Q L Zhang

ORCID: 0009-0006-4849-4646
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About
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Research Areas
  • Chronic Lymphocytic Leukemia Research
  • Genetic Mapping and Diversity in Plants and Animals
  • Genetics and Plant Breeding
  • Herpesvirus Infections and Treatments
  • Liver Disease Diagnosis and Treatment
  • Genetic and phenotypic traits in livestock
  • Viral-associated cancers and disorders
  • Lung Cancer Research Studies
  • Toxin Mechanisms and Immunotoxins
  • Cancer Immunotherapy and Biomarkers
  • Neuroendocrine Tumor Research Advances
  • Pharmacological Effects of Natural Compounds
  • Lymphoma Diagnosis and Treatment

Shanghai Normal University
2024

Affiliated Hospital of Hangzhou Normal University
2020-2023

Sichuan University
2021

Understanding how numerous quantitative trait loci (QTL) shape phenotypic variation is an important question in genetics. To address this, we established a permanent population of 18,421 (18K) rice lines with reduced structure. We generated reference-level genome assemblies the founders and genotyped all 18K-rice through whole-genome sequencing. Through high-resolution mapping, 96 high-quality candidate genes contributing to 16 traits were identified, including

10.1126/science.adm8762 article EN Science 2024-07-04

Immune checkpoint inhibitor (ICI) has been emerged as a major breakthrough in tumor immunotherapy, but its unique mechanism of action also led to number immune-related adverse events (irAE). Type 1 diabetes mellitus (T1DM) is one the rarest irAEs. This paper reports case advanced malignant liver tumor-induced T1DM who received second-line anti-PD-1 therapy and showed initial symptoms hyperosmolar coma hyperglycemia. In addition, relevant literature at home abroad was collected reviewed,...

10.3760/cma.j.cn501113-20191124-00430 article EN PubMed 2020-06-20

Objective: To investigate the incidence of high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangement in Chinese diffuse large (DLBCL) . Methods: From January 2013 to August 2020, 922 DLBCL cases were collected. C-MYC protein expression levels analyzed by immunohistochemistry staining. Fluorescence situ hybridization was used detect structural abnormalities MYC, BCL2, BCL6, including gene breaks copy number changes. Results: found 29 out (3.15%) , 25 double-hit (DHL; 14 involving...

10.3760/cma.j.issn.0253-2727.2021.02.006 article EN PubMed 2021-02-14

To explore the relationship between liver iron deposition and steatosis in patients with non-alcoholic fatty disease (NAFLD) through MRI.

10.3760/cma.j.cn501113-20230902-00086 article EN PubMed 2023-11-20
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