A5101976750- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Polymer Science and PVC
- Synthesis and Characterization of Heterocyclic Compounds
- Inorganic and Organometallic Chemistry
- Molecular Sensors and Ion Detection
- Electrochemical Analysis and Applications
- Surfactants and Colloidal Systems
- Synthesis and Biological Evaluation
- Thermodynamic properties of mixtures
- Electrochemical sensors and biosensors
- Microwave-Assisted Synthesis and Applications
- Thermal and Kinetic Analysis
- Veterinary Oncology Research
- Synthesis of Tetrazole Derivatives
- Conducting polymers and applications
- Water Governance and Infrastructure
- Quinazolinone synthesis and applications
- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- Spam and Phishing Detection
- Analytical Chemistry and Sensors
- South Asian Studies and Conflicts
- Digital Marketing and Social Media
- Infectious Diseases and Mycology
Shri Mata Vaishno Devi University
2018-2023
Lovely Professional University
2020-2023
Punjab Technical University
2022-2023
Kerala Veterinary and Animal Sciences University
2021
Sri Guru Granth Sahib World University
2018
Division of Chemistry
2018
Guru Nanak Dev University
2017
Indian Institute of Integrative Medicine
2016-2017
Thapar Institute of Engineering & Technology
2012-2016
Government Medical College
2015-2016
We have used boron-based molecules to create novel, competitive, reversible inhibitors of phosphodiesterase 4 (PDE4). The co-crystal structure reveals a binding configuration which is unique compared classical catechol PDE4 inhibitors, with boron the activated water in bimetal center. These phenoxybenzoxaboroles can be optimized generate submicromolar potency enzyme inhibit TNF-α, IL-2, IFN-γ, IL-5 and IL-10 activities vitro show safety efficacy for topical treatment human psoriasis. They...
Screening for EGFR mutation is a key molecular test management of lung cancer patients. Outcome patients with receiving tyrosine kinase inhibitor known to be better across different ethnic populations. However, frequency mutations and the clinical response in most other populations, including India, remains explored. We conducted retrospective analysis Indian who were managed oral inhibitors. Majority study had adenocarcinoma non-smokers. 39/111 tested positive domain determined by Taqman...
study population twice, so these studies are arguably contributing more weight to the overall effect size than appropriate.Despite concerns raised, we acknowledge that meta-analysis presented by Cong et al (2014) has drawn attention potential role of sedentary behaviour in colon and rectal cancer aetiology.Clearly further studies, using well-designed tested measures behaviour, required this field.
The development of generic drugs presents a unique set challenges, particularly in navigating the complex landscape pharmaceutical patents while ensuring bioequivalence and physical/chemical stability, comparison to innovator counterparts. Solid-state forms, including polymorphs, pseudopolymorphs, cocrystals, coamorphous play pivotal role addressing these challenges. Each solid forms provides benefits solubility, manufacturability, all which are crucial for gaining regulatory approval market...
Objective: Product knowledge is the depth of understanding a consumer, particularly those who shop online, has about particular brand or product. The primary goal this study was to determine how product presentation and information related online buyers' decisions buy are related. Theoretical Framework: This based on Consumer Decision-Making Model Elaboration Likelihood Model, bringing light relationship between knowledge, presentation, purchase in shopping. familiarity would affect...
The neo-liberal market-driven economy has been affecting the and people of India in various ways. One directly visible impact is agenda transforming a few large cities into so-called 'world-class cities' as hubs operation trans-national capital business. Such urban renewal resulting further segregation citizens elite class, who are settling well-serviced gated settlements, majority poor, being driven out from core parts to peripheries. This 'enclave urbanism', logic expansion revival...
A novel green and energy-efficient synthesis of 2,3-dihydro/spiroquinazolin-4(1<i>H</i>)-ones via three-component cyclocondensation reaction involving isatoic anhydride, amines aldehydes/ketones utilizing recyclable tartaric acid–SDS catalyst system has been achieved. With simple requirements mechanical stirring or mechanochemical activation at room temperature one the shortest reported times as yet, it is a significant improvement on previously described methods for such compounds....
P. Biginelli reported the synthesis of functionalized 3, 4 dihydropyrimidine‐2 (1 H )‐ones via three component condensation an aromatic aldehyde, urea and ethylacetoacetate. This multicomponent reaction is much importance due to excellent pharmacological properties dihydropyrimidines. In this account, we synthesized some halo substituted indole dihydropyrimidines evaluated their antimicrobial activity. The minimum inhibitory concentration (MIC) was determined by micro dilution technique in...
Among several issues that Indian society confronts today, involuntary displacement of people by government due to taking away their agricultural lands and other assets (homestead etc.) for development projects—both in public or private sectors—has emerged as one the highly debated disputed issue. Several these projects have faced stiff resistance even violent agitations against appropriation affected people’s under compulsive Land Acquisition Act, 1894. In earlier decades (since India’s...
An efficient synthesis of melamine‐formaldehyde resin has been achieved using conventional as well microwave irradiations (without and with solid support) in different molar ratio. Resin samples were tested for their chemical physical properties. The structure all the supported by spectral data
Differential pulse voltammetric studies on <bold>DPE-I</bold> and <bold>DPE-II</bold> indicating selective response to Fe<sup>3+</sup>, supported by DFT using Gaussian software.
Compounds 3-(2,4-dinitrophenoxy)phenol (L1) and 3-(2-nitrophenoxy)phenol (L2) were synthesized with high yield characterized by spectroscopic techniques. The complexation behavior of L1 L2 for different anionic species (CN−, F−, Cl−, Br−, AcO−, I−, HSO4−, OH−, H2PO4−, ClO4−) in acetonitrile medium investigated. showed degree selectivity fluoride over other anions. This could be easily observed the naked eye, indicating that is a potential colorimetric sensor anion. Differential pulse...
<bold>TPEI</bold>is a novel photometric chemosensor for visual detection of cobalt/fluoride/cyanide ions.
Multi-component domino approaches are attracting significant interest due to their wide application in various fields and have become one of the most efficient tools for design development a range synthetically, medically industrially important molecules. β-Oxodithioesters been widely applied organic transformations synthesis functionalized heterocycles biologically relevant This review highlights multicomponent strategies involving β-oxodithioesters, key component context preparation...
Rajasthan is western state of India. Ajmer located in the centre (INDIA) between 25° 38“ and 26° 58“ north 75° 22” east longitude covering a geographical area about 8481 sq. km hemmed all sides by Aravalli hills. About 7 miles from city Pushkar Lake created touch Lord Brahma. The Dargah Khawaja Moinuddin chisti holiest shrine next to Mecca world. has hot dry summer cold bracing winter. winter extends November February March June followed rainy season till mid-September. temperature varies...