Nicole Porio
A5092048094- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- COVID-19 Impact on Reproduction
- COVID-19 and healthcare impacts
- Kawasaki Disease and Coronary Complications
- Cardiovascular Issues in Pregnancy
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Diabetes and associated disorders
- Patient Safety and Medication Errors
- Chemotherapy-induced cardiotoxicity and mitigation
- Diagnosis and Treatment of Venous Diseases
- Blood groups and transfusion
- Acute Ischemic Stroke Management
- Acute Myocardial Infarction Research
- Healthcare Systems and Public Health
- Sepsis Diagnosis and Treatment
Harvard University
2023-2025
Brigham and Women's Hospital
2023-2025
Coronavirus disease 2019 (COVID-19) is associated with excess risk of cardiovascular and thrombotic events in the early post-infection period during convalescence. Despite progress our understanding complications, uncertainty persists respect to more recent event rates, temporal trends, association between vaccination status outcomes, findings within vulnerable subgroups such as older adults (aged 65 years or older), those undergoing hemodialysis. Sex-informed findings, including results...
Essentials•Randomized trials suggest that direct oral anticoagulants (DOACs) may not be as safe or effective for mangement of venous thromboembolism (VTE) in certain situations.•We review scenarios where DOACs are and effective, they have reduced safety efficacy, when their and/or efficacy uncertain.•DOACs advised VTE antiphospholipid syndrome luminal cancers.•The remain uncertain some conditions.AbstractDirect become the preferred option treatment due to favorable profile compared with...
IntroductionPregnancy may contribute to an excess risk of thrombotic or cardiovascular events. COVID-19 increases the these events, although is relatively limited among outpatients. We sought determine whether outpatient pregnant women with are at a high for events.Materials & methodsWe analyzed outpatients from multicenter CORONA-VTE-Network registry. The main study outcomes were composite adjudicated venous arterial and Events assessed 90 days after diagnosis reported non-pregnant ≤45...
Introduction: Patients with COVID-19 are at an increased risk of cardiovascular complications. Studies indicating association between ABO blood groups and outcomes were limited by small sample size or use administrative claims data uncertain validity. Aim: To study the non-O group among patients in a large cohort adjudicated events. Methods: We examined from CORONA-VTE Network registry confirmed data. The main outcome was major events including venous arterial thrombosis, heart failure,...
Background: Active cancer and COVID-19 are each independently associated with excess risk of thrombotic cardiovascular outcomes. Data limited regarding the these outcomes in patients both active COVID-19. Aim: To examine association between among Methods: from confirmed multicenter CORONA-VTE Network registry were used. was defined as having a malignancy diagnosis within past year or receiving related treatment. Outcomes adjudicated included (1) composite venous arterial thromboembolism (2)...
Background: COVID-19 is a multiorgan disease characterized by prothrombotic state and increased risk of venous thromboembolism (VTE), especially in hospitalized patients. Although prior studies have attempted to identify predictors VTE, restricted sample size use administrative claims data limited such analyses. We conducted multivariable analysis VTE patients with multicenter patient-level registry. Methods: utilized from the CORONA-VTE Network, US registry 10,420 adult (≥18 years)...
Background: Coronavirus disease 2019 (COVID-19) is associated with excess risk of cardiovascular events. Despite the progress in our understanding complications, uncertainty persists respect to contemporary event rates, and association between use vaccines outcomes, changes incidence rates over time. Methods: Adult patients polymerase chain reaction-confirmed COVID-19 who received care at Mass General-Brigham health system, Beth Israel Deaconess Medical Center, Anne Arundel University...
Background: Venous thromboembolism (VTE) and arterial thrombosis are among serious complications of COVID-19 in the early post-infection period. Data less consistent about subsequent risk during convalescence, association between vaccination status COVID-19-assocaited thrombosis, or how event rates may have changed over time. Methods: In this multicenter study, adult patients who received inpatient outpatient care for confirmed at Mass General-Brigham health system, Beth Israel Deaconess...
Introduction: Perceived high bleeding risk is the primary reason for withholding anticoagulation (AC) in patients with atrial fibrillation (AF). We performed AF-ALERT 2, a randomized controlled trial (RCT) of alert-based computerized decision support (CDS), to increase AC prescription high-risk outpatients AF. Method: analyzed 397 alert group this determine clinical characteristics and outcomes patients. 77 perceived as having too were compared 320 low risk. Results: was main providers...
Abstract Background Coronavirus disease 2019 (COVID-19) is associated with excess risk of cardiovascular events in the early post-infection period and during convalescence. Despite progress our understanding complications, uncertainty persists respect to contemporary event rates particularly given change viral variants COVID-19 therapies, as well availability vaccines later months pandemic. Purpose To report complications COVID-19, assess results by vaccination status from a large...