A5101927031- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Hormonal Regulation and Hypertension
- Infective Endocarditis Diagnosis and Management
- Connective tissue disorders research
- Coronary Artery Anomalies
- Streptococcal Infections and Treatments
- Vasculitis and related conditions
- Infectious Aortic and Vascular Conditions
- Esophageal and GI Pathology
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Vitamin K Research Studies
- Birth, Development, and Health
- Atherosclerosis and Cardiovascular Diseases
- Otitis Media and Relapsing Polychondritis
- Anesthesia and Neurotoxicity Research
- Genetic Neurodegenerative Diseases
- Advanced Glycation End Products research
- Ocular Diseases and Behçet’s Syndrome
- Mechanical Circulatory Support Devices
- Frailty in Older Adults
Nanjing Medical University
2025
Huaian First People’s Hospital
2025
Changhai Hospital
2010-2024
Second Military Medical University
2011-2024
Shanghai Second People's Hospital
2013
People's Liberation Army 411 Hospital
2010
In recent years, the incidence of oesophageal squamous cell carcinoma has been increasing, becoming a major focus public attention. Despite surgery being primary treatment method, long-term prognosis after is also significant importance. Therefore, this study aims to investigate impact dietary behaviour changes on patients with surgery. A retrospective cohort was adopted, involving who underwent at Department Thoracic Surgery, Affiliated Huaian No. 1 People's Hospital Nanjing Medical...
Systemic immune-inflammation index (SII) is a biomarker that reflect systemic inflammation. We aimed to assess the value of SII in prediction short-term outcomes acute type A aortic dissection (ATAD) patients undergoing surgery.All underwent surgery for ATAD at our institution from 2018 2020 (n = 324) were retrospectively reviewed and divided into low (<1582.6 × 109 /L) high (≥1582.6 group according optimal cut-off values defined by receiver operating characteristic curve. Cox regression...
Many countries and regions have established multicenter registration studies to improve the outcomes of acute type A aortic dissection (ATAAD).
Abstract Background Postoperative hypoxemia in acute type A aortic dissection (AADA) is a common complication and associated with negative outcomes. This study aimed to analyze the efficacy of low-dose (5–10 ppm) inhaled nitric oxide (iNO) management after AADA surgery. Methods In this retrospective observational study, Medical records patients who underwent surgery at two institutions between January 2015 2018 were collected. Patients postoperative classified as iNO control groups. Clinical...
Knowledge about the risk factors of in-hospital mortality for acute type A aortic dissection (ATAAD) patients who received total arch procedure is limited. This study aims to investigate preoperative and intraoperative these patients.From May 2014 June 2018, 372 ATAAD in our institution. These were divided into survival death groups, patients` data retrospectively collected. Receiver operating characteristic curve analysis was adopted determine optimal cut-off value continuous variables....
Atrial fibrillation is associated with the activation of renin-angiotensin-aldosterone system in atria. It not clear whether expression mineralocorticoid receptor (MR) and aldosterone synthase CYPII B2 patients atrial altered. This study aimed to investigate mRNA MR CYPIIB2 reveal correlation between matrix remodelling fibrillation.Twenty-five rheumatic heart valve disease, 12 sinus rhythm 13 (> or = 6 months), underwent a replacement operation right left lateral wall tissue samples were...
Objective: There are debates regarding the optimal approach for AAAD involving aortic root.We described a modified reinforced root reconstruction treating root.Methods: A total of 161 patients with were treated by our from January 1998 to December 2008.Key features placement an autologous pericardial patch in false lumen, lining sinotubular junction lumen polyester vascular ring, and wrapping vessel Teflon strips.Outcome measures included post-operative mortality, survival, complications,...
Multiple of subsequent procedures may necessary in Marfan syndrome (MFS) patients after initial surgery. The aim this study was to investigate the full spectrum secondary distal vascular or valvular interventions encountered surgery.Retrospective analysis 201 consecutive MFS between January 2000 and March 2019 who underwent 274 aortic reinterventions 5 mitral valve replacements.Of enrolled (73 female, mean age 37.0±12.8 years), surgical indication for 93 root aneurysm, another 108...
Objective Though the prognostic value of model for end-stage liver disease (MELD) score in tricuspid surgery was confirmed, unstable international normalized ratio (INR) may affect evaluation effectiveness MELD isolated valve replacement (ITVR). The aim study to assess modified ITVR. Methods and Results A total 152 patients who underwent ITVR were evaluated. adverse outcome defined as in-hospital mortality after surgery. receiver operating characteristic (ROC) curve analysis demonstrated...
Thoracic aortic dissection (TAD) is a life-threatening vascular disease manifested as intramural bleeding in the medial layers of thoracic aorta. The key histopathologic feature TAD degeneration, characterized by depletion smooth muscle cells (VSMCs) and degradation extracellular matrix (ECM). MicroRNA, essential epigenetic regulators, can inhibit protein expression target genes without modifying sequences. This study aimed to elucidate role underlying mechanism miR-20a, member miR-17-92...
Background : The treatment strategy of early nutritional support after cardiac surgery has gradually been adopted. However, there are no scientific guidelines for the timing and specific programs support. Methods: A retrospective, single-center analysis (2021-2023) was carried out including elderly patients who were admitted valvular heart disease received open-heart valve replacement surgery. We designated started optimized as enteral TN (EN) group those traditional (TN) group. immune...
: Pathological cardiac hypertrophy, a condition that contributes to heart failure, is characterized by its intricate pathogenesis. The meticulous regulation of protein function, localization, and degradation crucial role played deubiquitinating enzymes in pathophysiology. This study clarifies the participation molecular mechanism OTUD1 (OTU Deubiquitinase 1) pathological hypertrophy.