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Valeria Olaya-Valdiviezo

ORCID: 0009-0007-0126-7187
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About
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A5024445663
Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Autoimmune and Inflammatory Disorders Research
  • Toxin Mechanisms and Immunotoxins

Universidad de Guadalajara
 2023

 IL-21 (rs2055979 and rs2221903)/IL-21R (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients
OPENALEX - Publications 
Noemi Magdalena Carreño-Saavedra Itzel Viridiana Reyes‐Pérez Andrea Carolina Machado-Sulbarán Gloria Martínez-Bonilla Maria Guadalupe Ramírez‐Dueñas and 5 more José Francisco Muñoz‐Valle Valeria Olaya-Valdiviezo Trinidad García‐Iglesias Erika Aurora Martínez-García Pedro Ernesto Sánchez‐Hernández

Rheumatoid Arthritis (RA) is characterized by joint destruction, chronic inflammation, and autoantibody production. IL-21/IL-21R plays an essential role in the immunopathology of RA. Elevated IL-21 serum levels have been associated with RA disease activity. Here, we evaluated association polymorphisms The study included 275 patients 280 Control subjects (CSs). Single nucleotide (rs2055979 rs2221903) IL-21R (rs3093301) were genotyped using PCR-RFLP. Clinical activity was DAS28-ESR; anti-CCP...

10.3390/genes14040878 article EN Genes 2023-04-07
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