- Cardiac Arrest and Resuscitation
- Heart Rate Variability and Autonomic Control
- Trauma and Emergency Care Studies
- Cardiac electrophysiology and arrhythmias
- Hemodynamic Monitoring and Therapy
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- Cardiovascular Effects of Exercise
- Sepsis Diagnosis and Treatment
- Non-Invasive Vital Sign Monitoring
- ECG Monitoring and Analysis
- Respiratory Support and Mechanisms
- Emergency and Acute Care Studies
- Cardiac Arrhythmias and Treatments
- Healthcare Technology and Patient Monitoring
- Cardiac Health and Mental Health
- Climate Change and Health Impacts
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Antiplatelet Therapy and Cardiovascular Diseases
- Receptor Mechanisms and Signaling
- Air Quality and Health Impacts
- Acute Ischemic Stroke Management
- Cardiac Imaging and Diagnostics
Foundation Center
2025
Policlinico San Matteo Fondazione
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
University of Pavia
2022-2024
Azienda Regionale Emergenza Urgenza
2022-2024
Aziende Socio Sanitarie Territoriale Lodi
2024
Advanced Research Projects Agency - Energy
2024
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2024
PHARM (Italy)
2024
Azienda Ospedaliera Ospedale Civile di Legnano
2024
Out-of-Hospital Cardiac Arrest and Covid-19 From February 21 through April 1, 2019, a total of 229 cases out-of-hospital cardiac arrest were reported in four provinces Lombardy, Italy. During...
Abstract Aims An increase in out-of-hospital cardiac arrest (OHCA) incidence has been reported the very early phase of COVID-19 epidemic, but a clear demonstration correlation between increased OHCA and is missing so far. We aimed to verify whether there an association difference compared with 2019 epidemic curve. Methods results included all consecutive OHCAs which occurred Provinces Lodi, Cremona, Pavia, Mantova 2 months following first documented case Lombardia Region them those same time...
Abstract Background and Aims An electrical storm (ES) is a clinical emergency with paucity of established treatment options. Despite initial encouraging reports about the safety effectiveness percutaneous stellate ganglion block (PSGB), many questions remained unsettled evidence from prospective multicentre study was still lacking. For these purposes, STAR designed. Methods This observational enrolling patients suffering an ES refractory to standard 1 July 2017 30 June 2023. The primary...
Electrocardiography (ECG) is an important tool to triage patients with out-of-hospital cardiac arrest (OHCA) after return of spontaneous circulation (ROSC). An immediate coronary angiography ROSC recommended only in ECG that diagnostic ST-segment elevation myocardial infarction (STEMI). To date, the benefit this approach has not been demonstrated a post-ROSC STEMI.To assess whether time from acquisition associated accuracy for STEMI.This retrospective, multicenter cohort study (the Post-ROSC...
The Utstein Based-ROSC (UB-ROSC) score has been developed to predict ROSC in OHCA victims. Aim of the study was validate UB-ROSC using two Utstein-based registries: SWiss REgistry Cardiac Arrest (SWISSRECA) and Lombardia Registry (Lombardia CARe), northern Italy.
Introduction An increase in the incidence of OHCA during COVID-19 pandemic has been recently demonstrated. However, there are no data about how epidemic influenced treatment victims. Methods We performed an analysis Lombardia Cardiac Arrest Registry comparing all OHCAs occurred Provinces Lodi, Cremona, Pavia and Mantua (northern Italy) first 100 days with those same period 2019. Results The were 694 2020 520 Bystander cardiopulmonary resuscitation (CPR) rate was lower (20% vs 31%, p<0.001),...
Abstract Aims Electrical storm (ES) is a life-threatening condition requiring rapid management. Percutaneous stellate ganglion block (PSGB) proved to be safe and effective on top of standard therapy, but no data are available about its early use. Methods results We considered all patients enrolled from 1 July 2017 30 April 2024 in the STAR registry (STellate for Arrhythmic stoRm), multicentre, international, observational, prospective registry. aimed assess effectiveness first PSGB only....
