A5006984986- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- COVID-19 diagnosis using AI
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- COVID-19 Clinical Research Studies
- Cardiac Valve Diseases and Treatments
- Clinical Reasoning and Diagnostic Skills
- SARS-CoV-2 and COVID-19 Research
- Machine Learning in Healthcare
- COVID-19 and healthcare impacts
- Infective Endocarditis Diagnosis and Management
- ECG Monitoring and Analysis
- Healthcare Systems and Technology
- Sepsis Diagnosis and Treatment
- Phonocardiography and Auscultation Techniques
- Central Venous Catheters and Hemodialysis
- Lung Cancer Diagnosis and Treatment
- Brain Tumor Detection and Classification
- Intelligent Tutoring Systems and Adaptive Learning
- Radiomics and Machine Learning in Medical Imaging
Clinique Pasteur
2023-2025
Hôpital Cardiologique du Haut-Lévêque
2024-2025
Electrophysiology and Heart Modeling Institute
2024-2025
Centre Hospitalier Universitaire de Bordeaux
2024-2025
Université de Bordeaux
2024-2025
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2025
IRCCS Istituto Auxologico Italiano
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2024
Vrije Universiteit Brussel
2024
Bordeaux Population Health
2024
Pulsed field ablation (PFA) is a new, non-thermal modality for pulmonary vein (PV) isolation in patients with atrial fibrillation (AF). The multi-centre EUropean Real World Outcomes Field AblatiOn Patients Symptomatic AtRIAl Fibrillation (EU-PORIA) registry sought to determine the safety, efficacy, and learning curve characteristics pentaspline, multi-electrode PFA catheter.All-comer AF from seven high-volume centres were consecutively enrolled. Procedural follow-up data collected. Learning...
Abstract Aims Pulsed field ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We describe multicentre experience on pulmonary vein isolation (PVI) via the pentaspline Farapulse™ PFA system vs. thermal-based technologies in propensity score-matched population of paroxysmal atrial fibrillation (PAF) patients. Methods and results Propensity score matching was adopted compare PVI-only outcomes Farawave™ (Group PFA), cryoballoon CRYO), or focal...
BACKGROUND: Pulsed field ablation (PFA) is increasingly used in clinical practice for the treatment of atrial fibrillation. While susceptibility erythrocytes to electroporation well established, effect cardiac PFA technologies on hemolysis has remained underreported. The aim this study was investigate incidence, severity, and impact PFA-induced hemolysis. METHODS: We included n=145 patients undergoing fibrillation catheter with a pentaspline (biphasic, bipolar pulses 2 kV) n=70 receiving...
Abstract Aims The aim of this study was to compare procedural efficacy and safety, including 1-year freedom from AF recurrence, between the novel cryoballoon system PolarX (Boston Scientific) Arctic Front Advance Pro (AFA-Pro) (Medtronic), in patients with paroxysmal undergoing PVI. Methods results This multicentre prospective observational included 267 consecutive a first cryoablation procedure for (137 PolarX, 130 AFA-Pro). Kaplan-Meier curves log-rank test used recurrence both groups....
We sought to examine the association of epicardial adipose tissue (EAT) quantified on chest computed tomography (CT) with extent pneumonia and adverse outcomes in patients coronavirus disease 2019 (COVID-19).
Abstract Background and Aims Pulmonary vein isolation (PVI) is the most effective rhythm control strategy in paroxysmal atrial fibrillation (AF). Pulsed field ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We report first multicenter experience on PVI via pentaspline FarapulseTM PFA system versus thermal-based technologies propensity score-matched population of AF patients. Methods Propensity score matching was adopted compare PVI-only...
Background Shortage of human resources, increasing educational costs, and the need to keep social distances in response COVID-19 worldwide outbreak have prompted necessity clinical training methods designed for distance learning. Virtual patient simulators (VPSs) may partially meet these needs. Natural language processing (NLP) intelligent tutoring systems (ITSs) further enhance impact simulators. Objective The goal this study was develop a VPS diagnostic reasoning that integrates...
