

10.1101/2024.12.20.629074 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-12-20

Abstract Mangroves are expanding poleward along coastlines globally as a response to rising temperatures and reduced incidence of freezing under climate change. Yet, knowledge mangrove responses infrequent cold events in the context warming regional nitrogen (N)-enriched eutrophication is limited. We conducted mesocosm experiment which seedlings two species ( A. marina B. gymnorrhiza ) were grown either at ambient temperature or with without (N) loading. During short winter period, an...

10.1088/2515-7620/ab7a77 article EN cc-by Environmental Research Communications 2020-02-28

Triangular silver nanoplates with its border size of 100±10nm and thickness 30nm were synthesized by a chemical method. These triangular characterized TEM, UVVis spectroscopy xrays diffraction analysis. Results obtained showed that these are perfect sharp corners selfassembled into twodimensional ordered monolayer on the carboncovered copper grid due to adsorption organic molecules in between nanoplates. The wellaligned film Si (100) substrate strong surfaceenhanced Raman scattering...

10.7498/aps.54.1452 article EN cc-by Acta Physica Sinica 2005-01-01

Inter-root microorganisms are major factors influencing the formation of high-quality herbs and promoting accumulation secondary metabolites, this relationship has been well characterised in many supra-herbal medicinal herbs, but there is limited information on whether ginseng saponin mediated by different forest types.Inter-root soil samples were collected from four types (Theropencedrymion, Larch forest, Broad-leaved Camphor pine forest) mountainous areas Jingyu County, Jilin Province,...

10.2139/ssrn.4839289 preprint EN 2024-01-01

<title>Abstract</title> Inter-root microorganisms are major factors influencing the formation of high-quality herbs and promoting accumulation secondary metabolites, this relationship has been well characterised in many supra-herbal medicinal herbs, but there is limited information on whether ginseng saponin mediated by different forest types.Inter-root soil samples were collected from four types (Theropencedrymion, Larch forest, Broad-leaved Camphor pine forest) mountainous areas Jingyu...

10.21203/rs.3.rs-4487770/v1 preprint EN cc-by Research Square (Research Square) 2024-06-13
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