A5077886639- Non-Invasive Vital Sign Monitoring
- Hemodynamic Monitoring and Therapy
- Heart Rate Variability and Autonomic Control
- Pulmonary Hypertension Research and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Climate Change and Health Impacts
- Thermoregulation and physiological responses
Washington University in St. Louis
2023-2024
Postpartum hemorrhage (PPH) is the leading and most preventable cause of maternal mortality, particularly in low-resource settings. PPH currently diagnosed through visual estimation blood loss or monitoring vital signs. Visual assessment routinely underestimates beyond point pharmaceutical intervention. Quantitative hemorrhage-induced compensatory processes, such as constriction peripheral vessels, may provide an early alert for PPH. To this end, we developed a low-cost, wearable optical...
To combat the unmet need of early detection and monitoring postpartum hemorrhage (PPH), leading cause maternal death, a wearable short-wave infrared (SWIR) photoplethysmography (PPG) sensor was developed for real-time hemodilution, compensatory response to PPH. The device uses wavelengths at 900 1300nm, ideal hemoglobin water contributions in blood, respectively. These minimally absorb melanin, which has been shown bias PPG results pulse oximetry. High signal-to-noise signals have acquired...
Pulse oximeters play a critical role in health monitoring. ox measurements have statistical bias that is function of race, which results higher rates occult hypoxemia, i.e., missed detection dangerously low oxygenation, patients color. This paper further characterizes the distribution pulse measurements, showing they also variance for racialized as Black, compared to those white. By analyzing performance hypoxemia detector, we show no single race-based correction factor will provide equal by...
Postpartum hemorrhage (PPH) is both the leading and most preventable cause of maternal mortality. PPH currently diagnosed through visual estimation blood loss or vital sign analysis shock index (ratio heart rate to systolic pressure). Visual assessment underestimates loss, particularly in setting internal bleeding, compensatory mechanisms stabilize hemodynamics until massive, beyond point pharmaceutical intervention. Quantitative monitoring hemorrhage-induced processes, such as constriction...