Abstract Five novel lanthanides(iii) complexes, [Lu(Me)(MBrQ)2NO3] (MeMBrQ-Lu), [Ho(MeO)(MBrQ)2NO3] (MeOMBrQ-Ho), [Ho(Me)(MBrQ)2NO3] (MeMBrQ-Ho), [La(Me)2(BrQ)2NO3] (MeBrQ-La) and [Sm(Me)(BrQ)2(CH3OH)NO3] (MeBrQ-Sm), have been synthesized, in which 2,2′-bipyridyl (4,4′-dimethyl-2,2′-bipyridyl (Me) 4,4′-dimethoxy-2,2′-bipyridine (MeO)) 5,7-dibromo-8-quinolinoline derivatives (5,7-dibromo-2-methyl-8-quinolinol (MBrQ-H) 5,7-dibromo-8-quinolinol (BrQ-H)) act as the chelating ligands. The vitro...

Three novel Ru(II) complexes, namely, (RuCl2[La][DMSO]2)·H2O (Ru1), (RuCl2[Lb][DMSO]2) (Ru2), and (RuCl2[Lc][DMSO]2) (Ru3), which respectively contain 3-(2'-benzimidazolyl)coumarin (La), 3-(2'-benzimidazolyl)-7-fluoro-coumarin (Lb), 3-(2'-benzimidazolyl)-7-methoxyl-coumarin (Lc), were first designed characterized. Ru2 showed potent antitumor activity against NCI-H460 cells (IC50 = 0.30 ± 0.02 μM) high selectivity between cancer normal HL-7702 cells. induced apoptosis via telomerase...

<bold>Pt2</bold> is a novel telomerase inhibitor binding to c-myc promoter elements, which arrests the cell cycle at G2/M phase and induces apoptosis causes mitochondrial dysfunction.

Electroacupuncture (EA), a treatment derived from traditional Chinese medicine, can effectively improve hyperandrogenism and insulin resistance in patients with polycystic ovary syndrome (PCOS), however, its underlying mechanisms remain obscure. This study aimed to investigate whether EA could mitigate PCOS-like symptoms rats by regulating autophagy. A rat model of was established subcutaneous injection dehydroepiandrosterone (DHEA), then at acupoints (ST29 SP6) carried out for 5 weeks. To...

A series of ruthenium complexes with dppz ligands were designed and synthesized as antimicrobial photosensitizers against S. aureus . These showed significant antibacterial ability both in vitro vivo

New-onset atrial fibrillation (NOAF) complicating acute myocardial infarction (AMI) has been associated with poor survival, but the clinical implication of NOAF on heart failure (HF) is still not well characterized. We aimed to investigate relationship between AMI and HF hospitalization.Adult patients identified in New-Onset Atrial Fibrillation Complicating Acute Myocardial Infarction Shanghai registry who, discharged alive, had complete echocardiography follow-up data from February 2014...

Shield tunnels built in soft soil are prone to settlement, which is often accompanied by convergence deformation, further resulting a series of damages the tunnel structure and compromise its safety service. This paper presents an engineering case on settlement development internal drilling grouting remediation section Shaoxing Metro Line 1, where inner diameter thickness linings increased be 5.9 m 400 mm simultaneously. The arises from comprehensive analysis several contributing factors,...

Background: Doxorubicin (DOX) is one of the widely used anti-cancer drugs, whereas it can induce irreversible cardiac injury in a dose-dependent manner which limits its utility clinic.Our study aimed to investigate relationship between miR-25 and DOX-induced underlying mechanism.Methods: Mice H9c2 cells were exposed DOX.The overexpressed or knockdown was achieved by mimic inhibitor efficiency transfection identified qRT-PCR Western blotting.Cell viability, apoptotic cell rate, levels...

Abstract Aims We aimed to investigate the prognostic impact of burden new-onset atrial fibrillation (NOAF) on long-term cardiovascular outcomes in patients with acute myocardial infarction (AMI). Methods and results This retrospective analysis consecutively included without a documented (AF) history who admitted for AMI at Shanghai Tenth People’s Hospital between February 2014 March 2018. Atrial was measured as percentage time spent AF, its optimal cut-off value 10.87% identified by X-tile...

To study the use of partial or total potassium bicarbonate (PBC) to replace sodium tripolyphosphate (STPP) on reduced-phosphate silver carp batters, all batters were composed surimi, pork back fat, ice water, spices, sugar, and chloride. Therein, sample T1 contained 4 g/kg STPP; T2 1 PBC, 3 T3 2 T4 T5 they produced using a bowl chopper. The changes in pH, whiteness, water- oil-holding capacity, gel rheological properties, as well protein conformation investigated. cooking yield, texture G′...

Abstract This prospective study evaluated the 95% effective dose ( ED 95 ) of nalbuphine in inhibiting body movement during outpatient‐induced abortion and its clinical efficacy versus equivalent sufentanil. The was divided into two parts. For first part, voluntary first‐trimester patients who needed induced abortions were recruited to measure using sequential method (the Dixon up‐and‐down method). In second this a double‐blind, randomized study. Sixty cases randomly groups (n = 30),...

Thioredoxins (Trxs) function within the antioxidant network through modulation of one or more redox reactions involved in oxidative-stress signaling. Given their regulating cellular redox, Trx proteins also fulfill key roles plant immune Here, TaTrxh1, encoding a subgroup h member family, was identified and cloned wheat (Triticum aestivum), which rapidly induced by Puccinia striiformis f. sp. tritici invasion salicylic acid (SA) treatment. Overexpression TaTrxh1 tobacco (Nicotiana...

Purpose: The prognostic impact of new-onset atrial fibrillation (NOAF) among different heart failure (HF) subtypes including HF with preserved (HFpEF, ejection fraction [EF] ≥ 50%), mid-range (HFmrEF, EF 40%∼ 49%), and reduced (HFrEF, < 40%) following acute myocardial infarction (AMI) remains unclear. We aimed to investigate the incidence implication post-MI NOAF across subtypes. Patients Methods: included 1413 patients (743 HFpEF, 342 HFmrEF 328 HFrEF) between February 2014 March 2018. was...

Emerging studies showed that lncRNA taurine upregulated 1 (TUG1) plays important roles in diverse biological processes. However, there is no previously published research reporting the regulatory role of lncRNAs progression adenomyosis. In present study, we found TUG1 human adenomyosis, and overexpression associated with transcription factor early growth response (EGR1). Functionally, knockdown inhibited adenomyotic epithelial cell migration invasion but not growth. The mechanistic...

Penicillium sp. 44M-3, previously isolated from soil samples in Sanmenxia City (Henan Province, China), was identified as aurantiogriseum Dierckx based on sequence analysis of ITS-rDNA, β-tubulin, and calmodulin. In co-culture assays against 14 pathogenic fungi, the inhibition ratios achieved by isolate 44M-3 ranged 42.90% to 66.0%. Optimising culture medium conditions maximise production inhibitory substances increased average activity filtrate 44.25% compared that original filtrate....

Background: New-onset atrial fibrillation (NOAF) is a common complication during acute myocardial infarction (AMI) and sometimes can be completely asymptomatic, but the clinical implications of these asymptomatic episodes require further characterization. The objective this study was to investigate short- long-term prognostic impact post-MI NOAF based on presence AF-related symptoms. Methods: New-Onset Atrial Fibrillation Complicating Acute Myocardial Infarction in ShangHai (NOAFCAMI-SH)...