Abstract Aims In functional tricuspid regurgitation (FTR) patients, leaflet tethering and relatively low jet velocity could result in proximal flow geometry distortions that lead to underestimation of TR. Application correction factors on two-dimensional (2D) isovelocity surface area (PISA) equation may increase its reliability. This study sought evaluate the impact corrected 2D PISA method quantifying FTR severity. Methods results 102 patients with FTR, we compared both conventional...
electroporation ◼ isosorbide dinitrate nitrates
Purpose To examine the independent and incremental value of CT-derived quantitative burden attenuation coronavirus disease 2019 (COVID-19) pneumonia for prediction clinical deterioration or death. Materials Methods This was a retrospective analysis prospective international registry consecutive patients with laboratory-confirmed COVID-19 chest CT imaging, admitted to four centers between January 10 May 6, 2020. Total (expressed as percentage) mean ground-glass opacities (GGO) consolidation...
Abstract The main aim of the present study was to psychophysically evaluate smell and taste functions in hospitalized COVID-19 patients compare those results with a group healthy subjects. Another assess relationship changes patients’ number clinical parameters, symptoms, other physiological signs as well severity disease. Olfactory gustatory were tested 61 positive for SARS-CoV-2 infection control 54 individuals. Overall, we found significant impairment olfactory compared group. Indeed,...
Arrhythmogenic cardiomyopathy is a heart disease in which the muscle replaced by scar tissue. This main substrate for development of malignant ventricular arrhythmias. Sudden cardiac death most common manifestation and can often be first sign disease, especially young people. Correct stratification arrhythmic risk essential management these patients but remains challenge clinical cardiologist. In this context, aim our work was to review literature analyse important studies new developments...
Enrollment of large cohorts syncope patients from administrative data is crucial for proper risk stratification but limited by the enormous amount time required manual revision medical records.To develop a Natural Language Processing (NLP) algorithm to automatically identify Emergency Department (ED) electronic records (EMRs).De-identified EMRs all consecutive evaluated at Humanitas Research Hospital ED 1 December 2013 31 March 2014 and 2015 2016 were manually annotated syncope. Records...
Abstract Predicting clinical deterioration in COVID-19 patients remains a challenging task the Emergency Department (ED). To address this aim, we developed an artificial neural network using textual (e.g. patient history) and tabular laboratory values) data from ED electronic medical reports. The predicted outcomes were 30-day mortality ICU admission. We included consecutive Humanitas Research Hospital San Raffaele Milan area between February 20 May 5, 2020. 1296 patients. Textual predictors...
wide antral pulmonary vein isolation (PVI) is effective for treating paroxysmal atrial fibrillation (PAF), although time-demanding. We investigated the impact of a standardized ablation protocol by using bidirectional transeptal steerable sheath, high-density mapping and very high-power-short-duration (vHPSD) catheters on procedure timing, efficacy, safety. consecutive PAF patients free from previous ablations undergoing PVI alone between January 2022 March 2023 were prospectively enrolled....
Real-life data on efficacy and safety of pulsed-field ablation (PFA) using the pentaspline multi-electrode catheter in symptomatic atrial fibrillation (AF) patients is still scarce. This study aims to assess PFA with persistent AF. Data from early commercial use across seven European centers were collected a registry. To confirm extra pulmonary vein (PV) ablation, categorized into two groups: those undergoing isolation (PVI) alone receiving additional ablation. Procedural follow-up...
Abstract Background Pulsed-field ablation is a novel non-thermal modality which being increasingly used in clinical practice for the treatment of atrial fibrillation (AF). While susceptibility erythrocytes to electroporation well-established, effect cardiac PFA technologies on erythrocyte destruction has not been described so far. Purpose The aim this study was investigate whether induces clinically significant hemolysis. Methods We included 187 patients undergoing AF catheter with either...