A5101776530- Acupuncture Treatment Research Studies
- Mesenchymal stem cell research
- Wound Healing and Treatments
- Gastrointestinal motility and disorders
- Cellular Mechanics and Interactions
- Healthcare and Venom Research
- Ovarian function and disorders
- Adipose Tissue and Metabolism
- Diabetic Foot Ulcer Assessment and Management
- Nerve injury and regeneration
- Liver Disease Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Regulation of Appetite and Obesity
- Cell Adhesion Molecules Research
- Traditional Chinese Medicine Studies
- Endometrial and Cervical Cancer Treatments
- Pain Mechanisms and Treatments
- Hepatitis C virus research
- Pregnancy and Medication Impact
- High Altitude and Hypoxia
- Hippo pathway signaling and YAP/TAZ
- Infant Health and Development
- Dermatologic Treatments and Research
- Medical Research and Treatments
- Herbal Medicine Research Studies
Nanjing University of Chinese Medicine
2025
Nanjing Traditional Chinese Medicine Hospital
2025
Fudan University
2025
Jiangxi University of Traditional Chinese Medicine
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2025
East China University of Science and Technology
2019-2024
Shenzhen Maternity and Child Healthcare Hospital
2021-2024
Chinese People's Liberation Army
2024
Shanghai Skin Disease Hospital
2024
Hainan Branch of People's Liberation Army General Hospital
2024
ABSTRACT Objective This study aimed to analyze disease cost levels among colorectal cancer (CRC) patients, examining differences in costs between those with type 2 diabetes mellitus (T2DM) and without T2DM while considering various demographic characteristics. Methods The included respondents from patients diagnosed managed within the population‐based registry system of Shanghai Municipal Center for Disease Control Prevention 2020 2022. Diabetic cases were matched nondiabetic controls using...
To investigate the effect of stimulation human bronchial epithelial cells (HBECs) by arterial traffic ambient PM2.5 (TAPM2.5) and wood smoke (WSPM2.5) on expression long non-coding RNAs (lncRNAs) in order to find new therapeutic targets for treatment chronic obstructive pulmonary disease (COPD). HBECs were exposed TAPM2.5 WSPM2.5 at a series concentrations. The microarray analysis was used detect lncRNA mRNA profiles. Kyoto Encyclopedia Genes Genomes (KEGG) pathway gene ontology (GO)...
Electroacupuncture (EA), a treatment derived from traditional Chinese medicine, can effectively improve hyperandrogenism and insulin resistance in patients with polycystic ovary syndrome (PCOS), however, its underlying mechanisms remain obscure. This study aimed to investigate whether EA could mitigate PCOS-like symptoms rats by regulating autophagy. A rat model of was established subcutaneous injection dehydroepiandrosterone (DHEA), then at acupoints (ST29 SP6) carried out for 5 weeks. To...
Acupuncture, a therapy of traditional Chinese medicine, is confirmed to exert the therapeutic action on polycystic ovary syndrome (PCOS). However, detailed mechanisms acupuncture in PCOS remain ambiguous. In this study, we further investigated whether electroacupuncture (EA) alleviated PCOS-like symptoms rats via regulating metabolic regulator, sterol regulatory element binding protein-1 (SREBP1).The rat model was built by hypodermic injection with dehydroepiandrosterone (DHEA). The were...
Mesenchymal stem cells (MSCs) have been optimal targets in the development of cell based therapies, but their limited availability and high death rate after transplantation remains a concern clinical applications. This study describes novel effects platelet rich clot releasate (PRCR) on rat bone marrow-derived MSCs (BM-MSCs), with former driving gene program, which can reduce apoptosis promote regenerative function latter hostile microenvironments through enhancement paracrine/autocrine...
The mesenchymal stem cell (MSC) supernatant is well known as a rich source of autologous cytokines and universally used for tissue regeneration in current clinical medicine. However, the limitation conditioned medium open-wound repair compels need to find more sophisticated way take advantage trophic factors MSCs. We have now fabricated three-dimensional membrane from freeze-dried bone marrow cells-conditioned (FBMSC-CM) using simple protocol. Scanning electron microscopy images showed...
Abstract Centromere protein A (CENP‐A), a centromere‐specific histone H3 variant, is crucial for kinetochore positioning and chromosome segregation. However, its regulatory mechanism in human cells remains incompletely understood. structure‐activity relationship (SAR) study of the cell‐cycle‐arresting indole terpenoid mimic JP18 leads to discovery two more potent analogs, (+)‐6‐Br‐JP18 (+)‐6‐Cl‐JP18. Tubulin identified as potential cellular target these halogenated analogs by using drug...
