A5031048813- Fungal and yeast genetics research
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Frailty in Older Adults
- Alzheimer's disease research and treatments
- Endoplasmic Reticulum Stress and Disease
- 14-3-3 protein interactions
- Porphyrin and Phthalocyanine Chemistry
- Metal-Catalyzed Oxygenation Mechanisms
- Colorectal Cancer Surgical Treatments
- Enhanced Recovery After Surgery
- Proteins in Food Systems
- Porphyrin Metabolism and Disorders
- Asymmetric Synthesis and Catalysis
- Palliative Care and End-of-Life Issues
- Protist diversity and phylogeny
- Molecular spectroscopy and chirality
- Cancer survivorship and care
- Biofuel production and bioconversion
- Axial and Atropisomeric Chirality Synthesis
- Family Support in Illness
- Microbial Natural Products and Biosynthesis
- Enzyme Production and Characterization
Institut Paoli-Calmettes
2024
Assistance Publique Hôpitaux de Marseille
2023
Institut Pasteur
2014-2022
Centre National de la Recherche Scientifique
2010-2019
Sorbonne Université
2010-2014
Canadian Nautical Research Society
2014
Laboratoire des Biomolécules
2014
Institut Parisien de Chimie Moléculaire
2011
Laboratoire de Chimie Organique
2010
Laboratoire de Synthèse Organique
2010
The rodlet structure present on the Aspergillus fumigatus conidial surface hides conidia from immune recognition. In spite of essential biological role rodlets, molecular basis for their self-assembly and disaggregation is not known. Analysis soluble forms conidia-extracted recombinant RodA by NMR spectroscopy has indicated importance disulfide bonds identified two dynamic regions as likely candidates conformational change intermolecular interactions during conversion into amyloid structure....
An easy round-trip of (D)-(+)-camphor enolate to a racemic mixture cationic (η6-arene)Mn(CO)3+ complexes is the base strategy adopted for first resolution such complexes. X-ray structures one (η5-cyclohexadienyl)Mn(CO)3 diastereoisomers obtained after addition chiral auxiliary as well corresponding enantiopure η6 complex rearomatization have been established. Proton-decoupled deuterium 2D NMR in polypeptide liquid crystals proved be an efficient tool determination enantiomeric purity planar...
Three "basket handle" porphyrins have been prepared by condensation of tetrakis-(α,β,α,β-2-aminophenyl)porphyrin atropoisomer with 1,1′-binaphthyl, 2,2′-dimethoxy, -3,3′-dicarbonylchloride, -3,3′-diacetylchloride and -3,3′-dipropanoylchloride. The epoxidation styrene the three iron catalysts, obtained after metalation free porphyrins, occurs good yields moderate ee up to 54%. These showed unexpected conformational differences, as revealed NMR spectroscopy. In particular, variable temperature...
In Europe, CRC is the second most common cause of cancer death, and surgery remains mainstay curative treatment. Age frailty are associated with an increased risk postoperative morbidity 1-year mortality. Chronological age not sufficient to assess complications. The CGA has been developed better identify frail patients. Geriatric co-management have optimize post-operative outcomes. We analyzed real-life geriatric within ERAS program on surgical outcomes at 90 days oncologic 1 year in...
<title>Abstract</title> In Europe, CRC is the second most common cause of cancer death, and surgery remains mainstay curative treatment. Age frailty are associated with an increased risk postoperative morbidity 1-year mortality. Chronological age not sufficient to assess complications. The CGA has been developed better identify frail patients. Geriatric co-management have optimize post-operative outcomes. We analyzed real-life geriatric within ERAS program on surgical outcomes at 90 days...