A5102486983- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Colorectal Cancer Treatments and Studies
- Phytochemistry and Biological Activities
- Bee Products Chemical Analysis
- Protein Hydrolysis and Bioactive Peptides
- Phytochemicals and Antioxidant Activities
- Lung Cancer Treatments and Mutations
- Biological and pharmacological studies of plants
- Peptidase Inhibition and Analysis
- Phytochemical compounds biological activities
- Biochemical effects in animals
- Lung Cancer Research Studies
- Medicinal plant effects and applications
- Neuroendocrine Tumor Research Advances
- Meat and Animal Product Quality
- Advanced Drug Delivery Systems
- Phytochemical and Pharmacological Studies
- Drug Transport and Resistance Mechanisms
- Pharmaceutical studies and practices
- Seaweed-derived Bioactive Compounds
- Polysaccharides and Plant Cell Walls
- Cancer Immunotherapy and Biomarkers
- Natural Compound Pharmacology Studies
Zhejiang Cancer Hospital
2024
Zhejiang Chinese Medical University
2024
Jilin University
2018-2022
Jilin University of Chemical Technology
2017-2018
Huperzine A (HupA) is a selective acetylcholinesterase inhibitor used to treat Alzheimer's disease. The existing dosage of HupA lacks brain selectivity and can cause serious side effects in the gastrointestinal peripheral cholinergic systems.The aim this study was develop characterize nanoemulsion (NE) targeted HupA-NE modified with lactoferrin (Lf) for intranasal administration.The NE formulated using pseudo-ternary phase diagrams optimized response surface methodology. Particle size...
The association between immune-related adverse events (irAEs) and survival outcomes in non-small cell lung cancer (NSCLC) patients treated with programmed death-(ligand) 1 [PD-(L)1] inhibitors remains controversial, partly due to variations dealing immortal-time bias (ITB).
Bletilla striata is widely used for stanching bleeding. In this study, polysaccharides from B. (BSP) were extracted by hot water. Four named BSP-1–BSP-4 fractionated using DEAE-52 cellulose. BSP fractions contained sulfate, and the degrees of substitution BSP-3 BSP-4 1.59 1.70, respectively. Analysis monosaccharide composition showed that four mainly composed mannan glucose. The in vitro results elicited pro-coagulant capacities shortening activating partial thromboplastin time, prothrombin...
The chemical composition and potential bioactivities of essential oil from Quercus mongolica bark (EOQMB) were researched for value-added utilization processing by-product. results gas chromatography-mass spectrometry (GC–MS) analysis showed that 30 components accounting 98.42% identified in EOQMB, with pentadecanoic acid the most abundant compound 34.90%, which was further confirmed by Fourier transform infrared observation. EOQMB exerts antioxidant activities, IC50 values scavenging DPPH...
Background: Immunotherapy blocking programmed death-1 (PD-1)/programmed death ligand-1 (PD-L1) has revolutionized the treatment of extensive-stage small-cell lung cancer (SCLC), but only with limited real-world efficacy data; evidence from immunotherapy for other pulmonary neuroendocrine carcinoma (PNEC) is scarce. Objective: The purpose this study to evaluate receiving PD-1/PD-L1 inhibitors in patients advanced PNEC and explore factors related survival prognosis, providing clues PNEC....
Abstract The chemical composition and antitumor activity of essential oil were compared for four parts the Arisaema Amuremse Maxim. Chemical constituent in every Maxim was identified by GC-MS analysis systematically. had 114 kinds oils. Tubers, petioles, leaves, fruits 53, 48, 5 21 species oil, respectively. antiproliferative against Hep2, HCT-116, A549, SW480, HepG2 cell lines been investigated MTT assay. tubers, leaves all strong activity. IC 50 19.60μg·mL -1 , 17.60μg·mL 23.80μg·mL...
Summary As food ingredient, Anser cygnoides is farmed in large scale; however, its blood underused. The characteristics, stability and antioxidant activities of P owder A . C ygnoides S erum ( FACSP ) were investigated. Results showed that was protein‐rich displayed satisfactory activities. In vitro analysis indicated the IC 50 values 2, 2′‐azinobis‐(3‐ethylbenz‐thiazoline‐6‐sulphonate), 1,1‐diphenyl‐2‐picrylhydrazyl hydroxyl radicals 1.56, 2.76 39.55 mg mL −1 , respectively. vivo experiment...