A5101632366- Gene Regulatory Network Analysis
- CRISPR and Genetic Engineering
- Remote-Sensing Image Classification
- Microbial Metabolic Engineering and Bioproduction
- Mitochondrial Function and Pathology
- Rangeland Management and Livestock Ecology
- 3D Printing in Biomedical Research
- Agriculture, Land Use, Rural Development
- Fatigue and fracture mechanics
- Alzheimer's disease research and treatments
- Anesthesia and Neurotoxicity Research
- MicroRNA in disease regulation
- Fire effects on concrete materials
- Digital Media and Visual Art
- Innovation and Socioeconomic Development
- Wireless Signal Modulation Classification
- Perovskite Materials and Applications
- Mechanical and Thermal Properties Analysis
- Metal Forming Simulation Techniques
- Geoscience and Mining Technology
- Semiconductor Quantum Structures and Devices
- Nuclear Receptors and Signaling
- Land Rights and Reforms
- Vehicular Ad Hoc Networks (VANETs)
- Machine Learning in Materials Science
Anhui University of Technology
2022-2025
Hubei University
2023-2024
Harbin Engineering University
2023-2024
Huazhong University of Science and Technology
2023
South China Normal University
2022
University of Chinese Academy of Sciences
2017-2022
Microbiology Institute of Shaanxi
2020-2022
Institute of Microbiology
2017-2022
State Key Laboratory of Microbial Resources
2020-2022
Chinese Academy of Sciences
2017-2022
Abstract Rational engineering of biological systems is often complicated by the complex but unwanted interactions between cellular components at multiple levels. Here we address this issue level prokaryotic transcription insulating minimal promoters and operators to prevent their interaction enable biophysical modeling synthetic without free parameters. This approach allows genetic circuit design with extraordinary precision diversity, consequently simplifies design-build-test-learn cycle a...
Abstract New materials for electrochemical energy storage and conversion are the key to electrification sustainable development of our modern societies. Molecular modelling based on principles quantum mechanics statistical as well empowered by machine learning techniques can help us understand, control design at atomistic precision. Therefore, this roadmap, which is a collection authoritative opinions, serves gateway both experts beginners have quick overview current status corresponding...
Acoustic nonlinearity derived from microstructural evolution of metallic materials during plastic deformation has been found to be a promising nondestructive technique identify early stage damage in structural components. In the current investigation, propagation longitudinal ultrasonic waves plastically deformed 35CrMoA steel plates was simulated using finite element (FE) methods based on theory dislocation-induced acoustic establish relationship between parameters and strain. Experiments...
Mitigating unintended interferences between circuits and host cells is key to realize applications of synthetic regulatory systems both for bacteria mammalian cells. Here, we demonstrated that growth burden circuit dysregulation occurred in a concentration-dependent manner specific transcription factors (CymR*/CymR) E.coli, direct negative feedback modules were able control the concentration CymR*/CymR, mitigate burden, restore functions. A quantitative design scheme was developed embedded...
Journal Article Engineering of a genetic circuit with regulatable multistability Get access Tingting Li, Li Centre for Quantitative Biology and Peking-Tsinghua Joint Life Sciences, Peking University, Beijing 100871, China https://orcid.org/0000-0002-2303-6394 Search other works by this author on: Oxford Academic Google Scholar Yiming Dong, Dong Xuanqi Zhang, Zhang Xiangyu Ji, Ji CAS Key Laboratory Microbial Physiological Metabolic Engineering, Institute Microbiology, Chinese Academy...
The Magnoliaceae shows strong phylogenetic niche conservatism, in which temporal petal closure has been extensively reported. However, it is yet elusive whether an idle floral character inherited from their ancestors or adaptive trait to habitats. Here, we monitored the process of and re-opening a thermogenic plant, Magnolia denudata (Magnoliaceae). Furthermore, artificially interrupted investigated its effects on development female male gametophytes. Intriguingly, found considerable...
Due to their spatial and spectral information, hyperspectral images are frequently used in various scientific industrial fields. Recent developments image classification have revolved around the use of convolutional neural networks transformers, which capable modeling local global data. However, most backbone existing methods based on 3-D convolution, has high complexity network structure. Moreover, information extracted through different modules, coupling relationship between two types is...
The selection of photoactive materials and the design device structures are critical to photoelectronic performance photodetectors. This study reports on a vertically structured photodetector with rapid, stable, efficient photoelectric across UV-visible broadband range based Si
Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia, and the is mediated expression of mitochondrial proteins. This study investigated involvement proteins hippocampal cell after transient ischemia-reperfusion injury aged rats using a comparative proteomics strategy. Our experimental results show that rat brain sensitive to ischemia led hippocampus changes memory cognition rats. Differential analysis suggested this phenomenon may be associated with energy...
Ambipolar FETs were designed and fabricated based on the Ph-BTBT-10/PMMA/ZnO structure by a solution process.
Background. Acute myocardial infarction (AMI) involves a series of complex cellular and molecular events, including circular RNAs (circRNAs), microRNAs (miRNAs) other noncoding RNAs. Objective. In this study, the regulation mechanism circEIF4G2 acting on miR-26a HUVECs (Human Umbilical Vein Endothelial Cells) proliferation, cell cycle angiogenesis ability was mainly explored in vascular endothelial growth factor induced (VEGF-induced) model. Methods. VEGF model constructed, expression...
Pipe to elbow welds are usually identified as the weakest parts in pipeline system of ultra-supercritical boilers due structural induced stress arising from internal steam pressure, and constraint supports hangers. The finite element (FE) method has been applied investigate effect on creep evolution pipe welds. results show that compressive axial can significantly increase strain near pipe’s outer surface. In contrast, inner surface is clearly accelerated by tensile stress. Compared with...