A5022124782- Mesenchymal stem cell research
- Knee injuries and reconstruction techniques
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Osteoarthritis Treatment and Mechanisms
- Innovative Microfluidic and Catalytic Techniques Innovation
- Phytochemical compounds biological activities
- 3D Printing in Biomedical Research
- Plant-derived Lignans Synthesis and Bioactivity
- Traditional and Medicinal Uses of Annonaceae
- Drug Solubulity and Delivery Systems
Guangdong Pharmaceutical University
2024-2025
Chinese PLA General Hospital
2018
Background: Powder-based 3D printing, an advanced additive manufacturing technique, can produce oral disintegrating tablets (ODTs) without disintegrants, creating larger-pored via layer-by-layer powder stacking for better water absorption than traditional tablets. Methods: This study focused on using powder-based printing to fabricate clozapine-based ODTs. Through central composite design (CCD), the formulation of ODTs was optimized rapid disintegration. Analytical techniques such as X-ray...
Arctigenin (ATG) is a broad-spectrum antitumor drug with an excellent inhibitory effect on malignant tumors such as breast cancer, glioblastoma, liver and colon cancer. However, the clinical application of ATG limited by its poor water solubility quick hydrolysis in liver, intestine, plasma, which might hinder application. Sialic acid (SA) recognizes selectin receptors overexpressed surface tumor-associated macrophages. In this study, SA was conjugated octadecylamine (ODA) to prepare SA-ODA,...