Adipose-derived stem cells (ASCs) that show multidifferentiation and anti-immune rejection capacities have been widely used in plastic reconstructive surgery. Previous studies indicated mechanical biophysical interactions between their surrounding environment regulate essential processes, such as growth, survival, differentiation, the cytoskeleton system plays an important role mechanotransduction. However, of force determination lineage fate is still unclear. Human ASCs (hASCs) were...
Abstract Background Integrins play a prominent role in osteogenic differentiation by transmitting both mechanical and chemical signals. Integrin expression is closely associated with tensile stress, which has positive effect on differentiation. We investigated the relationship between integrin αVβ3 stress. Methods Human fibroblasts were treated c (RGDyk) lentivirus transduction to inhibit function of αVβ3. Y-15, cytochalasin D verteporfin used phosphorylation FAK, polymerization...
The data of 44 scalp acupuncture schools are collected to analyze their commonalities in theoretical foundations, needling sites, techniques, and indications. integration these characteristics into an optimized, unified protocol has become inevitable trend. paper discusses the potential for a from aspects such as unification, relationships between point areas, lines, needle numbers. It also explores primary issues solutions involved unifying protocols, providing reference standardization...
The structure of chloroplast genomes (cpDNAs) in Fabaceae (Fab.) has undergone significant evolutionary modifications. Within the Papilionoideae (Pap.), emergence Inverted Repeat-Lacking Clade (IRLC) represents a major genomic alteration. However, molecular evolution and phylogenetic relationships within Pap. remain poorly resolved due to limited data incomplete research, highlighting need for systematic investigation. This study presents an in-depth analysis cpDNAs Pap., with aim unraveling...
<title>Abstract</title> <bold>BACKGROUND</bold> Colorectal cancer (CRC) is the third most common and second leading cause of cancer-related deaths globally. CRC its treatment heavily impact patients' physical mental health, often causing limitations, anxiety, depression. Assessing health-related quality life (HRQoL) in patients increasingly recognized as important, but more research needed on influencing factors. <bold>OBJECTIVE</bold> To evaluate colorectal patients, analyze other possible...
This article analyzes the current status of researches on acupuncture-moxibustion for idiopathic facial palsy (Bell's palsy). Acupuncture-moxibustion is widely applied in treatment Bell's and relevant are enriched. But hierarchical discussion effectiveness reported inadequately. Consequently, necessity advantages hardly prominent. Besides, safety not fully explored. The common shortcomings presented professional study statistical designs, quality evidences high. recommendation strength weak...
Pre-trained Vision Mamba~(Vim) models have demonstrated exceptional performance across various computer vision tasks in a computationally efficient manner, attributed to their unique design of selective state space models. To further extend applicability diverse downstream tasks, Vim can be adapted using the fine-tuning technique known as visual prompting. However, existing prompting methods are predominantly tailored for Transformer (ViT)-based that leverage global attention, neglecting...
To compare the efficacy and safety of liraglutide versus sitagliptin as add-on to metformin after 26 weeks treatment in Chinese patients with type 2 diabetes mellitus (T2DM).This 26-week open-label, active comparator trial (NCT02008682) randomized (aged 18-80 years) T2DM inadequately controlled [glycated haemoglobin (HbA1c) 7.0-10.0% (53-86 mmol/mol)] 1 : once-daily subcutaneously administered 1.8 mg (n = 184) or oral 100 184), both metformin. The primary endpoint was change HbA1c from...
Adipose-derived mesenchymal stem cells (ADMSCs) are considered an efficient and important candidate for male infertility treatment because they contain pluripotent cells, which can differentiate into all from three germ layers. However, the generation of germ-like cell (MGLCs) is one key issues, little known about mechanisms underlying MGLCs. Herein, we attempt to improve MGLCs derived during co-culturing rat ADMSCs with SCs under retinoic acid (RA) testosterone (T) treatment. isolated SD...
The thalamus plays a crucial role in sensorimotor, cognitive, and attentional circuit functions. Disruptions thalamic connectivity are believed to underlie the symptoms of multiple sclerosis (MS). Therefore, assessing thalamocortical structural (SC) functional (FC) may provide new insights into mechanism intrinsic plasticity large-scale neural network. We used resting-state FC measurement diffusion tensor imaging probabilistic tractography study integrity system patients with...