A5067533869- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Ion channel regulation and function
- Cardiac Arrhythmias and Treatments
- Cardiac Arrest and Resuscitation
- Biotechnology and Related Fields
- Neuroscience and Neuropharmacology Research
- Heart Rate Variability and Autonomic Control
- 3D Printing in Biomedical Research
- Neuroscience and Neural Engineering
- Respiratory Support and Mechanisms
- Pluripotent Stem Cells Research
- Viral Infections and Immunology Research
- Non-Invasive Vital Sign Monitoring
- Cardiac Ischemia and Reperfusion
- Cardiomyopathy and Myosin Studies
- COVID-19 and healthcare impacts
IRCCS Istituto Auxologico Italiano
2022-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2025
Policlinico San Matteo Fondazione
2020
Istituti Ospitalieri di Cremona
2020
Abstract Aims An increase in out-of-hospital cardiac arrest (OHCA) incidence has been reported the very early phase of COVID-19 epidemic, but a clear demonstration correlation between increased OHCA and is missing so far. We aimed to verify whether there an association difference compared with 2019 epidemic curve. Methods results included all consecutive OHCAs which occurred Provinces Lodi, Cremona, Pavia, Mantova 2 months following first documented case Lombardia Region them those same time...
Abstract Background and Aims Risk scores are proposed for genetic arrhythmias. Having in 2010 one such score (M-FACT) the long QT syndrome (LQTS), this study aims to test whether adherence its suggestions would be appropriate. Methods LQT1/2/3 genotype-negative patients without aborted cardiac arrest (ACA) before diagnosis or events (CEs) below age 1 were included study, focusing on an M-FACT ≥2 (intermediate/high risk), either at presentation (static) during follow-up (dynamic), previously...
Despite major advances in the clinical management of long QT syndrome, some patients are not fully protected by beta-blocker therapy. Mexiletine is a well-known sodium channel blocker, with proven efficacy channel-mediated syndrome type 3. Our aim was to evaluate mexiletine 2 (LQT2) using cardiomyocytes derived from patient-specific human induced pluripotent stem cells, transgenic LQT2 rabbit model, and LQT2.
This essay stems from a controversial recommendation present in the 2022 European Guidelines which indicated appropriateness of considering an implantable cardioverter defibrillator (ICD) implant even for still asymptomatic long QT syndrome (LQTS) patients deemed to be at high risk by 1-2-3 LQTS score based on QTc and genotype calculated prior institution therapy. As 15 years ago, we also had proposed, but never used, called M-FACT identify appropriate ICD shock, felt responsibility...
Abstract Brugada Syndrome (BrS) is one of the most common channelopathies and related to an increased risk ventricular arrhythmias. Current guidelines recommend implantation a Cardiac Defibrillator (ICD) in those patients that have diagnostic ECG pattern history aborted cardiac arrest. Nevertheless, management asymptomatic patients, who are majority, remains controversial as their stratification often based on results inductive Electrophysiologic Study (EPS) predictive accuracy which...