A5001922868- Dermatology and Skin Diseases
- Phytoplasmas and Hemiptera pathogens
- Cocoa and Sweet Potato Agronomy
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
- Allergic Rhinitis and Sensitization
- Plant Pathogenic Bacteria Studies
- Autoimmune Bullous Skin Diseases
- Banana Cultivation and Research
- Systemic Sclerosis and Related Diseases
- Plant Pathogens and Fungal Diseases
- Herpesvirus Infections and Treatments
- Spondyloarthritis Studies and Treatments
- Food Allergy and Anaphylaxis Research
- Inflammatory Bowel Disease
- Cerebral Venous Sinus Thrombosis
- Cancer-related molecular mechanisms research
- Nonmelanoma Skin Cancer Studies
- RNA Research and Splicing
- Immunodeficiency and Autoimmune Disorders
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- Health Systems, Economic Evaluations, Quality of Life
- Retinal and Optic Conditions
- Animal Disease Management and Epidemiology
Stony Brook School
2024-2025
Stony Brook University
2024-2025
Icahn School of Medicine at Mount Sinai
2023-2025
National Institute of Biology
2007-2009
A new real‐time PCR detection system was developed for grapevine yellows (GY) using TaqMan minor groove binder probes and including two amplicons group‐specific of Flavescence dorée (FD) Bois noir (BN) phytoplasmas, plus a universal phytoplasma amplicon. FD BN were designed to amplify species‐specific genomic DNA fragments the amplicon 16S ribosomal region. Efficiency amplification, limit detection, range linearity dynamic assessed all three amplicons. The specificity systems tested on...
Bimekizumab is a humanized monoclonal IgG1 antibody that selectively inhibits IL-17A and IL-17F, two cytokines play critical role in psoriasis vulgaris pathogenesis. Randomized clinical trials demonstrating the superiority of bimekizumab compared to placebo other injectable biologics led its approval by United States FDA for moderate-to-severe plaque psoriasis. Due often-strict inclusion/exclusion criteria randomized trials, patient characteristics real practice may drastically differ. Thus,...
Interaction between phytoplasma and grapevine at the physiological level is still poorly understood, as are plant defence mechanisms against pathogen. This study investigates of gene expression three selected genes in a large number plants belonging to six disease/cultivar groups (healthy Chardonnay, Bois noir‐infected Flavescence dorée‐infected Barbera Prosecco, recovered Prosecco). All were grown vineyards uncontrolled conditions order represent physiology disease accurately possible....
Apple proliferation (AP) phytoplasma ('Candidatus Phytoplasma mali'; Seemüller & Schneider, 2004) is the causal agent of a serious disease apple (Malus domestica). It has also been found in hazelnut (Corylus spp.) (Marcone et al., 1996), pear (Pyrus communis) and Japanese plum (Prunus salicina). In this report, AP was cherry avium), apricot (P. armeniaca) cherry, wilting, dying, floral phloem necrosis were first observed 2004 south western Slovenia. No phytoplasmas could be isolated from...
<title>Abstract</title> Biologics and Janus kinase (JAK) inhibitors are immunomodulating immunosuppressing medications, respectively, utilized to treat atopic dermatitis (AD), psoriasis (PSO), psoriatic arthritis (PsA), alopecia areata (AA). Special recommendations must be considered when prescribing vaccinations in this population, as the pneumococcal herpes zoster vaccine recommended patients ≥ 19-years-old (rather than 65-years-old 50-years-old general respectively), along with a yearly...
Atopic dermatitis (AD) is a relapsing and remitting inflammatory skin disease that can significantly impair an individual’s quality of life. Elderly-onset AD increasing in prevalence developed countries, likely due to aging populations. When refractory both topical steroids dupilumab (a systemic IL-4R α inhibitor), there remains lack guidelines for treatment elderly Herein, we describe the five patients (≥ 65-years-old) with upadacitinib, novel JAK-inhibitor rarely used elevated risk side...
<title>Abstract</title> Systemic sclerosis (SSc) is a rare, multisystem autoimmune connective tissue disease, with skewing of the T helper 1 (Th1) immune response associated progression. In contrast, atopic disorders are common chronic diseases Th2 axis implicated in pathogenesis. Previous research suggests that cytokines, namely IL-4 and IL-13, may play role inflammatory fibrotic phases SSc. A previous epidemiological study also showed an association between SSc dermatitis. Herein, we...
Systemic Janus kinase inhibitors (JAK-inhs) are a novel treatment option approved for use in several inflammatory conditions that span dermatology, rheumatology, and gastroenterology. Side effects associated with JAK-inhs the general patient population include infections, increased lipids, cytopenias, major adverse cardiovascular events, thromboembolic herpes, malignancies.1Klein B. Treudler R. Simon J.C. JAK-inhibitors dermatology – small molecules, big impact? Overview of mechanism action,...
Induced expression of sucrose synthase