- Caveolin-1 and cellular processes
- Insect symbiosis and bacterial influences
- Science, Research, and Medicine
- Glycosylation and Glycoproteins Research
- interferon and immune responses
- Signaling Pathways in Disease
- Galectins and Cancer Biology
- Animal Virus Infections Studies
- RNA Research and Splicing
- Insect Resistance and Genetics
- Testicular diseases and treatments
- Invertebrate Immune Response Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Cell Adhesion Molecules Research
- Erythrocyte Function and Pathophysiology
Institut Curie
2018-2024
Inserm
2018-2024
Université Paris Sciences et Lettres
2018-2024
Centre National de la Recherche Scientifique
2024
Université Paris Cité
2023
NeuroDiderot
2023
Délégation Paris 7
2023
Hospital Fatuma Bourguiba Monastir
2021
University of Monastir
2021
Birla Institute of Technology and Science, Pilani
2019
Caveolae are small invaginated pits that function as dynamic mechanosensors to buffer tension variations at the plasma membrane. Here we show under mechanical stress, EHD2 ATPase is rapidly released from caveolae, SUMOylated, and translocated nucleus, where it regulates transcription of several genes including those coding for caveolae constituents. We also found required maintain reservoir membrane during induced by stress. Metal-replica electron microscopy breast cancer cells lacking...
Abstract SARS-CoV-2 interacts with cellular cholesterol during many stages of its replication cycle. Pantethine was reported to reduce total levels and fatty acid synthesis potentially alter different processes that might be involved in the Here, we explored potential antiviral effects pantethine two vitro experimental models infection, Vero E6 cells Calu-3a cells. reduced infection by both preinfection postinfection treatment regimens. Accordingly, expression viral spike nucleocapsid...
Essentially all plasma membrane proteins are glycosylated, and their activity is regulated by tuning cell surface dynamics. This achieved glycan-binding of the galectin family that either retain glycoproteins within lattices or drive endocytic uptake via clathrin-independent glycolipid-lectin (GL-Lect) mechanism. Here, we have used immunofluorescence-based assays to analyze how lattice GL-Lect mechanisms affect internalization adhesion migration glycoprotein α5β1 integrin. In retinal pigment...
This paper report presents the interdisciplinary science showcased at Young Scientists Retreat 2019. The retreat was jointly organized by young researchers from Instituto Gulbenkian de Ciência (Portugal) and Institut Curie (France) took place in Pedrógão Pequeno, a small village central region of Portugal September Three keynote speakers were invited to present their work, Alfonso Martinez-Arias, Biola Javierre Martínez, Sara Magalhães....