Satish Kailasam Mani

ORCID: 0009-0006-9998-0863
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Caveolin-1 and cellular processes
  • Insect symbiosis and bacterial influences
  • Science, Research, and Medicine
  • Glycosylation and Glycoproteins Research
  • interferon and immune responses
  • Signaling Pathways in Disease
  • Galectins and Cancer Biology
  • Animal Virus Infections Studies
  • RNA Research and Splicing
  • Insect Resistance and Genetics
  • Testicular diseases and treatments
  • Invertebrate Immune Response Mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • Cell Adhesion Molecules Research
  • Erythrocyte Function and Pathophysiology

Institut Curie
2018-2024

Inserm
2018-2024

Université Paris Sciences et Lettres
2018-2024

Centre National de la Recherche Scientifique
2024

Université Paris Cité
2023

NeuroDiderot
2023

Délégation Paris 7
2023

Hospital Fatuma Bourguiba Monastir
2021

University of Monastir
2021

Birla Institute of Technology and Science, Pilani
2019

Caveolae are small invaginated pits that function as dynamic mechanosensors to buffer tension variations at the plasma membrane. Here we show under mechanical stress, EHD2 ATPase is rapidly released from caveolae, SUMOylated, and translocated nucleus, where it regulates transcription of several genes including those coding for caveolae constituents. We also found required maintain reservoir membrane during induced by stress. Metal-replica electron microscopy breast cancer cells lacking...

10.1083/jcb.201801122 article EN cc-by-nc-sa The Journal of Cell Biology 2018-10-22

Abstract SARS-CoV-2 interacts with cellular cholesterol during many stages of its replication cycle. Pantethine was reported to reduce total levels and fatty acid synthesis potentially alter different processes that might be involved in the Here, we explored potential antiviral effects pantethine two vitro experimental models infection, Vero E6 cells Calu-3a cells. reduced infection by both preinfection postinfection treatment regimens. Accordingly, expression viral spike nucleocapsid...

10.1038/s41598-023-29245-0 article EN cc-by Scientific Reports 2023-02-08

Essentially all plasma membrane proteins are glycosylated, and their activity is regulated by tuning cell surface dynamics. This achieved glycan-binding of the galectin family that either retain glycoproteins within lattices or drive endocytic uptake via clathrin-independent glycolipid-lectin (GL-Lect) mechanism. Here, we have used immunofluorescence-based assays to analyze how lattice GL-Lect mechanisms affect internalization adhesion migration glycoprotein α5β1 integrin. In retinal pigment...

10.3390/biom14091169 article EN cc-by Biomolecules 2024-09-18

This paper report presents the interdisciplinary science showcased at Young Scientists Retreat 2019. The retreat was jointly organized by young researchers from Instituto Gulbenkian de Ciência (Portugal) and Institut Curie (France) took place in Pedrógão Pequeno, a small village central region of Portugal September Three keynote speakers were invited to present their work, Alfonso Martinez-Arias, Biola Javierre Martínez, Sara Magalhães....

10.20944/preprints202001.0099.v1 preprint EN 2020-01-11
Coming Soon ...