Aryl ketones were synthesized via Pd-catalyzed decarboxylative coupling between O-methyl oximes and phenylglyoxylic acids using (NH(4))(2)S(2)O(8) as the oxidant.

Copper-mediated direct ortho C-H bond sulfonylation of benzoic acid derivatives with sodium sulfinates was achieved by employing an 8-aminoquinoline moiety as the bidentate directing group. Various aryl sulfones were synthesized in good yields excellent regioselectivity.

Abstract Efficient synthesis of trifluoromethyl and difluoromethyl‐substituted oxindoles was achieved by reacting Langlois reagent or Baran with N ‐arylacrylamides. However, the reaction aryl sulfinic acid sodium salts ‐arylacrylamides did not give desulfinative products, instead, sulfonated products were produced.

An efficient and stereoselective synthesis of vinylphosphonates phosphine oxides was developed starting from styrenes using AgNO₃as the catalyst K₂S₂O₈as oxidant. Various vinyl-phosphonates were synthesized in good yields with excellent regioselectivity.

Abstract A copper‐mediated, chelation‐assisted ortho CH bond nitration of benzoic acid derivatives using sodium nitrite as the source nitro group has been achieved with aid an 8‐aminoquinoline directing group. Selective mono‐ or dinitration can be by simply changing reaction conditions. The method shows excellent functional tolerance and provides a novel straightforward route for preparation ‐nitrated acids. magnified image

Huizhou villages are representatives of traditional and have a high historical, cultural, tourism value. In view the problems low commercial efficiency due to small scale space imperfect layout in Longchuan Village, Jixi County, Xuancheng City, Anhui Province, this research explores spatial advantages Village’s through an analysis street lane syntax resistance model. The on streets mainly focuses accessibility, line-of-sight integration, comprehensibility streets. model studies attraction...

Nontransition metal-catalyzed synthesis of 2-aryl benzothiazoles was achieved through K(2)S(2)O(8)-mediated oxidative condensation with aryl aldehydes. The same transformation can also be effected when the aldehydes were replaced phenylglyoxylic acids.

A highly mono-selective <italic>ortho</italic>-methylthiolation of benzamides was achieved <italic>via</italic> Co-catalyzed coupling with DMSO.

A novel cobalt-promoted arylation of aryl C–H bonds with arylboronic acids has been realized by using 8-aminoquinoline as the directing group. notable feature this newly developed protocol is that acrylamides, which cannot be arylated copper salts promoter, can also efficiently arylated.

The effect of buoyancy on fluid flows is a significant consideration in problems relating to energy, the environment, and health. Here, we examine what term “multi-buoyancy effect” (MBE), or “fluid-bunching effect,” which combination Archimedes number (Ar)-related resulting from temperature difference between flow ambient Gc (Gc)-related upper lower boundaries domain. A new semi-analytical mathematical model jet trajectory put forward by rational reconstruction. This reveals physical...

The physical and mechanical properties of recycled coarse aggregate (RCA) are worse than those natural (NCA), the overall performance concrete prepared from RCA is that concrete. Treatment by CO2-accelerated carbonation effectively improves macroscopic RCA. degree influence raw material factors, i.e., original strength (OCS) initial moisture content (IMC) RCA, on RCAs very complex. Herein, an accelerated experiment for with different factors as variables was carried out to explore...

Axon-wrapping myelin sheath is essential for the proper functioning of central nervous system (CNS). Defects in myelination occur various neurodevelopmental disorders. Human deficiency solute carrier 44A1 (SLC44A1) causes a new type childhood-onset neurodegeneration with leukoencephalopathy. Currently, there no effective treatment this devastating disease, and little known about its pathological mechanisms. In study we identified that SLC44A1 enriched oligodendrocytes required development...

We have discovered that phenyl tosylates can be used to arylate pyridines at the C3-position using a Pd(OAc)2–1,10-phenanthroline catalyst system. also reaction of 4-methylpyridine with naphthyl occurred on methyl group instead C3-position.

Abstract The copper‐mediated direct ortho CH bond arylation of benzamide derivatives with arylboronic acids was achieved by employing an 8‐aminoquinoline moiety as the bidentate directing group. Various biaryls were synthesized in good yields excellent regioselectivity. reaction shows functional group compatibility and proceeds a highly selective manner at ‐position benzamides. Deuterium‐labelling experiments indicated that cleavage involved rate‐determining step arylation. magnified image

A visible-light-induced and copper-promoted perfluoroalkylation of benzamides was successfully developed under the assistance an 8-aminoquinoline directing group. It provides a straightforward method for synthesis ortho-perfluoroalkyl-substituted benzoic acid derivatives. The reaction employs cheap organic dye eosin Y as photoredox catalyst is run irradiation 26 W fluorescent LED light bulb.

A novel HOTf-catalyzed oxyarylation of ynol ethers and thioethers has been realized with aryl sulfoxides as the oxyarylating reagents, providing α-arylated esters or thioesters in good to excellent yields. Notably, all atoms starting materials were incorporated product (100% atom economy) reaction proceeded under very mild conditions. It was found that can be ran air best yields are obtained solvent-free

A highly mono-selective ortho-trifluoromethylation of benzamides was achieved via Cu-promoted C-H activations. The reaction employs an 8-aminoquinoline group as the bidentate directing and Togni reagent II CF3 source. tolerated a wide variety functional groups various ortho-trifluoromethylated were efficiently synthesized in 36-82% yield.

A novel copper-catalyzed decarboxylative methylthiolation of arenecarboxylate salts has been realized using DMSO as the source. Various potassium aryl carboxylates underwent under air to furnish corresponding methyl thioethers in moderate excellent yields. The reaction tolerated a wide variety functional groups. Notably, synthesis ethylthioethers was also successfully achieved directly from diethyl sulfoxide similar conditions.

Abstract An efficient and mild protocol for the direct conversion of arene C−H bonds to C−NH 2 without need extra deprotection step has been established, best our knowledge, this is first time that synthesis primary anilines via nickel‐mediated C( sp )‐H activations reported. This approach utilizes 8‐aminoquinoline as directing group sodium azide, a cheap commercially available material, nitrogen source. In addition, reaction highly selective, affording mono ‐ ortho ‐aminated benzamides...