A5101625588- Aquaculture Nutrition and Growth
- Aquatic life and conservation
- Ginseng Biological Effects and Applications
- Gut microbiota and health
- Aquaculture disease management and microbiota
- Inflammatory Bowel Disease
- Polysaccharides and Plant Cell Walls
- Breast Cancer Treatment Studies
- Pharmacological Effects of Natural Compounds
- Dendrimers and Hyperbranched Polymers
- Wastewater Treatment and Nitrogen Removal
- Natural product bioactivities and synthesis
- Cancer, Hypoxia, and Metabolism
- Aquatic Ecosystems and Phytoplankton Dynamics
- Hippo pathway signaling and YAP/TAZ
- Microscopic Colitis
- Cephalopods and Marine Biology
- Curcumin's Biomedical Applications
- Muscle Physiology and Disorders
- MicroRNA in disease regulation
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Immune Cell Function and Interaction
- PI3K/AKT/mTOR signaling in cancer
- Metal-Organic Frameworks: Synthesis and Applications
Dalian Polytechnic University
2019-2025
Ministry of Agriculture and Rural Affairs
2016-2024
Chinese Academy of Fishery Sciences
2016-2024
First Affiliated Hospital Zhejiang University
2019-2024
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2024
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2024
Zhejiang University
2011-2023
Chongqing Medical University
2022-2023
Soochow University
2022
Sanya University
2022
Background: Activation of the thermogenic program in white and brown adipocytes presents a promising avenue for increasing energy expenditure during treatment obesity. The endogenous mechanism promoting thermogenesis or browning has indicated that gut microbiota is crucial regulator host balance. However, whether effects therapeutic intervention-induced modulation on adipocyte involved regulation leptin remains unclear. Method: adipose features were analyzed by body composition analysis,...
Intestinal immune dysfunction and gut microbiota dysbiosis are critically causative factors in the pathogenesis of ulcerative colitis (UC); however, current first-line drugs for UC treatment clinics often remain great challenges due to their nontargeting therapeutic efficacy severe side effects. In study, colon-targeting nanoparticles based on Angelica sinensis polysaccharide with pH- redox-responsiveness were fabricated specifically release naturally active compound ginsenoside Rh2 colonic...
Nonalcoholic fatty liver disease (NAFLD) is an obesity-related comorbidity, and it characterized as a spectrum of abnormalities, including inflammation, steatosis, fibrosis. The gut-liver axis implicated in the pathogenesis development NAFLD. A promising drug agent targeting expected to reverse NAFLD.We utilized high-fat diet (HFD)-induced obese mice obesity-prone Lepob examine regulation natural medicine Panax Notoginseng Saponins (PNS) on NAFLD.PNS exhibited potent anti-lipogenesis...
Although increasing attention has been attracted to the study and application of biofloc technology (BFT) in aquaculture, few details have reported about bacterial community its manipulation strategy for commercial shrimp production. An 8-week trial was conducted investigate effects three input C/N ratios (8:1, 12:1 16:1) on water gut a BFT tank system with intensive aquaculture P. vannamei. Each ratio group had randomly assigned replicate tanks (culture volume 30 m3), each stocked juvenile...
It has long been held as scientific fact that soon after birth, cardiomyocytes cease dividing, thus explaining the limited restoration of cardiac function a heart attack. Recent demonstrations myocyte differentiation observed in vitro or vivo transplantation adult stem cells from blood, fat, skeletal muscle, have challenged this view. Analysis these studies complicated by large disparity magnitude effects seen different groups and obscured recently appreciated process stem-cell fusion. We...
To assess the effect of addition probiotics and carbon source on microbial community structure within shrimp culture, an enclosure system simulating a high density, intensive aquaculture Litopenaeus vannamei was set up in Dianbai, Maoming, Guangdong province, China. The phylogenetic profiles communities after Bacillus molasses were studied middle final culture season (on 45th, 75th 95th day) using polymerase chain reaction-denaturing gradient gel electrophoresis. A total four groups, each...
In the contemporary era, heightened emphasis on health and safety has emerged as a paramount concern among individuals with food.
This study aims to develop and assess the therapeutic potential of oleanolic acid nanoparticles (OA NPs) in treating ulcerative colitis (UC). OA NPs were synthesized using an emulsion solvent evaporation method, forming spherical with average diameter 138.1 nm. The designed target colon through enhanced permeability retention (EPR) effect. Network pharmacology molecular docking identified key inflammatory pathways, vitro (RAW264.7 cells) vivo (DSS-induced UC mouse model) experiments...
Ammonia is the main pollution factor of aquatic environment in marine shrimp culture systems. In order to demonstrate feasibility combination biofloc technology and nitrifying biofilter for ammonia removal, a 70-day production trial was conducted simplified pilot-scale hybrid biofloc-based recirculating aquaculture system (biofloc-RAS) with intensive Litopenaeus vannamei. Nitrogen dynamics microbial communities were investigated three replicated systems simultaneously under conditions high...
Acute liver injury (ALI) is a severe health condition with limited treatment options. Phlorotannin (PT), natural compound extracted from seaweeds, has shown potential in improving function. However, its poor stability and bioavailability have applications vivo. In this study, we developed PT-based nanoparticles (NPs) through Mannich reaction glycine, which exhibited good biocompatibility prolonged circulation time Our results revealed that the PT NPs possess strong free radical scavenging...