A5084693964- Pneumonia and Respiratory Infections
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Bacterial Infections and Vaccines
- Diagnosis and treatment of tuberculosis
- Reproductive tract infections research
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Pneumocystis jirovecii pneumonia detection and treatment
- Actinomycetales infections and treatment
- Antimicrobial Resistance in Staphylococcus
- Infections and bacterial resistance
- Respiratory viral infections research
- Rabies epidemiology and control
- Plant Pathogenic Bacteria Studies
- Leech Biology and Applications
- Antibiotic Resistance in Bacteria
- Urinary Tract Infections Management
- Vitamin C and Antioxidants Research
- Diphtheria, Corynebacterium, and Tetanus
- Bacterial biofilms and quorum sensing
- Cervical Cancer and HPV Research
- Ocular Infections and Treatments
- Infective Endocarditis Diagnosis and Management
Centre Hospitalier Universitaire Amiens-Picardie
2010-2024
Centre Hospitalier Régional et Universitaire de Nancy
2023-2024
IE University
2021
University Medical Center
2021
Laboratoire de Glycochimie, des Antimicrobiens et des Agroressources
2014-2015
Centre Hospitalier Universitaire de Limoges
2015
Hôpital Universitaire Dupuytren
2014
Ecologie Microbienne Lyon
2009
Université Claude Bernard Lyon 1
2009
Centre National de la Recherche Scientifique
2009
An increasing burden of evidence is pointing toward pesticides as risk factors for chronic disorders such obesity and type 2 diabetes, leading to metabolic syndrome. Our objective was assess the impact chlorpyrifos (CPF) on bacteriologic markers. Female rats were exposed before during gestation lactation CPF (1 mg/kg/day). Outcomes weight, glucose lipid profiles, well disturbances in selected gut bacterial levels, measured both dams (at end period) their female offspring at early adulthood...
Sixty-two clinical isolates of Enterobacter aerogenes resistant to expanded-spectrum cephalosporins were collected between July 2003 and May 2005. Among these isolates, 23 (37.1%) imipenem (IPM) susceptible, 39 (62.9%) IPM insusceptible, which 89.7% (35/39) 10.3% (4/39) intermediate. Isolate genotypes compared by pulsed-field gel electrophoresis. Of 62 48 belonged epidemic pulsotype A (77.4%). This included 37.5% 58.4% beta-lactam phenotypes b a, respectively. Nine (14.5%) E, 22.3% 77.7% The...
The 23 French Regional Pneumococcal Observatories (ORPs) analyzed antibiotic resistance and serotypes of Streptococcus pneumoniae strains isolated from invasive infections in France over a 12-year period.Between 2009 2021, the ORPs 19,319 strains, including 1,965 children 17,354 adults. Strains were assessed for their to penicillin G, amoxicillin cefotaxime. Serotypes identified collaboration with National Reference Centre.During this period, number collected yearly decreased significantly....
Antimicrobial resistance of Streptococcus pneumoniae in France is closely monitored by the pneumococcus surveillance network, founded 1995, which collects data from regional observatories (Observatoire Régionaux du Pneumocoque [ORP]). In 2007, 23 ORPs analyzed antibiotic susceptibility 5,302 isolates S. recovered cerebrospinal fluid, blood, middle ear and pleural as well adult respiratory samples. The study showed that 38.2% strains were nonsusceptible to penicillin, 19.3% amoxicillin, 10.5%...
Pasteurella spp. can lead to fatal infections in humans.To assess prognostic factors of invasive pasteurellosis.We conducted a single retrospective cohort study local versus from January 1, 2005, December 31, 2018, the Amiens-Picardie University Hospital, France.Forty-five (20.9%) pasteurellosis and 22 (10.2%) complicated were reported among total 215 infections. The mortality rate was 22.2% (10/ 45) whereas no death recorded group. Non-drug-induced prothrombin time test <70% standard...
ABSTRACT We describe here the first case of Nocardia nova spondylodiscitis accompanied by a psoas abscess due to spreading from pulmonary nocardiosis. was cultured all affected sites. After 1 year an appropriate antimicrobial therapy and surgical drainage that required, patient's clinical condition had improved.
ABSTRACT Teicoplanin is a key drug for the treatment of multiresistant staphylococcal bone and joint infections (BJI), yet can only be administered via parenteral route. The objective this study was to evaluate safety tolerability subcutaneous (s.c.) teicoplanin that indication over 42 days. Thirty patients with Gram-positive cocci BJI were included. Once target 25 40 mg/liter trough serum concentration achieved, switched from an intravenous s.c. No discontinuation related injection site...