Devices for mechanical cardiopulmonary resuscitation (CPR) are recommended when high quality CPR cannot be provided. Different devices available, but the literature is poor in direct comparison studies. Our aim was to assess whether type of chest compressor could affect probability return spontaneous circulation (ROSC) and 30-day survival Out-of-Hospital Cardiac Arrest (OHCA) patients as compared manual standard CPR.We considered all OHCAs that occurred from 1 January 2015 31 December 2022...
Evidence of the association between AMplitude Spectral Area (AMSA) ventricular fibrillation and outcome after out-of-hospital cardiac arrest (OHCA) is limited to short-term follow-up. In this study, we assess whether AMSA can stratify risk death or poor neurological at 30 days 1 year OHCA in patients with an initial shockable rhythm non-shockable converted a one. This multicentre retrospective study prospectively collected data two European Utstein-based registries. We included all cases...
Background Pollution has been suggested as a precipitating factor for cardiovascular diseases. However, data about the link between air pollution and risk of out-of-hospital cardiac arrest (OHCA) are limited controversial. Methods By collecting both in OHCA registry database regional agency environmental protection (ARPA) Lombardy region, all medical OHCAs mean daily concentration pollutants including fine particulate matter (PM 10 , PM 2.5 ), benzene (C 6 H carbon monoxide (CO), nitrogen...
Background Once the return of spontaneous circulation after out-of-hospital cardiac arrest is achieved, a 12-lead ECG strongly recommended to identify candidates for urgent coronary angiography. has no apparent role in mortality risk stratification. We aimed assess whether features could be associated with 30-day survival patients arrest. Methods and Results All post-return ECGs from January 2015 December 2018 3 European centers (Pavia, Lugano, Vienna) were collected. Prehospital data...
Background: Cangrelor provides rapid platelet inhibition, making it a potential option for out-of-hospital cardiac arrest (OHCA) survivors undergoing percutaneous coronary intervention (PCI). However, clinical data on its use after OHCA are limited. This study investigates in-hospital outcomes of cangrelor in this population. Methods: We conducted prospective, observational involving patients from the Lombardia CARe Registry (January 2015–December 2022) who underwent PCI seven centers...
The relationship between COVID-19 and out-of-hospital cardiac arrests (OHCAs) has been shown during different phases of the first pandemic wave, but little is known about how to predict where will increase in case a third peak.To seek for correlation OHCAs daily incidence both two waves at provincial level.We considered all occurred provinces Pavia, Lodi, Cremona, Mantua Varese, Lombardy Region (Italy), from 21/02/2020 31/12/2020. We divided study period into 1, 157 days after outbreak...
Background: No data are available regarding long-term survival of out-of-hospital cardiac arrest (OHCA) patients based on different Utstein subgroups, which expected to significantly differ in terms survival. We aimed provide the first analysis OHCA divided according categories. Methods: analyzed all 4,924 cases prospectively enrolled Lombardia Cardiac Arrest Registry (Lombardia CARe) from 2015 2019. Pre-hospital data, survival, and cerebral performance category score (CPC) at 1, 6, 12...
Objective Antiarrhythmic drugs are recommended for out of hospital cardiac arrest (OHCA) with shock-refractory ventricular fibrillation (VF). Amplitude Spectral Area (AMSA) VF is a quantitative waveform measure that describes the amplitude-weighted mean frequency VF, it correlates intramyocardial adenosine triphosphate (ATP) concentration, predictor shock efficacy and an emerging indicator to guide defibrillation resuscitation efforts. How AMSA might be influenced by amiodarone...
Background. The survival benefit of complete versus infarct-related artery (IRA)-only revascularization during the index hospitalization in patients resuscitated from an out-of-hospital cardiac arrest (OHCA) with multivessel disease is unknown. Methods. We considered all OHCA prospectively enrolled Lombardia Cardiac Arrest Registry (Lombardia CARe) 1 January 2015 to May 2021 who underwent coronary angiography (CAG) at Fondazione IRCCS Policlinico San Matteo (Pavia). Patients’ prehospital,...