A5044297043- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Cancer Genomics and Diagnostics
- RNA modifications and cancer
- T-cell and Retrovirus Studies
Kilimanjaro Christian Medical Centre
2022-2025
Epstein-Barr virus (EBV)-positive Burkitt lymphoma (BL) affects children in sub-Saharan Africa, but diagnosis via tissue biopsy is challenging. We explored a liquid approach using targeted next-generation sequencing to detect the The panel included targets for characteristic detected three of four This analysis demonstrates potential improve BL settings with limited pathology resources. Validation our larger data set needed.
Determining the cost of diagnosis Burkitt lymphoma by DNA sequencing from a blood sample, compared with current histopathology. Estimating future costs at increased scale and exploring effect positivity rate on per-case cost. We conducted microcosting both diagnostics. Resource use information was derived standard operating procedures interviews staff. Unit data were salary scales, purchase records, publicly available prices. Costs collected during 2021 2022, in currency purchase, converted...
Background: NLPHL is a rare subtype of HL and constitutes to approximately 5% all HL, hence less than 0.5% lymphomas [1,2]. For Sub-Saharan Africa, publications about are literally non existing. Due the rarity NLPHL, clinical trial data limited, but generally associated with good prognosis [3,4]. CD20 positivity, use CD20-antibodies recommended contributes treatment outcome according from high income countries. As patient’s characteristics African NHLP patients have not been reported as...