ABSTRACT In a series of 82 Staphylococcus strains isolated from culture, 100% were identified as aureus by matrix-assisted laser desorption ionization–time flight mass spectrometry (MALDI-TOF MS); 99.9% (77/82) them resistant to benzylpenicillin, oxacillin, and cefoxitin, 6.1% (5/82) susceptible methicillin. Xpert MRSA/SA assay results concordant with the phenotypic in 76.8% (63/82) cases discordant 23.2% (19/82) cases. The ELITe MGB kit When comparing results, 78% (64/82) concordant, while...
Human are confronted on a daily basis with contaminant pesticide residues in food, water and other components of the environment. Although digestive system is first organ to come into contact food contaminants, very few data available impact low-dose exposure during utero postnatal periods intestinal bacterial translocation (BT). Previous studies have revealed that chlorpyrifos (CPF) associated dysbiosis contamination sterile organs. Here, molecular typing was used investigate rats exposed...
Nine percent of all cases tuberculosis are bone and joint (BJTB). BJTB occurs in two main forms: spinal (STB) extraspinal (ESTB). The aim this study was to compare STB with ESTB terms diagnosis, treatment outcomes.We collected demographic, clinical, microbiological, duration outcome data for patients a retrospective multicentre over 17-year period.Of the 116 included study, 69 (59.5%) had 47 (40.5%) ESTB. median age higher group. There were significantly more foreign-born time diagnosis...
ObjectivesNontuberculous mycobacteria (NTM) bone and joint infections (BJIs) are uncommon. We evaluated the characteristics of BJIs identified differences according to immune status.MethodsWe performed a multicenter retrospective study in France involving patients with documented NTM BJI over 9-year period. collected clinical microbiological characteristics, management, outcomes patients.ResultsNinety-five were included, whom 50.5% (48/95) immunosuppressed. Tenosynovitis was more frequent...
Purpose: To determine the prevalence of Chlamydia trachomatis infection in a high-risk population by direct and indirect methods to evaluate diagnosis secretory immunoglobulin A (sIgA). Patients Methods: Urethral or endocervical specimens from 78 patients (48 females 30 males) were examined cell culture, fluorescence assay, PCR Cobas Amplicor (Roche Molecular Diagnostics), sIgA was detected recombinant lipopolysaccharide (LPS)-enzyme-linked immunoassay (rELISA). Serum each patient also...
Clostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues. infection typically occurs after penetrating injury with soil-contaminated foreign bodies.Here, we describe the case a 17-year-old male who sustained metallic intraocular body and rapidly developed severe C. panophthalmitis orbital cellulitis. He was managed by systemic intravitreal antibiotics, resulting preservation globe, but poor visual outcome.Clostridial endophthalmitis...
ABSTRACT We describe here the first case of Nocardia nova spondylodiscitis accompanied by a psoas abscess due to spreading from pulmonary nocardiosis. was cultured all affected sites. After 1 year an appropriate antimicrobial therapy and surgical drainage that required, patient's clinical condition had improved.
Introduction: Kocuria spp. rarely cause infectious disease but can be opportunistic pathogens in immunocompromised patients. The numbers of documented infections are low rising. Case presentation: A 74‐year‐old woman presented with acute, painful swelling the medial canthus left eye. skin surface was red and acutely to touch. Because several clinical relapses despite antibiotic treatment, surgical dacryocystorhinostomy marsupialization lacrimal sac into nasal cavity performed. Lacrimal...
Achromobacter spp. are nonfermenting Gram-negative bacilli mainly studied among cystic fibrosis (CF) patients. The identification of the 19 species within genus is time-consuming (nrdA-sequencing), thus data concerning distribution limited to specific studies. Recently, we built a database using MALDI-TOF mass spectrometry (MS) (Bruker) that allows rapid and accurate detection multiresistant epidemic clones: A. xylosoxidans ST137 spreading CF patients in various French Belgium centers,...
Eighty-five atypical isolates of Staphylococcus aureus divided into 73 aminoglycoside-susceptible methicillinresistant (AS-MRSA) and 12 kanamycin-tobramycin-resistant methicillin-susceptible (KTR-MSSA) were phenotypically genotypically examined for methicillin resistance. Among these tests, the diffusion method using oxacillin cefoxitin disks on Mueller–Hinton agar with without NaCl, incubation at 35°C or 30°C 24 48 hr, respectively, determination MICs by E-test performed. We also presence...