A5101333640- Cancer-related Molecular Pathways
- Hedgehog Signaling Pathway Studies
- Ubiquitin and proteasome pathways
- Adipose Tissue and Metabolism
- Angiogenesis and VEGF in Cancer
- Immune Cell Function and Interaction
- Metabolism, Diabetes, and Cancer
- Industrial Technology and Control Systems
- CAR-T cell therapy research
- Pancreatic function and diabetes
- Hematopoietic Stem Cell Transplantation
- Biochemical effects in animals
- Diabetes Treatment and Management
- Lipid metabolism and disorders
- Liver physiology and pathology
- Belt Conveyor Systems Engineering
- Tissue Engineering and Regenerative Medicine
- Wnt/β-catenin signaling in development and cancer
- Biological Stains and Phytochemicals
- Control Systems in Engineering
- TGF-β signaling in diseases
- Traditional Chinese Medicine Analysis
- Diet, Metabolism, and Disease
- Muscle Physiology and Disorders
- Pulmonary Hypertension Research and Treatments
Fujian Medical University
2024
Hebei University of Engineering
2023-2024
Affiliated Hospital of Hebei University
2023-2024
Army Medical University
2024
Southwest Hospital
2024
China Coal Technology and Engineering Group Corp (China)
2023
Xiangnan University
2023
Chinese General Hospital College of Nursing and Liberal Arts
2017-2018
Abstract Background Bone morphogenetic protein 9 (BMP9) is a hepatokine that plays pivotal role in the progression of liver diseases. Moreover, an increasing number studies have shown BMP9 associated with hepatopulmonary syndrome (HPS), but its HPS unclear. Here, we evaluated influence CBDL on expression and investigated potential mechanisms signalling HPS. Methods We profiled circulating levels common bile duct ligation‐induced rat model, then effects serum pulmonary vascular endothelial...
Diabetes mellitus (DM), becomes a main public health issue worldwide due to the rapid increase in DM patient numbers. The dysfunction of endothelial progenitor cells (EPCs) patients plays critical role repair and progression DM-related vascular complications. Loxenatide is an glucagon-like peptide 1 receptor agonist, which used control glycemic type 2 diabetes patients. However, EPCs remains be investigated. were isolated, characterized, treated with Loxenatide, high-glucose, or 3-TYP....
Mantle cell lymphoma (MCL) is a rare and aggressive form of non-Hodgkin lymphoma. Challenges in its treatment include relapse, drug resistance, short survival period. The Hedgehog/GLI1 (Hh/GLI1) Wnt/β-catenin pathways are crucial cancer proliferation, survival, making them significant targets for anticancer research. This study aimed to assess the effectiveness combining inhibitors both against MCL investigate underlying molecular mechanisms. co-expression key proteins from Hh/GLI1 was...
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are effective hypoglycemic agents for type 2 diabetes mellitus (T2DM). It was reported that T2DM implicated in pancreatic β-cell senescence. Whether loxenatide regulates cellular senescence of β-cells is to be investigated. Our results revealed high glucose (HG)-induced and elevated expression SASP factors inhibited cell proliferation stimulated DNA damage, which were reversed by treatment. In addition, HG induction resulted promoted...
In order to solve the problems of winches in fully mechanized coal mining face used do roadway supports withdrawal work, such as difficult operation, tedious positioning, inefficiency, frequent pull-off and rope breakage so on. A new dual-speed multi-purpose winch with variable frequency speed control self-supporting positioning system is proposed this paper. Firstly, The shape performance boundary parameters are obtained by analyzing investigating existing requirements new. Secondly,...